Ewa Lis Email & Phone Number

San Diego, CA, US

San Diego, CA, US

• Founded Koliber Biosciences to accelerate biological research through the use of machine learning and data science technologies.
• Developed an Artificial Intelligence platform for peptide / protein discovery, obtained SBIR funding for platform commercialization, established relationships with biotech and academic partners and successfully.
• Established a research lab to enable generation of key proof-of-concept data that brought in over $1M of non-dilutive funding through government grants (SBIR) and start-up competitions (SynBioBeta 2015).
• Delivered key projects on budget and on time including development of models and software for a medical device, signal extraction algorithms for a diagnostic application and lead optimization models for drug discovery.
• Responsible for Machine Learning as a Service projects including leadership of technical team, code prototyping and interactions with customers.

San Diego, CA, US

• Established deep learning pipelines for histopathology image analysis.
• Built automated workflows for model building using state-of-the-art tools and architectures.
• Achieved human level performance on cell classification tasks in women's and men's health disease areas.

San Diego, CA, US

• Technical lead on a high risk proof of concept project geared towards improving product yields via engineering of methanol oxidation into microorganisms.
• Responsible for coordinating research efforts of a multidisciplinary team of 8 scientists and reporting findings to the leadership team.
• In house assay development expert involved in optimizing small scale in vivo assays for several products at Genomatica with focus on predictability at scale.
• Specialist at application of complex design of experiments, multivariate analysis and regression modeling to arrive at data driven solutions to pathway optimization and strain ranking.
• Developed strains for co-utilization of various sugars in complex mixtures including lignocellulosic hydrolysates which resulted in an issued patent.

Waltham, MA, US

• R&D lead of a team of 6 scientists/research associates in the Synthetic Biology division.
• Commercialized a complete toolkit for genetically engineering two algal strains: Chlamydomonas reinhardtii and Synechococcus elongatus.
• Performed key experiments to establish technical feasibility of product components:cryopreserved algal cells and expression vectors.
• Applied Six Sigma principles during product development which resulted in robust system performance and a reliable manufacturing process.
• Presented at several conferences including Biofuels Keystone Symposium in Singapore,Algal Biofuels Symposium at Salk and Synthetic Biology SB5.0 at Stanford.
• Established collaborations with leaders in the field to facilitate state of the art genetic tool development and technology transfer.

• First employee and R&D lead at a biotech start up company developing algal biofuels
• Co-authored a proposal that resulted in series A funding by CMEA Ventures
• Developed synthetic biology tools that enabled discovery of a lipid regulators, secretion of advanced fuel molecules and modulation of lipid profiles in cyanobacteria.
• Initiated strain prospecting efforts that resulted in discovery of cyanobacterial strains with high lipid content which were later established as >60,000 gal monocultures at the scale up facility.
• Technical liaison between founders, staff, scale up facility and executive management.
• Author of 2 grant applications and inventor on an issued patent.

Ph.D., Genetics And Molecular Biology

B.A., Chemistry