Gregg Wesolowski Email & Phone Number

Highly collaborative research biochemist with expertise in assay development directed toward development of novel AAV gene therapy vectors, as well as discovery and development of small molecule therapeutics in the areas of osteoporosis, osteoarthritis and oncology. Broad range of experience in pre-clinical lead optimization programs including screening, biomarkers, mechanism of action studies, in-vivo efficacy, target engagement and safety studies.Specialities: • Cell-based assay development and validation • ELISA and RIA-based biomarker analyses• Isolation and culture of primary bone marrow, tumor tissue, mammalian cell lines, immortalization and cloning• Electrophoresis, Western blotting, immunoprecipitation, protein assays, phosphorylation • Microscopy - phase contrast, fluorescence, polarized light• Enzyme inhibition, covalent labeling with radioligands• Autoradiography• Micro-computed tomography • In vivo studies - animal handling, necropsy, tissue harvest/drug distribution, dosing, and

Listed skills include Drug Discovery, Biotechnology, Lifesciences, Pharmaceutical Industry, and 11 others.