Gustavo Gozzi Email & Phone Number

Toulouse Area, France

Missions:- Manage a compound management team;- Ensure the management of activities (preparation and distribution of compounds as part of the team's activities);- Follow the performance indicators of the team;- Manage transversal interactions with other Evotec departments;- Manage customer relationship;- Perform a technological and scientific watch;- Lead projects of continuous improvement, which can benefit from the tools of lean methodology;- Perform the activities in compliance with applicable quality procedures, as well as in compliance with the rules of hygiene, safety, security and environment;- Ensure the respect of the contract commitment to key deliverables / milestones delivery, internal and external resources, budget and timelines, while ensuring high scientific quality;- Manage the internal communication (reporting) and external communication, the relationship with the client related to the project, in relation to business development and the alliance management when appropriate;- Ensure quality and reliability of results;- Ensure good laboratory practices and health and safety instructions;

Dijon Area, France

Objective: - Development of protein inhibitorsResponsibilities and development:- Project management - Planning and execution of experiments - Data analysis - Written of scientific reports/papers- Oral communications (English and French) - Scientific monitoring Results: - Discovery of the first HSP110 chemical inhibitor- 2 publications - 1 patent Technical Skills:- Screening of chemical compounds (based on cell functional or in vitro assays); protein-compound and protein-protein interactions (biolayer interferometry-Octet, immunoprecipitation, alphascreen); cytometry (proliferation and cytotoxicity); cell culture; bioluminescence assays; western blotting.

Lyon Area, France / Curitiba, Brazil

Objectives: -Drug discovery and SAR of compounds for ABCG2 inhibition Results: -A new class of molecules discovered and improvement of existing compounds, 8 papers.Responsibilities and development:- Project management - Planning and execution of experiments - Data analysis - Written of scientific reporters and papers - Scientific monitoring Technical Skills:- Screening of chemical compounds (cell functional and in vitro-based); structure-activity relationship studies; cytometry (cytotoxicity, protein identification, drug accumulation); eukaryotic cell culture (cell lines), ATPase activity of ABC transporters.

Curitiba Area, Brazil

Objective: To evaluate cytotoxicity and selectivity of molecules on liver tumor cells. Accomplishments: 1 compound evidenced for commercialization in R&D, 4 papers.General Responsibilities:- Writing of funding application, - Written of technical reports,- Presentation of results, - Training of a master and a PhD student in cell culture. - Lectures.Technical responsibilities:- Cell viability/cytotoxicity (Flow cytometry, MTT, LDH, Crystal violet),- Primary (Hepatocytes) and cell lines culture,- Antioxidant enzymes activities (spectrophotometry and spectrofluorimetry),- Fluorescence microscopy (AnnexinV, PI, DAPI), - DNA electrophoresis.

Curitiba Area, Brazil

Objective: - To evaluate the effect of antitumor compounds on mitochondrial functions Responsibilities and development:- Project management- Planning and execution of experiments - Data analysis - Written of scientific reporters and paper - Lectures - Scientific monitoring Results: - 1 Paper published as first author Technical Skills:- Mitochondria isolation, respirometry, spectrophotometric and spectrophotometric-based (membrane permeability transition pore, lipoperoxidation, calcium transport, NAD(P)H oxidation, scavenger activity)

Londrina Area, Brazil

Objective: To quantify mycotoxins in animal food.Accomplishments: Knowledge of HPLC use and ELISA development.

Doctor Of Philosophy - Phd, Pharmaceutics And Drug Design

Doctor Of Philosophy - Phd, Biochemistry

Master'S Degree, Biochemistry

Bachelor Of Pharmacy - Bpharm