Frank Kayser

Frank Kayser Email and Phone Number

VP of Drug Discovery @ Nitrase Therapeutics
Frank Kayser's Location
San Rafael, California, United States, United States
Frank Kayser's Contact Details
About Frank Kayser

Drug discovery expert with 20+ years of senior-level experience in pharmaceutical and biotech industry. Led multidisciplinary teams to progress compounds for separate therapeutic areas (immunology, metabolic disorders, oncology) from early chemical leads into optimized clinical development candidates (FIH). Expertise in organic/medicinal chemistry, structure-based drug design, enzymatic targets, nuclear receptors, GPCR’s, and protein-protein interaction targets, in vitro and in vivo pharmacology, hit-to-lead and lead optimization efforts.Strong experience leading joint efforts between in-house chemists and external partners / CRO’s.Inventor on more than 40 US-issued patents and many more pending US and PCT applicationsSpecialties: organic chemistry, medicinal chemistry, structure-based drug design, hit-to-lead, lead optimization, pharmacology, enzymatic targets, GPCR's, nuclear receptors, protein-protein interaction targets.

Frank Kayser's Current Company Details
Nitrase Therapeutics

Nitrase Therapeutics

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VP of Drug Discovery
Frank Kayser Work Experience Details
  • Nitrase Therapeutics
    Vp Drug Discovery
    Nitrase Therapeutics Jun 2022 - Present
    Brisbane, California, Us
  • Bioardis
    Senior Vp Drug Discovery
    Bioardis Sep 2018 - Jun 2022
  • Bioduro
    Senior Vp Chemistry, Integrated Programs
    Bioduro May 2016 - Sep 2018
    Irvine, California, Us
  • Kayser Consulting, Llc.
    Principal
    Kayser Consulting, Llc. Jun 2014 - Apr 2016
    Kayser Consulting provides Life-Science companies with expertise in small molecule drug discovery.• Optimizing drug discovery strategy for projects, including improving IP positioning• Evaluation of portfolios, programs, leads, drug candidates.• Help in launch of companies, implementing research and drug discovery pipeline.• Expertise in virtual business model; manage resources at CRO’s.
  • Nurix, Inc.
    Head Of Chemistry
    Nurix, Inc. Mar 2012 - Jun 2014
    Head of chemistry, engaged in launching company chemistry efforts, evaluation of therapeutic targets, as well as hit identification and hit-to-lead optimization strategies.
  • Amgen
    Scientific Director
    Amgen Aug 2004 - Dec 2011
    Thousand Oaks, Ca, Us
    Successfully advanced multiple programs in various therapeutic areas, such as metabolic disorders, inflammation, neuroscience and oncology into preclinical and clinical development.Successfully led efforts on a cardiovascular program advancing from early chemical lead into optimized pre-clinical drug candidate.Mentored and set objectives for several medicinal chemistry teams. Led hit-to-lead efforts across multiple Amgen sites.
  • Tularik Inc.
    Sr. Principal Scientist
    Tularik Inc. 2000 - 2004
    Us
    Led chemistry efforts on multiple programs from multiple therapeutic areas.Identified lead, initiated chemistry and assumed project leadership for DGAT-1 project, which later advanced into clinical development.Led chemistry efforts at Tularik Pharmaceutical Company, a collaborative effort between Tularik Inc. and Japan Tobacco for multiple targets in the area of metabolic diseases, delivering high quality development candidates Served as a liaison between chemists at Tularik Inc. and Japan Tobacco.Responsible for hit-to-lead efforts and multiple early stage projects.
  • Merck Research Laboratories
    Research Fellow
    Merck Research Laboratories Nov 1996 - Apr 2000
    Designed and synthesized a small molecule inhibitor of the chemokine receptor CCR3 for the treatment of asthma, which did advance to become a Safety Assessment Candidate (SAC).
  • Merck Research Laboratories
    Sr. Research Chemist
    Merck Research Laboratories Jun 1994 - Nov 1996
    Design and synthesis of small molecule therapeutics in the field of immunology.Designed triterpene derivatives useful as KV1.3 potassium channel inhibitors for the treatment of autoimmune disorders.

Frank Kayser Skills

Drug Discovery Medicinal Chemistry Drug Design Organic Chemistry Pharmaceutical Industry Chemistry Gpcrs Lead Change Organic Synthesis Oncology Immunology Drug Development Cancer Small Molecules Biotechnology Neuroscience Pharmaceutical Research Metabolism Heterocyclic Chemistry Hit To Lead Life Sciences Cross Functional Team Leadership Lead Optimization Synthetic Chemistry Metabolic Diseases Dmpk Clinical Development Pharmacology

Frank Kayser Education Details

  • Uc Santa Barbara
    Uc Santa Barbara
    Chemistry
  • The Philipp University Of Marburg
    The Philipp University Of Marburg
    Chemistry

Frequently Asked Questions about Frank Kayser

What company does Frank Kayser work for?

Frank Kayser works for Nitrase Therapeutics

What is Frank Kayser's role at the current company?

Frank Kayser's current role is VP of Drug Discovery.

What is Frank Kayser's email address?

Frank Kayser's email address is fk****@****ail.com

What schools did Frank Kayser attend?

Frank Kayser attended Uc Santa Barbara, The Philipp University Of Marburg.

What are some of Frank Kayser's interests?

Frank Kayser has interest in Cooking, Exercise, Electronics, Outdoors, Home Improvement, Reading, Music, Travel, Movies, Home Decoration.

What skills is Frank Kayser known for?

Frank Kayser has skills like Drug Discovery, Medicinal Chemistry, Drug Design, Organic Chemistry, Pharmaceutical Industry, Chemistry, Gpcrs, Lead Change, Organic Synthesis, Oncology, Immunology, Drug Development.

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