Fabien Hammerer, Phd Email & Phone Number

- Provided guidance to $300k R&D project for the degradation of rubber materials.- Designed enzymatic cascades to trigger polymer breakdown.- Advised 3 employees in planning and executing experiments to achieve goals.- Initiated collaboration with partner to produce non-commercial enzyme.- Provided expert insights in regular progress meetings with funding.

Montreal, Quebec, CA

Taught CEGEP level chemistry courses. Identified ways to engage students in class and remote environment. Taking student feedback in consideration to improve teaching performance.

Montreal, Qc, CA

• Designed and patented techniques for solvent-free enzymatic digestion of several biopolymers: cellulose, hemicellulose, lignocellulose and chitin. Trained several students and postdocs in using these methods to develop.
• Achieved fast digestion of untreated lignocellulosic biomass (up to 85% in 13h).
• Initiated multiple projects including the development of the first in situ methods to monitor solvent-free enzymatic reactions using solid-state NMR, PXRD, or fluorescence spectroscopies.
• Improved reproducibility in the lab: wrote SOPs, established good laboratory practices, created a wiki to facilitate experience transfer.

Montreal, Qc, CA

• Led the development of a novel anti-bacterial strategy targeting resistance pathways to host immune system response. Demonstrated its potential on Salmonella.
• Trained multiple students and interns in using the corresponding chemical techniques and microbiological assays
• Identified hit compound: synthesized and characterized a library of pantothenate analogs susceptible to be transformed by CoA-generating enzymes, developed and perfected synthetic routes, screened candidates.
• Designed and validated multiple assays: a whole-cell assays (MIC, checkerboard) to evaluate pro-drug efficacy; LC-MS methods to monitor pro-drug transformation (in vitro, in cellulo) and stability.
• Identified biocatalysis products using standards I synthesized. Purified biocatalytic reaction mixtures using homemade molecularly imprinted polymers.
• Established a leadership role in the operations of the group and mentored graduate students in order to complete projects; led inventory update and reordering.

Montreal, Qc, CA

Under the supervision of K. AuclairStudied the re-sensitization of a Salmonella subspecies to itaconate, a natural antibiotic secreted by macrophages during phagolysis. Following a prodrug approach, the molecules developed are activated in bacteria through the natural Co-enzyme A biosynthesis pathway to inhibit the enzymes responsible for itaconate.

Orsay, Ile-de-France, FR

• Under the supervision of Prof. J.-P. Mahy
• Synthesized porphyrin-containing artificial enzymes for redox photocatalysis with water or oxygen as oxidant.
• Created porphyrin-containing artificial enzymes for photoredox biocatalysis.
• Expressed and purified wild-type xylanase A and one mutant.
• Identified and quantified photocatalysis products (GC).
• Screened libraries of proteins and metal complexes to identify new affinity complexes.

Paris, Île-de-France, FR

• Prepared students from "Classe Préparatoires aux Grandes Ecoles" (CPGE, intensive preparation to competitve exams to enter prestigious engineer schools)
• Tutoring: weekly preparation of personal courses and exercises to match the student's specific needs (organic and general chemistry, spectroscopy).
• Group tutorials in general chemistry.

Paris, FR

• Synthesized and evaluated new two-photon sensitizers for the photodynamic treatment of retinoblastoma. Identified new promising scaffold targeting mitochondrial DNA.
• Multi-step synthesis of π-conjugated porphyrins and triphenylamines (up to 11 steps).
• Spectroscopic characterizations (UV/vis, fluorescence, singlet oxygen).
• Fluorescence microscopy of fixed cells.

Bagneux, FR

Doctor Of Philosophy (Ph.D.), Chemistry

Master'S Degree, Chemistry

Master, Chimie Bioorganique Et Bioinorganique

Magistère, Physicochimie Moléculaire