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Experienced leader in biophysical/biochemical characterization of a wide variety of biologic pharmaceuticals.
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Principal ScientistPfizer Aug 2023 - PresentNew York, New York, Us(Formerly SeaGen)Develop stable drug substance and lyophilized drug product for early stage antibody drug conjugate (ADC)Lead cross-functional process development team to deliver GMP capable manufacturing process. Mentor junior scientists -
FounderLux Natura Photography Jun 2022 - Presentwww.LuxNaturaPhoto.comServices: Fine art printsLicensing images for print and/or advertisingTravel photography services. Including back country expeditions. I am NOLS trained and comfortable in extreme locations.Portraits. Specializing in action portraitureAutomotive photo shoots. Preparation of advertisement for sale. High quality photos bring the best sale prices!Photo retouching. Improving your own photos to make them pop. Event PhotographyPhotographer's assistant
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Senior ScientistNovartis Gene Therapies Aug 2019 - Oct 2022Basel, Baselstadt, Ch(Formerly Avexis)The central role of my position is to support the development of next generation AAV gene therapy manufacturing processes by providing critical analytic data. In addition, my team and I are developing and implementing new assays to improve process and product understanding. I have been involved in many start-up activities establishing process and analytic development labs at the new North Carolina site. These roles have included contributions to: laboratory space planning, instrumentation ordering and installation, hiring a growing team of scientists, and creating business processes to encourage the collaborative flow of data across several sites. -
Senior Research AssociateGenentech Jun 2012 - Jul 2019South San Francisco, California, UsLate Stage Pharmaceutical DevelopmentPrimarily focused on product stability through formulation development of pre-BLA biologic pharmaceutical products. Additional techniques: Sub-visible particle characterization (HIAC, Coulter Counter), Color determination, Excipient quantitation/ characterization, Osmolality, Hydrophobic interaction chromatography (HIC) -
Research Associate IiiRegeneron Pharmaceuticals Aug 2008 - May 2012Tarrytown, New York, UsIn the protein biochemistry group I characterized various protein based therapeutics. My research contributed to lead drug selection, IND filing, process comparability, and BLA filing. Additionally I purified, characterized and performed labeling of various protein based reagents to support GLP bioassay requirements. Techniques include: SDS-PAGE, Western Blot, Two Dimensional PAGE, Isoelectric Focusing (IEF), ELISA, Size Exclusion Chromatography (HPLC, and UPLC), Affinity Chromatrography, Capillary Electrophoresis (CE-SDS and cIEF), and Light Scatter (MALLS). -
Research TechnicianColorado State University Mar 2005 - Jul 2008Fort Collins, Co, UsLuger LaboratoryI started as an undergraduate research assistant and continued to complete my masters degree focusing on the binding interactions between Histone complexes and the chaperone NAP1.Techniques include: sub-cloning, protein expression, protein purification, medium scale DNA expression and purification, fluorescence spectroscopy, protein-DNA complex reconstitution.
Greg Downing Skills
Greg Downing Education Details
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Colorado State UniversityBiochemistry -
NolsPatagonia Mountaineering -
NolsAlaska [Arctic] Brooks Range Backpacking
Frequently Asked Questions about Greg Downing
What company does Greg Downing work for?
Greg Downing works for Pfizer
What is Greg Downing's role at the current company?
Greg Downing's current role is Principal Scientist, Pharmaceutical Sciences.
What is Greg Downing's email address?
Greg Downing's email address is do****@****ene.com
What schools did Greg Downing attend?
Greg Downing attended Colorado State University, Nols, Nols.
What skills is Greg Downing known for?
Greg Downing has skills like Protein Purification, Protein Chemistry, Biochemistry, Western Blotting, Elisa, Purification, Hplc, Size Exclusion, Protein Characterization, Sds Page, Capillary Electrophoresis, Gel Electrophoresis.
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