• National and international oncology leader, educator, scientist, speaker, consultant. • Academic Career/Professorships): Asst Professor of Neurosurgery, School of Medicine, University of Washington, Seattle; Olive Stringer Distinguished Professor, University of Texas MD Anderson Cancer Center; Margaret Harris & David Silverman Distinguished Professor of Neuro-Oncology, Duke University School of Medicine; Distinguished Professor Emeritus of Neurosurgery, Duke University School of Medicine• Administrative Professional Experience: Chairman, Department of Pediatric Cancer and Director of Neurosurgery Research at MD Anderson Cancer Center, Houston, TX; Associate Director of Duke University Cancer Center; Co-Director of Duke University Program of Excellence in Brain Tumors. • Medical/Scientific Advisory Boards and committees of several cancer organizations, including, American Brain Tumor Society, the American Association for Cancer Research, and the Pediatric Brain Tumor Foundation of the United States; Board of Scientific Advisors of the National Cancer Institute, NIH (USA); External Advisory Board, University of Iowa Holden Comprehensive Cancer Center; External Advisory Board, UCLA Brain Tumor Program; Editorial boards of several leading cancer and medical journals; Member of grant review committees of the NCI, NIH (USA) and various national/international institutions/organizations; Consultant to biomedical/pharma industry.• Professional Expertise/Research: Translational oncology; Primary malignant tumors (gliomas) and metastatic cancers of the central nervous system; cancer treatment resistance; targeted “smart” anticancer drugs; personalized cancer therapy. Major discoveries include: Cloning/characterization of genes that mediate cancer risk and drive resistance to therapy in cancer patients (GSTP1, shelterin, gli1, DNA damage/repair); Capillary human tumor cloning - development and clinical application. • Principal Investigator on multiple research grants and awards from NCI/NIH, private foundations and industry (1985-present).• Authored more than 160 scientific papers, meeting abstracts and book chapters; edited two books, one on brain tumors.• US Presidential appointment to the National Cancer Advisory Board (NCAB) of the United States; Member, NCAB Clinical Investigations Sub-committee and Chair, NCAB Global Health Sub-Committee.