Fe Wright, Cvt, Dvm Email & Phone Number

Philadelphia, Pennsylvania, United States

• Assists in the management of R&D activities conducted by the PCM rodent program. Provides oversight and quality control of PCM generated study data and documentation. Ensures/provides guidance in scheduling of procedural training activities, timely completion and documentation of training of rodent research staff and study teams across PCM. Conducts regular and annual review of individual training records for teams within the program. Has oversight for documentation of continued refinement of… Show more • Assists in the management of R&D activities conducted by the PCM rodent program. Provides oversight and quality control of PCM generated study data and documentation. Ensures/provides guidance in scheduling of procedural training activities, timely completion and documentation of training of rodent research staff and study teams across PCM. Conducts regular and annual review of individual training records for teams within the program. Has oversight for documentation of continued refinement of specialized techniques to keep abreast with state-of-the-art scientific innovation in support of gene therapy studies. Spearheaded by specialized core groups of study teams within the program, effective completion of supported gene therapy studies underpin the success of accomplishing overarching objectives of the program.• Subject matter expert in rodent echocardiography and electrocardiography. Delivers workshop teaching presentations to scientists within the program. Established rodent echocardiography capability within the program. Spearheaded acquisition of Vevo 3100 imaging platform and VevoLab Analysis software, and successful collaboration in network connectivity of equipment for secure export, management and archival of data. Trains staff in image acquisition and analysis.• Participates in leadership meetings. Collaborates with cross functional groups to address operational, research related, and veterinary care activities as needed. Interacts with Study Directors and AMC Management on study design, protocol development, initiation, methods development, technical execution of echocardiography rodent studies. Provides technical expertise, model development, method validation for pre IND, IND and BLA studies as required.• Assists the veterinary staff in the evaluation and treatment of clinical cases of rodent adverse phenotypes with a good grasp phenotypic endpoints and respective translational components of their disorders. Show less

Philadelphia, Pennsylvania, United States

• Led a team of highly skilled in vivo research specialists and research technicians whose technical expertise support and drive the momentum of pre-clinical gene therapy studies for PCM at the Perelman School of Medicine, Translational Research Laboratories of the University of Pennsylvania. This dynamic rodent research program is instrumental for the in life phase of gene therapeutics prior to human application. Serving the largest program of comparative medicine in gene therapy for rare… Show more • Led a team of highly skilled in vivo research specialists and research technicians whose technical expertise support and drive the momentum of pre-clinical gene therapy studies for PCM at the Perelman School of Medicine, Translational Research Laboratories of the University of Pennsylvania. This dynamic rodent research program is instrumental for the in life phase of gene therapeutics prior to human application. Serving the largest program of comparative medicine in gene therapy for rare orphan diseases in the county, and with internationally based collaborators, study support include: basic research, development of platform technologies, development of vector manufacturing methods, pre-clinical research for liver diseases, neurodegenerative disorders, and storage diseases to mention a few. This program supports more than six study directors and their teams with technical and scientific research procedures for gene therapy studies investigating a wide spectrum of rare diseases in mouse models with adverse phenotypes.• Created a highly organized Rodent Research Program file within 5 months of employment. This file includes clinical treatment excel worksheets, historic treatment log sheets, sick animal reporting flow charts, files of clinical observations of active and resolved clinical cases, and documentation of archival of completed studies. It also holds 24/7 work schedule of veterinary and rodent research support team, documentation of completed training with 100% completion of rodent research team's 2019 training goals. To date, this file remains as exceptional resource of information providing transparency of records and documentation across PCM.• Participated in corrective/preventative action plan (CAPA) processes to ensure timely implementation of CAPAs.• Ensured compliance with regulations governing the humane and ethical treatment and use of laboratory animals used in gene therapy research, regulatory compliance and Good Laboratory Practices. Show less

Upper Merion, King Of Prussia, Pa

• Resident echo imaging expert at GSK. • Collaborated with Thomas Jefferson University for a capability build to perform photoacoustic imaging on breast and ovarian cancer tumor models using antibodies conjugated with NIR dyes. Responsible for submission of third-party agreements and dossier component applications to meet both parties’ standards for content, quality, and regulatory requirements.• Contributed to imaging excellence by providing training and standardization of… Show more • Resident echo imaging expert at GSK. • Collaborated with Thomas Jefferson University for a capability build to perform photoacoustic imaging on breast and ovarian cancer tumor models using antibodies conjugated with NIR dyes. Responsible for submission of third-party agreements and dossier component applications to meet both parties’ standards for content, quality, and regulatory requirements.• Contributed to imaging excellence by providing training and standardization of protocols and documents. Validated scientists in image acquisition and analysis. Exercised scientific rigor in peer review of images, numerical data and statistical analysis. Provided guidance in conduct of studies with strict adherence to standardized parameters and algorithms in the protocol to minimize variability with an end goal of delivering quality data and robust results. With continuous improvement and innovation, consistently upheld company standards of scientific integrity to ensure overall safety of patients. • Proactive in identification, mitigation and committed in collaboratively finding resolution to critical issues encountered during studies, observed effective management of time across multiple tasks within projects whilst working on simultaneous projects in tandem and ensured delivery of results to agreed timelines and meet deadlines.• Trained on GE Vivid 9 ultrasound system, operated GE Vivid 7, Vevo 2100 US systems and Vevo 2100 photoacoustic LAZR imaging platforms. Managed vendors and assured that systems met required preventative maintenance, validation, and that generated data followed GSK’s data integrity requirements and conformed to regulatory expectations. Managed process improvement initiatives in data capture, data reconciliation and archival. Contributed to system specific imaging SOP’s and data transfer specifications. Provided suitable recommendations/mutual solutions that show measurable improvement and added value to internal/external customers. Show less

• Race and Ethnicity Council AERG representative with solid understanding of the I&D strategy, collaboratively provided input applicable to the strategy elements required to meet BU goals. Understood the dynamic R&D environment and its emerging programs. Adapted I&D strategies and supported implementation of programs relevant to needs of respective BUs.• Recruited support and endorsements from top level AERG executive sponsors and pull through of I&D programs via close collaboration… Show more • Race and Ethnicity Council AERG representative with solid understanding of the I&D strategy, collaboratively provided input applicable to the strategy elements required to meet BU goals. Understood the dynamic R&D environment and its emerging programs. Adapted I&D strategies and supported implementation of programs relevant to needs of respective BUs.• Recruited support and endorsements from top level AERG executive sponsors and pull through of I&D programs via close collaboration with the I&D HR ERG BL to coordinate implementation of programs. Engaged with US & Asian countries HR BLs to understand the landscape of I&D space in Asia, sought to identify programs that could be of value to get incorporated to U.S. best practices. • Collaborated with multidisciplinary colleagues in a broadly matrixed environment. Influenced engagement of AERG chapter leads to diverse reverse mentor BLs and global top executive leaders regarding inherent diversity of thoughts and behaviors of Asian culture that impact productivity and engagement in the workplace. Recommended best practices to be adopted in the workplace.• Developed enterprise wide outreach partners as speaker and subject matter expert highlighting the “Role of Bioimaging in the Pharmaceutical Industry” at The SASE National Conference and STEM Career Fair, 2017. In collaboration with the HR I&D recruitment team, these partnerships achieved business aligned recruitment objective with 3,000 attendees from the academe, big pharma and engineering industries.• Ensured that beneficial relationships existed between the US AERG Enterprise Chapters, internal employee networks and outreach organizations. Monitored and tracked progress of internal activities and community outreach efforts against business aligned objectives at a national and local level. Identified gaps, escalated and coordinated enterprise resolutions by leveraging engagement of other ERGs, diversity organizations and executive sponsors as necessary. Show less

King Of Prussia, Pa

• Resident echo imaging expert at GSK. Managed and conducted investigative, non-GLP component of GLP safety pharmacology toxicology in-vivo echo imaging studies in canine and non-human primates, phenotype characterization, efficacy and dose response studies in rodent animal models of heart failure in support of assets' progression to candidate selection and 1st time in human studies.• Responsible for authoring SOPs to standardize echo imaging protocol image acquisition and analysis… Show more • Resident echo imaging expert at GSK. Managed and conducted investigative, non-GLP component of GLP safety pharmacology toxicology in-vivo echo imaging studies in canine and non-human primates, phenotype characterization, efficacy and dose response studies in rodent animal models of heart failure in support of assets' progression to candidate selection and 1st time in human studies.• Responsible for authoring SOPs to standardize echo imaging protocol image acquisition and analysis with a translational approach to the evaluation of drug related cardiovascular risk within GSK and in partnership with consortium of experts from the academe, FDA and big pharmaceutical industries.• Authored and peer reviewed materials and methods of articles and case reports. Developed, implemented customized training programs and conducted peer reviews to validate, certify and/ or support development needs of student externs, post-doctoral fellows and junior scientists.• Developed enterprise wide outreach partners as speaker and subject matter expert at numerous, highly visible national conferences and workshops to certify international audience of research veterinarians and veterinary technicians in NHP echocardiography, abdominal ultrasound and Basic ECG rhythm analysis and interpretation. • Authored study protocols, expert contributor’s reports, statistical reports, and numerous presentations to showcase data summary and interpretation. Defended validity of results and analyses of data as subject matter expert. Communicated to stakeholders appropriate recommendations for future studies. Followed data integrity policies for archival of study reports. Show less

Gladwyne, Pa

• Quantitatively analyzed and measured electrocardiogram intervals for major national and international pharmaceutical companies conducting toxicological and pharmacological studies.