• Targeted synthesis of cell penetrating peptides and their conjugation to protein nanoparticles to develop biocompatible drug delivery systems (DDS) aimed for chemotherapeutic use.• Assessment of the drug encapsulation and sustained release of anticancer drugs from the developed protein-peptide nanoparticles.• Comprehensive analysis of partitioning parameters in DDS using light scattering and small angle X-Ray scattering.

• Synthesis of second-generation biocompatible choline based amino acid ionic liquids (ILs) and their biophysical characterization.• Prevention of aggregation/fibrillation of insulin under stress conditions using the ILs with an aim to prepare stable protein formulations for therapeutics.

Biophysical aspects of drug partitioning and biomolecular recognition• Drug encapsulation and release studies from amphiphilic surfactant/ lipid/cholesterol-based drug delivery systems and its interaction with serum proteins.• Assessment of structure-property-energetics correlations of drug partitioning in self-assemblies to obtain guidelines for rational drug design.• Viability and in-vitro performance of the drug incorporated systems in MDAMB-231 breast cancer cells.