Guy Bar-Klein Email & Phone Number

Walnut Creek, California, Us

Walnut Creek, California, Us

Walnut Creek, California, Us

Chevy Chase, Maryland, Us

• Investigated novel approaches/potential treatments for genetic diseases of the central nervous system and connective tissues, neurodegenerative and neuromuscular disorders, cerebrovascular lesions, aortic root aneurysms and aortic valve defects.• Identified novel treatments for the prevention of proteins aggregation and dysfunctional autophagy in spinocerebellar ataxia 3.• Established and implemented innovative AAV-based neuromodulation treatment for epilepsy in collaboration with external groups.• Modified critical tissue clearing technics used in neuroscience, introduced and adapted them for compatibility with cardiac tissue and vasculature.• Developed and introduced a creative new approach for imaging large volume, intact cardio-vascular tissues.

Baltimore, Md, Us

• Investigated novel approaches/potential treatments for genetic diseases of the central nervous system and connective tissues, neurodegenerative and neuromuscular disorders, cerebrovascular lesions, aortic root aneurysms and aortic valve defects.• Identified novel treatments for the prevention of proteins aggregation and dysfunctional autophagy in spinocerebellar ataxia 3.• Established and implemented innovative AAV-based neuromodulation treatment for epilepsy in collaboration with external groups.• Modified critical tissue clearing technics used in neuroscience, introduced and adapted them for compatibility with cardiac tissue and vasculature.• Developed and introduced a creative new approach for imaging large volume, intact cardio-vascular tissues.

• Promoted to positions of increasing authority and responsibility due to exemplary performance and strong scientific knowledge. • Developed essential predicting strategies and biomarkers for post-traumatic epilepsy, enabling diagnosis of at-risk patients and monitor the efficacy of various therapies with 92.86% success rate.• Designed clinically relevant MRI-based diagnostic and pharmacodynamic biomarkers for epileptogenesis.• Spearheaded an innovative translational research project for discovering new therapies and improving treatment protocols for preventing neurological complications following poisoning.• Directed and supervised a multinational, multi-disciplinary team of up to 14 experts within smaller groups, leading projects as the first author to an extensive publishing record in high impact journals.

• Created and implemented innovative lesson plans for providing frontal teaching and laboratory instruction for various courses such as human physiology for 255 bio-medical engineering, pharmacy and medical laboratory sciences students and neural basis of cognition for ~30 graduate students.• Conducted office hours for students to provide extra assistance and review exams, driving optimal student achievement.• Actively engaged in various professional meetings, educational conferences and teacher training workshops to maintain and improve professional competence.

• Investigated leading mechanisms for post-injury epilepsy and potential preventive therapies employing biochemical assays, video-EEG monitoring and imaging techniques.• Identified key factors in the development of epilepsy and designed a first-in-class preventive treatment for epileptogenesis.• Mentored 11 students and managed 6 technical employees in research projects while monitoring for top performance. • Served as a vital member of the multicenter international research group participating in various collaborations with defense forces and contractors on essential translational research projects.

• Functioned as a core member of the international research group aiming to identify crucial signaling in epileptogenesis.• Built and introduced a detailed model for a long term in-vivo monitoring of epileptogenesis assuring the project was completed on time and exceeded expectations. • Complied with all applicable safety policies, practices and procedures within the lab. • Developed, improved and customized samples, equipment, processes and analytical methods.

Tel-Aviv, Il

• Planned and managed the information unit’s annual budget of $6M including preparing and producing an accurate budget report for up to 20 of the information unit’s businesses/customers.• Cultivated, managed and maintained strong working relationships with external vendors and internal stakeholders to drive continued business growth. • Utilized strong analytical and conflict resolution skills to identify, track, report and resolve critical issues in a timely manner.• Employed strong problem solving and creative/critical thinking skills to understand business needs and translate them into appropriate solutions.

Tel-Aviv, Il

• Oversaw all aspects of data cleansing within the information systems unit assuring 100% accuracy.• Assisted in characterizing unique, tailor-made information systems for diverse headquarter departments and business units to enhance organizational efforts. • Recommended changes in development, maintenance and system standards to senior management and key stakeholders.• Consistently exceeded expectations ensuring projects were on time, compliant to standards and met business needs.

Postdoctoral Research Fellow, Neuroscience And Genetic Medicine

Doctor Of Philosophy (Ph.D.), Neurophysiology

Master Of Medical Sciences (M.Med.Sc.), Neurophysiology

Bachelor Of Science (B.Sc.), Biophysics