• Nectin is developing monoclonal antibodies for novel immune checkpoin targets relevant for cancer immune therapy• The lead Ab is at an early development stage• I have overall responsibility for all activities related to the lead project and future pipeline, including planning, execution and conclusion drawing, keeping the timelines and budget, and problem solving in real time• I oversee R&D activities done internally as well as by collaborators and CRO abroad

• Quiet was developing a nano-particle platform, called GAGomers, for targeted delivery of anti-cancer drugs • I led the development of Quiet’s lead candidate during preparations for pre-IND and initiation of IND enabling studgies • I was the Israeli top manager and served as a site GM. I was also involved in leading subjects like budget, IP, strategy setting, etc.

• Director, leading Phase 1 and pre-clinical projects, in cancer and cognition• Overall reasonability for all activities related to the project until final submission, in terms of planning and execution, keeping the timelines and budget, and problem solving in real time • Matrix management of different professional unites and activities that are involved in the project such as regulatory aspects, pre-clinical tasks, CMC development, bio-analytical support, clinical development, patent issues, etc.• Working in a global environment; the teams I manage are located in the US, Israel and EU

• Director, leading biosimilar projects focusing on antibody development• Overall reasonability for all activities related to the project until final submission, in terms of planning and execution, keeping the time lines and budget, and problem solving in real time • Matrix management of different professional unites and activities that are involved in the project such as regulatory aspects, pre-clinical tasks, CMC development, bio-analytical support, clinical development, patent issues, etc.• Working in a global environment; the teams I manage as well as my supervisors come from different countries in EU and the US• Working in a partially defined regulatory environment and having to constantly adjust to regulatory changes

• Senior Manager leading innovative pre-clinical projects in the field of cancer, autoimmunity and inflammation from early proof-of-concept steps to regulatory submission• Overall reasonability for all activities related to pre-clinical projects. Taking care of assay planning, execution and conclusion drawing, monitoring budgets and time lines • Matrix management of different professional unites and activities, especially those that concern pharmacology, toxicology and safety, ADME-PK (both in vivo and in vitro assays for all of these activities), as well as the manufacturing of small molecules and proteins up to GMP-grade material• Taking part in sourcing teams which examine pre-clinical and clinical projects for Teva to in-license• Exposure to many novel projects originating from all over the globe, aiming to treat various indications, and employing diverse verity of treatment approaches ranging from small molecules with validated targets all the way to novel targets and cutting edge technologies• Routinely working with people outside Israel; from Teva, from smaller innovative companies, and from commercial research organizations

Post Doc at the lab of Dr. Jason Cyster, Dept. of Immunology.• Research work focused on the role of chemokines in B lymphocyte compartmentalization and function in the spleen. It involved working with various mouse models, as well as employing a variety of ex vivo and in vitro methods• Working with Dr. Cyster, one of the leading researchers in leukocyte migration, I have acquired in-depth knowledge in this field• My work was published in two high-profile papers at Nature Immunology

• Thesis research focused on the role of blood flow, chemokines and integrins in leukocyte migration across endothelial barriers• I developed an in vitro model to mimic and study human leukocyte interactions with inflamed blood vessels• My work was published in two high-profile papers