Pat Brady Email and Phone Number
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Self-driven computational scientist and action-oriented doer with 20+ years of pharma experience defining data & computational strategy, developing custom computational infrastructure and directly impacting therapeutic programs • Led a small team of Ph.D. computational chemists for ~20 years to impact drug discovery via infrastructure development & applied computation and analytics• Led the Screening Analytics SIG in GSK for 14 years and coordinated analytics support for the global HTS portfolio• Led an educational program in GSK that has provided pragmatic data science training to hundreds of Discovery scientists over 6 years • Provided direct computational support for over 50 therapeutic projects in hit identification, hit to lead, and lead optimization phases • Developed and deployed dozens of custom cheminformatics and computational chemistry domain-focused applications in support of drug discovery programs and initiatives in GSKFull CV available upon requestComp Sci Expertise: Analytics automation; biological fingerprints & target/assay clustering; chemical clustering & diversity sampling; cheminformatics, data acquisition & manipulation; data visualization; hit triage; library enumeration & multi-objective combinatorial library design; molecular docking; molecular superposition; pharmacophore fingerprints; protein binding site mapping; relational databases (oracle, mysql, dbm); scientific software development; software engineering & web deployment; screening analytics (HTS, ASMS, DEL, FBS, CETSA); structure-based design; teaching & hands-on data science instruction; virtual screening for scaffold hopping (3D & 2D) and SAR hit expansion (2D)Software: Tibco Spotfire (visualization); RDKIT; CCG software (MOE, Pharmacophore searching); OpenEye tools (FastROCS/ROCS, Omega, OEChem); Chemaxon tools; Schrodinger software (Maestro, Glide).Languages: python, perl, c++/c, php, SQL (mysql, oracle), CUDA (c) Systems: Fluent in unix (linux, irix) and windows operating systems; experienced in cpu/gpu cluster computing & queueing (slurm, sge, & lsf queuing)
Kymera Therapeutics
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Senior Director, Computational ChemistryKymera Therapeutics Jun 2022 - PresentWatertown, Ma, Us -
Associate DirectorGsk Dec 2021 - Jun 2022Brentford, Middlesex, Gb -
Scientific Team LeaderGsk Jun 2011 - Dec 2021Brentford, Middlesex, Gb -
InvestigatorGsk Jan 2003 - Jun 2011Brentford, Middlesex, Gb -
Senior Research InvestigatorBristol Myers Squibb Oct 2001 - Nov 2002Lawrence Township, Nj, Us -
Senior Research ScientistDupont Pharmaceuticals Jul 1999 - Oct 2001Us -
Postdoctoral ScientistDupont Pharmaceuticals Jul 1998 - Jul 1999Us -
Postdoctoral ScientistDupont Merck Pharmaceutical Co Aug 1997 - Jul 1998
Pat Brady Skills
Pat Brady Education Details
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University Of PennsylvaniaPhysics -
James Madison UniversityMathematics And English
Frequently Asked Questions about Pat Brady
What company does Pat Brady work for?
Pat Brady works for Kymera Therapeutics
What is Pat Brady's role at the current company?
Pat Brady's current role is Computational chemist, cheminformatician and dogged problem solver with 20+ years of pharma experience in data analytics & computational science.
What is Pat Brady's email address?
Pat Brady's email address is pa****@****gsk.com
What schools did Pat Brady attend?
Pat Brady attended University Of Pennsylvania, James Madison University.
What skills is Pat Brady known for?
Pat Brady has skills like Drug Discovery, Pharmaceutical Industry, Drug Development, Drug Design, Lifesciences, Science, Enzyme Kinetics, Product Development.
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