Fabien Plisson, Ph.D

Fabien Plisson, Ph.D Email and Phone Number

Drug Discovery, Protein Engineering & AI | Designing innovative protein-based solutions for real-world applications
Fabien Plisson, Ph.D's Location
Sydney, New South Wales, Australia, Australia
Fabien Plisson, Ph.D's Contact Details

Fabien Plisson, Ph.D personal email

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About Fabien Plisson, Ph.D

I am a scientist and entrepreneur with 17 years of experience in drug development, computational techniques, and artificial intelligence. Throughout my career, I have contributed to groundbreaking drug discovery programs through global academic-industry partnerships.Some of my key achievements include:》Advancing the field of anticancer drug design by introducing enzymatic bioconversion combined with multistep organic synthesis to create potent natural product analogs (CNRS & Laboratoires Pierre Fabre, France).》Discovering promising kinase and P-glycoprotein inhibitors through bioassay-guided fractionation and molecular docking, advancing treatments for cancer and neurodegenerative disorders (University of Queensland, Australia, in collaboration with Noscira, Spain).》Designing potent GPCR peptide ligands for type 2 diabetes and acute myeloid leukemia in collaboration with Pfizer (USA) and Protagonist Therapeutics (Australia).》Developing cutting-edge machine learning models for natural product drug discovery and peptide drug design to address infectious diseases in humans, livestock, and crops (Mexico).Through 𝘐𝘯𝘨𝘦𝘯𝘪𝘦 𝘉𝘪𝘰, I am building a platform to integrate AI-driven tools with biomolecular innovation, empowering academic and industrial partners to solve complex research challenges. I am committed to driving innovation through PTNG Scientific offering strategic consulting services via tailored contracts and partnerships. As I expand this initiative, I remain open to R&D leadership roles in academic institutions, biotechnology startups, and pharmaceutical companies, where I can leverage my experience in collaborative, interdisciplinary environments to support the Australian bio-economy and beyond.

Fabien Plisson, Ph.D's Current Company Details

Drug Discovery, Protein Engineering & AI | Designing innovative protein-based solutions for real-world applications
Fabien Plisson, Ph.D Work Experience Details
  • Centro De Investigación Y De Estudios Avanzados Del Ipn
    Associate Professor
    Centro De Investigación Y De Estudios Avanzados Del Ipn Jun 2022 - Jun 2024
    Irapuato, Guanajuato, Mexico
    Associate Professor, Centre for Research and Advanced Studies (CINVESTAV), Unidad Irapuato, Dept. Biotechnology & Biochemistry.
  • Centro De Investigación Y De Estudios Avanzados Del Ipn
    Assistant Professor / Lecturer
    Centro De Investigación Y De Estudios Avanzados Del Ipn Nov 2017 - May 2022
    Irapuato, Guanajuato, Mexico
    Assistant Professor, CONACYT Research Fellow at the Centre for Research and Advanced Studies (CINVESTAV), Advanced Genomics Unit (LANGEBIO)- Research foci at the interfaces between drug discovery, protein engineering and artificial intelligence.- Discovering peptides/proteins using proteo-transcriptomics, structural bioinformatics (e.g. Ab initio modelling) and machine learning algorithms.- Developing generative models for the discovery and design of peptides/proteins with potential applications as anticancer agents, antimicrobials against drug-resistant strains, antivirals or insecticides. - Exploring the production of therapeutic peptides in biological systems such as "Plant Molecular Pharming" to achieve a sustainable and cost-effective bio-manufacturing, in addition to chemical synthesis.More information at http://www.langebio.cinvestav.mx/
  • Self-Employed
    Data Science Consultant
    Self-Employed Jan 2017 - Jun 2024
    León Area, Mexico
    Provided (pro bono) consulting and mentoring services in data science and health to local start-upHealth Data https://healthdataprogram.com/ Developed a 40 h materials and practices in R/R Studio for Integratek Mexico http://www.integratekmexico.com/including statistics, unsupervised and supervised machine learning algorithms
  • Insight Data Science
    Health Data Science Fellow
    Insight Data Science Sep 2016 - Feb 2017
    Boston, Ma, Us
    Developed insightful analytics & creating data science solutions to solve problems in the health sector with pharmaceutical / biotech and tech partners (insighthealthdata.com).Reac2vac.online - Your Doctor's Guide to Vaccine Adverse Events- Applied natural language processing, regular expression, unsupervised and supervised machine learning techniques to 450,000 reports from the VAERS database, the US surveillance program tracking relationships (if any) between adverse events (mild-to-severe) and vaccines.- Analyzed, processed the data using R (dplyr, reshape2) and Python (pandas, scikitlearn).Created an online web application using Flask / Bootstrap applying HTML / CSS / JSON programming. The web application is running via Amazon Web Services (EBS-optimised EC2 instance).- The project has been created from scratch to web delivery under 3 weeks.
  • The University Of Queensland
    Industry Fellow
    The University Of Queensland Oct 2015 - Feb 2016
    Brisbane, Australia
    Measured the impact of sprayed herbicides over soil microbiomes in banana and sugar cane plantations from North Queensland. Metabolomic studies conducted between the School of Agriculture and Food Sciences, the Department of Agriculture and Fisheries (Queensland) and the Queensland Alliance forEnvironmental Health Sciences (ex-EnTox).
  • Protagonist Therapeutics / Pharmacy Australia Centre Of Excellence
    Research Officer
    Protagonist Therapeutics / Pharmacy Australia Centre Of Excellence Jun 2015 - Oct 2015
    Brisbane, Australia
    Synthesized peptide therapeutics inhibiting protein-protein interactions and molecular probes to understand their cellular internalisation. Group leaders: Prof. Tom Gonda (Pharmacy Australia Centre of Excellence) & Assoc. Prof. Mark Smythe (Protagonist Pty Ltd)
  • Pfizer / Institute For Molecular Bioscience
    Postdoctoral Researcher
    Pfizer / Institute For Molecular Bioscience Aug 2012 - Feb 2015
    Brisbane, Australia
    Designed and developed peptide therapeutics for the treatment of type 2 diabetes at the Institute for Molecular Bioscience in collaboration with pharmaceutical company Pfizer (Groton & Boston, USA). Applied solid-phase peptide synthesis, NMR and CD spectroscopy, Computer-Aided Drug Design with conformer generation and exploratory data analysis (R, Schrodinger)Group Leader: Prof. David Fairlie (IMB, UQ)Collaborators: Prof. David Craik (IMB, UQ) and David Price, David Griffith, David Edmonds, Spiros Liras (Pfizer)
  • Uq Institute For Molecular Bioscience
    Doctoral Researcher
    Uq Institute For Molecular Bioscience Sep 2008 - Jun 2012
    Brisbane, Australia
    Bioassay-guided discovery of new kinase inhibitors (hits/leads) from marine sources for treating neurodegenerative disorders between Prof. Rob Capon Lab and Noscira (Madrid, Spain): - Isolated, purified, elucidated small molecule natural products (NMR, HPLC, UV, CD)- Applied molecular docking and virtual screening approaches to in-house compounds library (NP repurposing)- Synthesized and established structural-activity relationship studies using natural product-inspired fragments. - Developed seminal machine-learning models to predict blood-brain barrier permeability for natural products.Discovery of new antimalarial agents from natural and synthetic in-house libraries (>2000) in collaboration with the Queensland Institute for Medical Research (QIMR), Brisbane.Team Leader: Dr Andrew PiggottSupervised PhD student Olusegun S. Ajala in 2010
  • Pierre Fabre / French National Centre For Scientific Research
    Research Intern + Cnrs Research Engineer
    Pierre Fabre / French National Centre For Scientific Research Mar 2007 - May 2008
    Toulouse Area, France
    Lead optimization programs in the Natural Products section of the 'Institute Sciences and Technologies for Drug of Toulouse, Pierre Fabre LaboratoriesSupervisors: Dr Fadila Derguini and Dr Georges Massiot (CNRS)Co-inventor of one patent and co-author in 2 publications.Co-supervision of two postgraduate students, Julien Grisel and Florie Lavigne, France (2008)
  • University Of Aberdeen
    Research Internship
    University Of Aberdeen Jun 2006 - Sep 2006
    Abderdeen, Scotland
    Discovery of secondary metabolites from marine organisms and fijian plant Qiqila - Extraction, isolation using normal and reverse separative columns (silica gel and HPLC) from complex natural extracts. Structural elucidation using 1D/2D NMR Analysis (TOPSPIN) and Mass Spectrometry measurements.Supervisor: Prof. Marcel JasparsCo-supervisor: Dr Jioji Tabudravu
  • Various Companies
    Summer Staff
    Various Companies Jul 1999 - Sep 2005
    Provence-Alpes-Côte D'Azur, France
    1999 Icecream maker - La Bonne Auberge2000-2001 Retail stock clerk - Carrefour2002 Gate Keeper - Camp du Domaine2003-2005 Bar waiter - Camp du DomaineOther skills: Retail, Sales, Hospitality, Languages (French***, English**, Spanish*)
  • University Of Hull
    Research Internship
    University Of Hull Apr 2005 - Jun 2005
    Hull, England
    Synthesis of highly conjugated macromolecules exhibiting liquid-crystal properties. Suzuki and Sonogashira reactions were routinely employed. Structural elucidation by spectroscopic analysis.Supervisor: Prof. Georg Mehl

Fabien Plisson, Ph.D Skills

Drug Discovery Hplc Nmr Chemistry Mass Spectrometry Organic Synthesis Organic Chemistry Chromatography Laboratory Medicinal Chemistry Peptides Drug Design Project Management R&d Data Analysis Analytical Chemistry Qsar Spectroscopy Molecular Modeling Team Coordination Data Mining R Python Machine Learning Pharmaceutical Industry Intellectual Property Purification Natural Products Lc Ms Research Biotechnology Science Statistics

Frequently Asked Questions about Fabien Plisson, Ph.D

What is Fabien Plisson, Ph.D's role at the current company?

Fabien Plisson, Ph.D's current role is Drug Discovery, Protein Engineering & AI | Designing innovative protein-based solutions for real-world applications.

What is Fabien Plisson, Ph.D's email address?

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What is Fabien Plisson, Ph.D's direct phone number?

Fabien Plisson, Ph.D's direct phone number is +185723*****

What schools did Fabien Plisson, Ph.D attend?

Fabien Plisson, Ph.D attended The University Of Queensland, Ecole Nationale Supérieure De Chimie De Montpellier, Ecole Nationale Supérieure De Chimie De Montpellier, Ecole Nationale Supérieure De Chimie De Montpellier, Université De La Méditerranée (Aix-Marseille Ii), Université Du Sud Toulon Var.

What are some of Fabien Plisson, Ph.D's interests?

Fabien Plisson, Ph.D has interest in Pharma And Biotechnologies, Underwater Sports And Sustainability, Health Data Science + Data Visualisation, Consulting, Education, New Technologies, Decision Making, Health.

What skills is Fabien Plisson, Ph.D known for?

Fabien Plisson, Ph.D has skills like Drug Discovery, Hplc, Nmr, Chemistry, Mass Spectrometry, Organic Synthesis, Organic Chemistry, Chromatography, Laboratory, Medicinal Chemistry, Peptides, Drug Design.

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