Team leader data and image analysis

• Development of a novel transcript specific mRNP purification method, which allows the unbiased identification of associated proteins by quantitative proteomics.

• Development of a single-molecule method for imaging the first round of translation in Drosophila, which allowed for the first time to visualize the event of translation in vivo. First author publication and co-author of a book chapter.• Development of a novel transcript specific mRNP purification method, which allows the unbiased identification of associated proteins by quantitative proteomics.

• Development of an quantitative high-throughput image-based screen for chemical compound inhibitors to identify kinases involved in the formation and dissolution of stress granules• Molecular characterization of hits by quantitative phospho-proteomics and kinase substrate profiling, which identified a new regulatory mechanism linking cytoplasmic compartmentalization via liquid phase transitions to cellular signaling.

Diplomarbeit:The role of DYRK3 in virus infection of human cells