Marc Hafner Email & Phone Number

As a group leader in Oncology Bioinformatics at Genentech, I am managing computational biologists who collaborate with experimentalists in Discovery Oncology to identify new therapeutic targets, develop novel drugs, and find biomarkers of sensitivity. My group and myself are bioinformatics leads for multiple molecule programs and I am also the biology lead for one of them. Beyond our contributions to advance drug pipeline projects, we are analyzing multimodal data to understand drug response. For my personal research, I am leveraging pre-clinical and clinical data including real-world data to study drug mechanisms of resistance in breast cancer. In the department of Oncology Bioinformatics, I am leading the implementation of a drug response software suite that includes the GR method and interactive visualization tools. I am also a member of the Roche-wide HR+ Breast Cancer Disease Area Community team that aims at identifying opportunities to advance treatment for Breast Cancer patients.Prior to Genentech, I completed my PhD at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland in 2011. I pursued my training as a Swiss National Science Foundation Fellow in Professor Sorger's laboratory at Harvard Medical School (HMS). During my postdoctoral research, I published a new method for normalizing drug response data to avoid artifacts and applied it to determine the impact of polypharmacology of CDK4/6 inhibitors on drug response.

Listed skills include Systems Biology, Bioinformatics, Molecular Biology, Matlab, and 40 others.