Greg Goldmacher Email & Phone Number

Boston, Ma, Us

• Medical, scientific, and operational leadership for clinical imaging, clinical pathology, and biomarker-based endpoint assessments in clinical development, leading a team of 24 physicians and scientists; overseeing ~300 clinical trials (phases I-IV, along with investigator-led studies); supporting regulatory filings, meetings, and inspections. Immunotherapy and targeted therapy focus in oncology, including heme, GI, GU, GYN, thoracic, skin, head/neck, and CNS cancers; also supporting neurological, cardiovascular, endocrine, immunology, and infectious disease trials • Business development: leading integration of Harpoon Therapeutics, and support integration of other acquired companies into Merck Research Laboratories, overseeing integration of talent, data, assets, ongoing preclinical and clinical programs; support due diligence for M&A; commercial partnerships on AI and biomarker research; S&E in novel therapeutic modalities• Oversee outsourcing of central imaging and pathology, with procurement, vendor management, and quality monitoring• Support internal VC funds with S&E and relationship management for strategic investment in enabling technologies, in a role similar to a venture partner• Merck Digital Science Studio (startup incubator) steering committee, providing selected startup with funding, space, brand and network development, and investor engagement• Created and lead (matrix) a multidisciplinary team driving artificial intelligence and novel endpoint research, including clinical and translational imaging, statistics, data science, clinicians, and business development• Oversee operational improvement initiatives with departments across the organization (data management, statistics, clinical science, study management, field operations, compliance, regulatory, and others) • Develop and conduct training for internal and external teams on clinical trial endpoints, imaging, data management, scientific communication, and presentation skills

Philadelphia, Pa, Us

Co-working space and support services that allow physicians and other healthcare providers to practice on their own terms and on their own schedule.

Dublin, Ie

• Medical and scientific leadership for independent outcome evaluation (imaging and clinical endpoint assessments) in over 100 clinical trials, in phases I-IV• Head of Oncology Imaging; other therapeutic areas include neurology/CNS, cardiovascular disease, rheumatology, infectious disease, and diagnostic agent development• Developed trial protocols, imaging charters, case report forms, and other trial documents• Wrote journal articles, guidance documents, educational, and marketing materials• Supported sales and marketing with proposal development, bid defenses, and webinars• Traveled globally to present at meetings of investigators, industry decision makers, academic experts, and other stakeholders• Ran internal research projects, published and presented in commercial and academic settings• Built relationships with academic opinion leaders and strategic clients• Supported clinical operations during study startup and execution• Performed independent review in oncology and other trials, using a variety of response criteria (RECIST, RANO, Cheson, volumetrics, and others)• Trained independent readers, investigators, site radiologists, and study staff throughout the world; create educational materials for ICON staff and trial sponsor teams• Responsible for up to 50 projects at a time, led teams of up to 10 per project (matrix), and received direct reports• Member of several international collaborative interdisciplinary groups of thought leaders driving advances in brain tumor imaging and treatment response assessment

Dublin, Ie

Dublin, Ie

Dublin, Ie

Philadelphia, Pa, Us

• Research on stem cell therapy for ischemic stroke, using small animal surgery and imaging • Wrote regulatory protocols, academic manuscripts, and patent documentation

Boston, Ma, Us

• Physician co-investigator and research manager for NIH-funded research projects on advanced stroke imaging• Trained physicians and staff for clinical trial roles; supervised screening and enrollment; designed case report forms; collaborated with IT on data flow; evaluated adverse events; analyzed data using imaging and statistical software• Developed a stroke imaging case database for prospective and retrospective analyses• Participated in development and early testing of a novel imaging device (Electrical Impedance Spectroscopy), including grant applications, IRB approval, instrument design, prototype construction, and early clinical testing• Ran imaging core lab for industry-sponsored phase 2A clinical trial: data quality and site protocol compliance, CRF design and implementation, ran independent review and prepared results for investigators and sponsor• Presented reports at national conferences; wrote grant proposals, IRB protocols, and manuscripts

New York, Ny, Us

• Taught courses and trained teachers in SAT, MCAT, USMLE Step I• Site manager and training administrator for many courses and training events• Wrote and edited MCAT and USMLE Step I preparation materials• Aided in marketing and course development for MCAT and USMLE Step I

Md, Phd, Medicine / Neuroscience

Mba

Professional Certificate, International Management

Ba, Biological Sciences