Gabriel Lurz Email and Phone Number

Designed, planned, and executed batch, fed batch, and perfusion experiments in shake flasks, deep well plates, ambr15, ambr250, and benchtop bioreactors with mammalian (CHO & HEK) cell lines. Transferred developed processes to Pilot Plant, Clinical Manufacturing, and Commercial Manufacturing across 3 different internal sites. Supported Person in Plant activities to ensure successful technology transfer in a cGMP suite.Led experiments as a project manager for Process Optimization and Process Characterization of a late stage asset. Decreased historical work package durations from 2-3 years to 6-12 months with the same FTE resources.Improved titers by 50-150% for a mAb and a trispecific mAb in fed batch mode by further developing the media and feed while optimizing the production process and saving $10-$70 million per year of manufacturing costs.Documented work in a ELN and Veeva Vault system authored and reviewed relevant sections of Type C meeting requests and INDs.

Developed a HT cell culture model in the AMBR250 that scaled to the 10L, 200L, and 2000L scale with representative product quality and cell culture performance.Built Raman models for in process control of glucose and amino acidsPresented externally at the Bioprocessing summit to further scientific advancement of integrated continuous bioprocessing development.Executed process optimization and media and feed development work packages. Discovered novel components that improved cell health and batch duration to increase final titers without changing product quality.Acted as Business analyst to deploy an Electronic Lab Notebook. Mapped 5 cell culture processes as a current and to be state. Translated user requirements to user stories for future development.

CHO and HEK process development Raman spectroscopy Digital transformation super user Perfusion and fed batch operations

 Worked in a multidisciplinary team in a competitive start-up environment. Frequently asked to develop and use new skills including machine learning, quality assurance, and investor relations. Developed relationships between the Machine Learning Team, Leadership Team, and Manufacturing Team to ensure implementation of new analytical techniques and equipment  Monitored, operated and troubleshooted X-ray Fluorescence (XRF) and Scanning Electron Microscope (SEM) instrumentation used for data collection on small carbon samples. Organized and performed statistical analysis of the data by using Excel and MATLAB resulting in professional presentations for investors and government agencies. Repeatedly added value by discovering correlations with a coefficient of determination of 0.95 or higher. Process management of analytical process using XRF and SEM. Responsible for ensuring consistent sample preparation standards. Functioned as quality control for sample preparation and identified possible contaminants during the experimental process to identify false-positive and ensure accurate results. Trained and proficient in Radiation Safety, SEM operation, and XRF Operation

-Responsible for 60 students-Designed and executed labs on a weekly basis-Responsible for grading-Held office hours and recitations

- Responsible for experiments using 5L scale bioreactors with Raman Probes.- Sampled bioreactors daily. Troubleshoot and implement solutions to ensure cell culture survival in a cGMP facility.- Presented findings to multidisciplinary groups across sites.- Collaborated with other in groups in process development to support their goals.- Built control systems in DeltaV.- Operated Raman and FTIR machines. Analyzed data generated and built predictive models in Matlab.

- Serves as a member of student on-call duty rotation; responsible for over 50 upperclassmen students- Plans and implements educational, recreational, social, and diverse programs- Counsels residents on personal, academic, and career concerns- Manages administrative duties including maintenance requests, incident reports, and room transfers- Enforces and upholds university policies- Acts as liaison between residents and the Department of Housing and Residential Education- Works as part of a team of 8 Resident Assistants

-Worked in a multidisciplinary team where I was asked to fulfill many roles in a competitive startup enviroment-Quality control-Process management -XRF operation and analysis-SEM operation and analysis-Data organization -Investor and government agencies relations-Statistical analysis