Gretchen Unger Email and Phone Number
Gretchen Unger work email
- Valid
- Valid
- Valid
Gretchen Unger personal email
Gretchen Unger phone numbers
Founder of Surtovol Laboratories and GeneSegues with the overarching goal of enabling new classes of therapeutics through advanced drug delivery. 25 years of experience leading and executing novel particle formulation, process design and manufacturing scaleup strategies. Applying expertise in material science, cell biology and pharmacology to capitalize on drug delivery advantages at the biologically-relevant sub-50 nanometer threshold. Pioneering new cell targeting strategies with the nanocapsule's modular crystalline shell that readily incorporates virtually any nucleic acid cargo and targeting protein or other desired targeting molecule. Building upon previous experience in industrial coatings industry to successfully scale the nanocapsule technology. Passionate about bringing technology from bench to bedside.
Surtovol Laboratories, Inc.
View-
Chief Scientific Officer At Surtovol Laboratories, Inc.Surtovol Laboratories, Inc.Saint Paul, Mn, Us
-
Member, Masonic Cancer Center, Chemoprevention SectionMasonic Cancer Center, University Of Minnesota Oct 2023 - PresentMinneapolis, Minnesota, Us
-
Chief Scientific Officer At Surtovol Laboratories, Inc.Surtovol Laboratories, Inc. Mar 2022 - PresentSurtovol is a dba company of GeneSegues, focused on developing novel sub-50 nanometer (s50) capsule technology for ligand-directed drug delivery to hepatic as well as extra-hepatic tissue. We outlicense s50 technology to partners developing new therapeutic candidates to create next-generation therapies, particularly in the fields of RNA and pDNA drugs. s50 is differentiated in part by its novel size and structure that enables extrahepatic targeting as well as cell uptake via non-degradative caveolae pathways, similar to viruses such as SV-40.Key accomplishments:• Discovered, patented and developed stabilized micelle, co-crystallization nanocapsule chemistry for cell and organ-specific non-viral delivery of nucleic acids, contrast and small molecules via IV, subcutaneous, inhalation, and passive topical routes.• Early adopter and ongoing optimizer of 3D cell culture methods, crucial to proper understanding of endosome-avoiding, lipid-raft trafficking s50 capsules.• Successfully scaled chemistry and process from 125 ug to 144 mg to support studies inrodents, rabbits, weanlings pigs, and companion felines.• Led GMP scaleup of recombinant protein for proprietary s50 tumor-targeting ligand.• Advanced analytical methods and solid-state characterization of novel solid dosage form toward GMP scaleup.• Developed novel cold isotopic method for in vivo biodistribution based on NAA. • Demonstrated tumor-targeted checkpoint inhibition for lead compound in oncology.• Expanded and further tested s50 capsule chemistry to include mRNA, RNP and other unique CRISPR constructs, protein therapeutic and microscopy reagent cargos.• Recruited, trained and led interdisciplinary laboratory team of staff and consultants.• Authored or co-authored more than 30 journal articles and conference posters, inventor on 15 patent applications, and Principal Investigator or key collaborator on 19 awarded SBIRs and other federal and state grants and contracts.
-
Chief Scientific OfficerGenesegues, Inc. Jan 2003 - Present
-
Chief Scientific OfficerRovermed Biosciences, Llc Jan 2017 - Feb 2018RoverMed was spun out of GeneSegues in 2017 to focus on partnering s50 technology with larger drug developers to create new therapies, while GeneSegues focused on developing proprietary cancer drugs using s50 technology. The spinoff strategy ended in 2020 and s50 capsule development is housed under GeneSegues.Key Accomplishments:• Coordinated, designed, executed, analyzed, problem solved, and communicateddetails and results of in vivo pilot studies with larger pharma partners, typically withmultiple studies running simultaneously.
-
Adjunct Asst. Professor,University Of Minnesota, Dept. Of Laboratory Medicine. Jun 2003 - Dec 2006
-
Nat'L Research Service Award FellowUniversity Of Minnesota, Dept Of Otolaryngology May 2000 - May 2002
-
Research AssociateMinneapolis Medical Research Foundation Aug 1996 - May 2000Minneapolis, Mn, Us• Developed multiple assays to quantify angiogenesis and wound healing in an irradiated porcine model.• Formulated oral dosage form to manage stress response of porcine research subjects.• Developed nanocapsule dosage form for topical delivery of plasmid DNA.• Skill areas include: DOE, electrophoresis, conventional histology, cytospins, ELISA, semi-quantitative PCR, in situ hybridization, RNAse protection, transfection, immunoprecipitation, western blotting, tissue mechanical properties, primary and lymphocyte cell isolation, veterinary anesthesia, ear catheterization (porcine) and GLP certification. -
Research Assistant, Pharmacology,University Of Minnesota, Dept Of Pharmacology Jun 1992 - Jun 1997Developed functional cell test to quantify adhesion development and kinetics of cells reattaching after wounding. • Thesis title: Calcium-sensitive acceleration of wound closure in mechanically wounded endothelial cells.• Skill areas: sterile tissue culture, microinjection, Fura-2 calcium imaging, interference reflection microscopy, atomic force microscopy, confocal immunofluorescence, quantitative image analysis, phase contrast microscopy, physiology, pathobiology, cardiovascular & CNS physiology.
-
Sr. Materials EngineerDatacard Corp., Minnetonka, Mn 1989 - 1992Team member in Corporate Technology group supporting new product and materials development on a corporate basis. • Developed high performance water-borne magnetic media for increased reliability as a plastic card magnetic stripe and a water-borne topcoat for added durability. This invention overcame problems of poor substrate adhesion and good coating performance common to water-borne products.- Completed materials characterization of ribbon and receptor materials used in dye-diffusion thermal transfer printing. This information was used for specification and QC development.• Developed formulation and process method to manufacture a consistent amorphous calendared vinyl for credit card substrate.• Established thermal analysis laboratory; supervised technicians. ¬¬¬¬• Skill areas: DSC, TMA, TGA, Rheological techniques, ESCA, FTIR, CRO management, customer/stakeholder engagement.
-
Chemical EngineerDatacard Corporation 1987 - 1989Team member in Corporate Technology group focused on correlating fundamental material properties with practical product requirements. • Developed raw material specifications for the card manufacturing division.• Represented Operations in vendor certification and negotiations. • Developed water-borne mass transfer thermal transfer print ribbon.• Developed statistical model utilizing experimental data to relate physical design parameters to performance for optimized credit card magnetic striping. Involved significant use of DOE.• Developed water-borne adhesive printing ink, water-borne laminating adhesives, and outer plastic film laminates for use in manufacturing.• Skill areas: Problem-solving, process troubleshooting, new product development, process scaleup, manufacturing engineering (preceding assignments), SPC, formulation, surfactants, Systat. -
Process EngineerDatacard Corporation Mar 1985 - 1987Process Engineer in the manufacturing division for transaction and other plastic cards. - Developed statistical model utilizing experimental data to relate physical design parameters to performance for optimized credit card magnetic striping. Involved significant use of DOE.- Formulated a patent-pending water-borne adhesive printing ink for use in the California manufacturing facility for an annual cost savings of $ 200 K.- Developed a water-borne laminating adhesive for use in contract manufacturing. - Developed formulation and production method for improved outer plastic film laminate.- Specified, purchased and installed equipment for a materials testing laboratory.
-
Sales Support EngineerIxi Laboratories, Hopkins, Mn 1984 - 1985Support Engineer for quality control equipment manufacturer in the magnetic media industry. General responsibilities included: sales support, field support, product promotion and liaison between marketing and R&D teams.
-
Process EngineerE. I. Dupont De Nemours 1982 - 1984
Gretchen Unger Skills
Gretchen Unger Education Details
-
University Of MinnesotaPharmacology -
The University Of KansasChemical Engineering
Frequently Asked Questions about Gretchen Unger
What company does Gretchen Unger work for?
Gretchen Unger works for Surtovol Laboratories, Inc.
What is Gretchen Unger's role at the current company?
Gretchen Unger's current role is Chief Scientific Officer at Surtovol Laboratories, Inc..
What is Gretchen Unger's email address?
Gretchen Unger's email address is gm****@****ues.com
What is Gretchen Unger's direct phone number?
Gretchen Unger's direct phone number is +161224*****
What schools did Gretchen Unger attend?
Gretchen Unger attended University Of Minnesota, The University Of Kansas.
What are some of Gretchen Unger's interests?
Gretchen Unger has interest in Exercise, Home Improvement, Reading, Sports, Cooking, Gardening, Outdoors, Electronics, Crafts, Music.
What skills is Gretchen Unger known for?
Gretchen Unger has skills like Biotechnology, Drug Delivery, Lifesciences, Cell Culture, Drug Development, Technology Transfer, Molecular Biology, Cell Biology, Tissue Engineering, Biomaterials, Pharmaceutical Industry, Cell.
Free Chrome Extension
Find emails, phones & company data instantly
Aero Online
Your AI prospecting assistant
Select data to include:
0 records × $0.02 per record
Download 750 million emails and 100 million phone numbers
Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.
Start your free trial