Research Lab "GMP & T cell therapy" - Prof. Dr. Stefan B. EichmüllerTopic: Functional validation of multiple myeloma-specific T cell receptorsApplied Methods: Illumina sequencing analysis, golden gate assembly, in vitro transcription, mRNA transfection via electroporation, rapid expansion of patient T cells, co-culture using patient samples, PBMC and BMDC isolation, 5 colour flow cytometry

Research Lab "Tumor-Stroma Communication" - Dr. Juan Rodríguez VitaTopic: The role of macrophages in cancer-associated immunosuppressionApplied Methods: Cell culture of adherent cells, extraction and differentiation of BMDMs, transfection, RNA-Isolation, cDNA synthesis, qPCR, Immunofluorescence, Western Blot

Main Tasks:- Support with pharmaceutical and medical-scientific inquiries from the sales force, physicians and pharmacists on all oncological and haematological products - especially with regard to pharmacological, pharmacokinetic, toxicological effects and side effects as well as the current data situation on the products- Literature research- Supporting the Medical Advisor, for example in the preparation of study results and scientific content- Support with the implementation of technical and package leaflets- Research and preparation of scientific content for digital platforms, e.g. from scientific publications- Support in the organization/supervision of study projects after approval of the preparation

Research Lab Gynecologic Oncology (AG Reinartz) - Dr. Silke Reinartz Topic of bachelor’s thesis: Influence of macrophage-derived TSG6 and Serglycin on the mesothelial integrity and subsequent metastasis in ovarian carcinomaApplied Methods: RNA-Isolation, cDNA synthesis, qPCR, cultivation of adherent cell lines, Co-Culture with primary cells, purification of PBMCs, differentiation of monocytes out of blood, cell adhesion assay, transwell invasion assay, Annexin V Assay, Immunofluorescence, Western Blot