Neha Gaur, Phd

Neha Gaur, Phd Email and Phone Number

Lead Scientist at Helex| Gene Editing | CRISPR - Cas9 @ Helex
Neha Gaur, Phd's Location
Hyderabad, Telangana, India, India
About Neha Gaur, Phd

As the Lead Scientist at Helex, I am responsible for supervising the design and implementation of both in vitro and in vivo studies to validate our proprietary technology concepts. This validation process is crucial for developing safe and effective products for our customers, and I am responsible for establishing the validation of Helex's proprietary safety platform in vitro and in vivo.Aside from my work at Helex, I have made significant contributions to the development of CyGenica's Molecular Nanomachine (GEENIE). This exclusive technology delivers chemotherapeutic drugs, siRNA, and CRISPR toolbox for intracellular delivery. My proficiency in technical skills and designing and implementing efficient workflows have been crucial in ensuring the success of this project.During my postdoctoral research, I focused on investigating Toll-like receptor 2 (TLR2) interactomes in periodontitis caused by Porphyromonas gingivalis. I used CRISPR Cas9 and FACS to examine their impact. Additionally, I studied the endoribonucleolytic activity of the toxin MazF from the highly pathogenic Gram-positive bacteria, Staphylococcus aureus (Sa), and the impact of EDF peptides on this activity.While pursuing my Ph.D., I identified the structure-function relationships of arginase in Leishmania donovani. My expertise in conducting biochemical and biophysical characterisations of arginase allowed me to explore its potential as a drug target for leishmaniasis.My passion is using my skills and knowledge to develop innovative products that have the potential to make a positive impact on people's lives. I am committed to driving scientific advancement and contributing to the development of groundbreaking products.

Neha Gaur, Phd's Current Company Details
Helex

Helex

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Lead Scientist at Helex| Gene Editing | CRISPR - Cas9
Neha Gaur, Phd Work Experience Details
  • Helex
    Lead Scientist
    Helex Aug 2021 - Present
    Hyderabad, Telangana, India
    • Leading Science – designing & executing in vitro and in vivo studies for validating Proof of Concepts for proprietary technology• Established the validation of the Helex proprietary safety platform in vitro and in vivo• Designing & implementing inter and intra-organization workflows
  • Cygenica
    Research Scientist
    Cygenica Aug 2020 - Jul 2021
    Pune, Maharashtra, India
    • Established Proof of Concept for delivery of CRISPR toolbox via CyFect CRISPR Guard enabling genome editing up to 20%• Core team member involved in the development of proprietary Molecular Nanomachine (GEENIE) for intracellular delivery (Chemotherapeutic drugs, siRNA, CRISPR toolbox)• Designed, cloned, and characterized chimeric/fusion proteins• Formulated and standardized experimental protocols, laboratory standard operating procedures (SOPs)• Mentored junior members of the R&D team and supervised their daily research activities
  • The Hebrew University Of Jerusalem
    Postdoctoral Researcher
    The Hebrew University Of Jerusalem Mar 2017 - Sep 2019
    • Investigated the interactomes of Toll-like receptor 2 (TLR2) in periodontitis caused by Porphyromonas gingivalis using CRISPR Cas9, FACS• Examined the effect of the EDF (Extracellular Death Factors) peptides on the endoribonucleolytic activity of the toxin MazF of highly pathogenic Gram-positive bacteria, Staphylococcus aureus (Sa)

Neha Gaur, Phd Education Details

Frequently Asked Questions about Neha Gaur, Phd

What company does Neha Gaur, Phd work for?

Neha Gaur, Phd works for Helex

What is Neha Gaur, Phd's role at the current company?

Neha Gaur, Phd's current role is Lead Scientist at Helex| Gene Editing | CRISPR - Cas9.

What schools did Neha Gaur, Phd attend?

Neha Gaur, Phd attended Csir-Central Drug Research Institute, Lucknow, Chhatrapati Shahu Ji Maharaj University, Deen Dayal Upadhyay Gorakhpur University, Gorakhpur.

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