HoD for two busy Operations groups, utilising physicochemical methods for analysis of biotherapeutic molecules.Responsible for ensuring the smooth running of these departments and meeting financial targets, line-manager to seven full-time staff

Responsibility for day-to-day running of thirteen laboratories to ISO13485 regulatory standard; the laboratories are developing diagnostic kits for the rapid detection of various types of infectious diseases using molecular biological & spectroscopic techniquesOversight of receipt, QC testing and release of incoming goods, materials and consumables; calibration/validation of all equipment used; ongoing maintenance of all laboratories to ISO 13485 standard (this was obtained in October… Show more Responsibility for day-to-day running of thirteen laboratories to ISO13485 regulatory standard; the laboratories are developing diagnostic kits for the rapid detection of various types of infectious diseases using molecular biological & spectroscopic techniquesOversight of receipt, QC testing and release of incoming goods, materials and consumables; calibration/validation of all equipment used; ongoing maintenance of all laboratories to ISO 13485 standard (this was obtained in October 2012)Dealing with suppliers and vendors to obtain best service and prices, implementation of supply agreements and contractsImplementation of supplier evaluation system and ERP/manufacturing softwareSupervision of staff and training of new starts and refresher training on laboratory contamination procedures, safety and generation of works ordersResponsible for divisional Health & Safety, overseeing COSHH, biological safety, GMO policies and laser safety: preparation and review of policies, performing regular inspections, training of staff and chemical/biological waste disposal Show less

Responsible for running of a GMP laboratory which performs lot release and stability studies for drug products and biologicals. Line manager for four full time staff.Implementation and optimisation of ‘on time delivery’ and ‘right first time’ initiatives within the Analytical Chemistry group.Responsible for chemical safety training and safe storage/disposal of materials at the BioReliance site in Glasgow, UK and for implementation of new COSHH assessment… Show more Responsible for running of a GMP laboratory which performs lot release and stability studies for drug products and biologicals. Line manager for four full time staff.Implementation and optimisation of ‘on time delivery’ and ‘right first time’ initiatives within the Analytical Chemistry group.Responsible for chemical safety training and safe storage/disposal of materials at the BioReliance site in Glasgow, UK and for implementation of new COSHH assessment system.Responsible for introduction of partnership with an analytical services company in an effort to increase the services offered to clients and to expand the existing client base. Business development role, visiting clients with Sales staff in an effort to win additional business. The departmental literature/handouts available to clients have been extensively upgraded to reflect the positive changes and to better aid Sales staff to sell the service offered. Show less

Senior Scientist in laboratory performing lot release testing and stability studies for phase III and licensed products. This utilised a range of analytical techniques including HPLC, peptide mapping, residual moisture analysis and particle size analysis.Responsibility for day-to-day supervision of staff members, scheduling tasks, training and staff appraisals. Charged with ensuring all projects are carried out efficiently and within agreed timelines and budget.Carrying out… Show more Senior Scientist in laboratory performing lot release testing and stability studies for phase III and licensed products. This utilised a range of analytical techniques including HPLC, peptide mapping, residual moisture analysis and particle size analysis.Responsibility for day-to-day supervision of staff members, scheduling tasks, training and staff appraisals. Charged with ensuring all projects are carried out efficiently and within agreed timelines and budget.Carrying out COSHH assessments of all of the chemicals/biologicals used and performing risk assessments of all analytical procedures. Show less

Managed a laboratory performing purification processes to validate for the removal of viruses and TSEs, utilising a number of chromatographic (HPLC, FPLC and column chromatography), filtration, inactivation and fractionation procedures. Products analysed include those produced from blood, various organs/tissues and by biotechnology techniques.Responsibility for day-to-day supervision of 17 members of staff, scheduling tasks and ensuring all projects are completed within the agreed… Show more Managed a laboratory performing purification processes to validate for the removal of viruses and TSEs, utilising a number of chromatographic (HPLC, FPLC and column chromatography), filtration, inactivation and fractionation procedures. Products analysed include those produced from blood, various organs/tissues and by biotechnology techniques.Responsibility for day-to-day supervision of 17 members of staff, scheduling tasks and ensuring all projects are completed within the agreed timeframe.Directed validation projects from initial client enquiry, through study design and experimental work to completion of project, involving supervision of full-time staff in all laboratory /administrative work. Show less

Organised provision of analytical services to industry (BASF) with 24-hour turnaround. This included recording of Nuclear Magnetic Resonance (NMR) spectra (1H, 13C) and interpretation, Mass Spectroscopy, elemental analysis and Gas Chromatography (GC) as required.Lead small research group in the synthesis of pseudopeptide analogues of thyrotropin releasing hormone (TRH) by solution-phase methods, and their subsequent conformational analysis, testing for biological stability and binding… Show more Organised provision of analytical services to industry (BASF) with 24-hour turnaround. This included recording of Nuclear Magnetic Resonance (NMR) spectra (1H, 13C) and interpretation, Mass Spectroscopy, elemental analysis and Gas Chromatography (GC) as required.Lead small research group in the synthesis of pseudopeptide analogues of thyrotropin releasing hormone (TRH) by solution-phase methods, and their subsequent conformational analysis, testing for biological stability and binding assays.Investigated the study of degradation mechanisms in polyolefin films by a number of spectroscopic techniques including thermal analysis, FTIR and NMR.Analysed the protein metabolism in patients suffering from diseases of muscle wastage by identifying nucleotide markers excreted in urine using HPLC and NMR. Show less

Managed Faculty High-Field NMR Centre, consisting of 300 MHz and 500 MHz instruments, providing multinuclear and multidimensional spectra for researchers within different departments and disciplines.Produced by solid-phase synthesis, and purified to homogeneity, a number of peptide inhibitors of the enzyme renin. Determined the solution phase structures, designed biologically active conformationally constrained analogues and carried out enzyme binding assays.Planned and carried… Show more Managed Faculty High-Field NMR Centre, consisting of 300 MHz and 500 MHz instruments, providing multinuclear and multidimensional spectra for researchers within different departments and disciplines.Produced by solid-phase synthesis, and purified to homogeneity, a number of peptide inhibitors of the enzyme renin. Determined the solution phase structures, designed biologically active conformationally constrained analogues and carried out enzyme binding assays.Planned and carried out the synthesis and characterisation of fragments from the IgE receptor of up to 85 amino acids in length, applying techniques such as High Performance Liquid Chromatography (HPLC), gel electrophoresis and isoelectric focusing. These fragments were subsequently subjected to conformational analysis in a bid to synthesise rationally designed non-peptidic analogues with biological activity. Show less