Florian Muller Email & Phone Number
@cancerpreventiontraining.org
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Who is Florian Muller? Overview
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Florian Muller is listed as Chief Scientific Officer at Lindonlight Collective, based in Houston, Texas, United States. AeroLeads shows a work email signal at cancerpreventiontraining.org and a matched LinkedIn profile for Florian Muller.
Florian Muller previously worked as Head of Chemistry at Lindonlight Collective and Sr. Director of Cancer Biology at Sporos Bioventures. Florian Muller holds Post-Doctoral Training, Molecular Oncology from Harvard Medical School.
Email format at Lindonlight Collective
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About Florian Muller
I am driven by a passionate curiosity for the natural world and I see my life as an enduring quest for knowledge. My current work centers on bringing together cancer genomics and metabolism, to develop novel molecular targeted therapeutics. We have pioneered a novel approach to precision oncology, collateral lethality, which utilizes passenger deletions of housekeeping genes as points of metabolic vulnerabilities. Our most advanced iteration of this strategy consists of targeting tumors with ENO1 homozygous deletions (occur in GBM, HCC, CHOL) by inhibitors of the redundant paralogue, ENO2. We generate a small molecule ENO2 inhibitor, HEX with pro-drugs of HEX showing potent pre-clinical activity and good tolerance in NHP. At the same time, I see passenger deleted genes as natural experiments that can inform on key aspects of tumor biology, including immune system/tumor interactions.
Listed skills include Biochemistry, Molecular Biology, Cancer, Cell Biology, and 33 others.
Florian Muller's current company
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Florian Muller work experience
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Head Of Chemistry
Venture Philanthropy to improve outcomes in pediatric lower grade glioma
Sr. Director Of Cancer Biology
Assistant Professor
Tenure Track position in the Department of Cancer Systems Imaging and Department of Neurooncology
Assistant Professor
Postdoctoral Fellow
My post-doctoral training was in the lab of Ronald DePinho on Mayer 4 at Dana Farber Cancer Institute. While I initially joined the lab to work on the biology of aging, this incredible environment in cancer hospital setting stimulated my interest in cancer metabolism and therapeutics. During the first few years in the DePinho lab, I studied the role of Foxo transcription factors in aging and neurodegeneration in close collaboration with JiHye Paik. Our key finding was that neuron-specific knockout of Foxo1 results in a dramatic acceleration of aging-related axonal tract degeneration. Other collaborations with Mariela Jaskeliof and Ergun Sahin, concerned the role of telomerase in aging.
Graduate Student Researcher
My graduate research concerned the mechanism of reaction oxygen species (Superoxide) production by the mitochondrial electron transport chain and its pathophysiological implications for Aging and Neurodegeneration. Highlights from my work during this time, include the finding that Superoxide produced at the Qo site of mitochondrial Complex III can reach both sides of the inner mitochondrial membrane and hence exert oxidative damage in both the mitochondrial matrix and the cytosol. The physiological importance of cytosolic superoxide is highlighted by the dramatic acceleration of aging-related sarcopenia that we observe in Sod1-/- mice.
Research Assitant
Florian Muller education
Post-Doctoral Training, Molecular Oncology
Ph.D., Cell And Structural Biology
B.S., Biochemistry, Biophysics And Molecular Biology
Frequently asked questions about Florian Muller
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What company does Florian Muller work for?
Florian Muller works for Lindonlight Collective.
What is Florian Muller's role at Lindonlight Collective?
Florian Muller is listed as Chief Scientific Officer at Lindonlight Collective.
What is Florian Muller's email address?
AeroLeads has found 1 work email signal at @cancerpreventiontraining.org for Florian Muller at Lindonlight Collective.
Where is Florian Muller based?
Florian Muller is based in Houston, Texas, United States while working with Lindonlight Collective.
What companies has Florian Muller worked for?
Florian Muller has worked for Lindonlight Collective, Sporos Bioventures, University Of Texas M.D. Anderson Cancer Center, Dana-Farber Cancer Institute, and Graduate School Of Biomedical Sciences At The University Of Texas Health Science Center San Antonio.
How can I contact Florian Muller?
You can use AeroLeads to view verified contact signals for Florian Muller at Lindonlight Collective, including work email, phone, and LinkedIn data when available.
What schools did Florian Muller attend?
Florian Muller holds Post-Doctoral Training, Molecular Oncology from Harvard Medical School.
What skills is Florian Muller known for?
Florian Muller is listed with skills including Biochemistry, Molecular Biology, Cancer, Cell Biology, Cell Culture, Science, Genetics, and Research.
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