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Fu Chen is listed as Director of Formulation Development based in South San Francisco, California, United States. AeroLeads shows a work email signal at drugdeliveryexperts.com and a matched LinkedIn profile for Fu Chen.
Fu Chen previously worked as Director of Formulation Development at Genprex, Inc. and Consultant at California. Fu Chen holds Course Certificates And Certified Badge, Project Management, Risk Management from Gale/Library, Edx/Ibdx/Pmi.
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1. More than 15 years of successful experience and accomplishments in food, chemical, biotech and pharmaceutical industries (drug discovery and development); 2. Development of lipid nanoparticle (LNP) formulations for siRNA, microRNA, mRNA and CRISPR-Casx delivery for cancer or other treatments. 3. Pre-formulation study and formulation development for polypeptide/protein drug delivery with controlled/sustained/extended release through iv/sc/oral or ocular routes.4. Pre-formulation study and formulation development for plasmid DNA (gene) delivery.5. Manage CRO and CDMO6. Developed and qualified analytical methods for the characterization of small molecule, oligonucleotide/siRNA, polymers/polymer-conjugates, lipid nanoparticle (LNP)/liposome formulations, and polymer-siRNA conjugates.7. Extensive experience in instrument hardware, and strong analytical software skills. 8 Syntheses of Lipid, lipid-conjugates, polymer-polymer conjugates, combinatory libraries. 9. Creative thinking, excellent problem solving across multidiscipline.10. Complex project management and risk management with cross-functional team in biotech and pharmaceutical industries.11. Proficient in data organization, analysis and interpretation.
Listed skills include Analytical Method Development And Validation For Characterizations, Efficient Data Management And Statistical Analysis, Instrument Trouble Shooting And Maintenance, Polymer Characterization, and 5 others.
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Austin, Texas, Us
Non-viral lipid nanoparticle (LNP) delivery of Nucleic acids (DNA/pDNA) for cancer therapy.Analytical method development, qualification and validation for characterization. Stability study design, implementation, data analysis and interpretation.Write and approve study protocols/SOPs. Manage CRO/CDMO.
siRNA drug discovery and development; siRNA design, modification, conjugation, lipid nanoparticle (LNP) formulation and delivery.mRNA drug development, formulation and delivery.peptide drug development, formulation for sustained/extended release.Polymer and polymer drug development.Analytical method development, qualification and validation.Project and risk management for drug development.
Led cross-functional team (analytical, chemistry and formulation) for drug research and development, and CRO services. Preformulation and formulation studies. Development of smart insulin delivery system for diabetes treatment (Liposome (LNP)-agglomerated vesicle as carrier, known as Agglomerated Vesicle Technology or AVT). Gel, microsphere, suspension, solution preformation/formulation studies. Polypeptide sustained release. Eyedrop development.Analytical method development and qualification, stability study and mechanism study. synthesis of polymer conjugate (PEG-conjugate).Project management.
Provide technical and information services to biotechnology, pharmaceutical companies focusing on nanoparticle drug delivery.
Oceanside, Ca, Us
1. Established and developed the formulation process of screening and scaled-up of lipoplex/liposome for siRNA delivery (solid and liquid dosages for in vitro/in vivo bioevaluations). 2. Developed/optimized methods for the characterization of raw material/intermediates, and products (small molecules, polymers, polymer-conjugates, formulation nanoparticles, etc.)3. Wrote SOPs, raw materials and products QC, proposed/established product specifications.4. Synthesis and characterization of Polymer-drug conjugtes (including PEGylation and targeting) for anticancer therapy.6. Implemented the databases to organize the analytical data
Synthesis, purification, identification of small molecule combinatorial libraries.
Synthesis, purification, identification and optimization of inhibitors and their prodrugs of HIV-1 reverse transcriptase and nucleotides.
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Fu Chen is listed as Director of Formulation Development.
AeroLeads has found 2 work email signals at @drugdeliveryexperts.com for Fu Chen.
Fu Chen is based in South San Francisco, California, United States.
Fu Chen has worked for Genprex, Inc., California, Drug Delivery Experts, Guangyuan Huaguang Bioscience, and Nitto Denko Technical Corporation.
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Fu Chen holds Course Certificates And Certified Badge, Project Management, Risk Management from Gale/Library, Edx/Ibdx/Pmi.
Fu Chen is listed with skills including Analytical Method Development And Validation For Characterizations, Efficient Data Management And Statistical Analysis, Instrument Trouble Shooting And Maintenance, Polymer Characterization, Polymer Science/Chemistry, Nanoparticles, Formulation, and Purification.
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