Haley Lynch Email & Phone Number

-Performed high throughput screening of therapeutic RNA targets via automation for drug candidate identification and validation-Designed and executed immune-based assays to determine if drugs of interest elicit an immune response-Developed and troubleshooted cell-based assays to determine drug parameters in an array of cell lines

-Spearheaded efforts to develop a novel peptide:ASO transport system for transport of si alpha-synuclein across the blood brain barrier in mouse models of and human patients with Dementia with Lewy Bodies-Managed multiple laboratory departments for efficient completion of experiments-Designed and implemented experimental protocols ranging from animal work to iPSCs

East Lansing, Michigan

-Led a collaborative investigation on the role of neuronal oxidative stress in Alzheimer’s disease -Elucidated the redox sensitivity of a key transcription factor involved in learning and memory ΔFosB using in vivo models of oxidative stress-Communicated findings through publication of 7 poster sessions and 3 articles in high-impact journals

-Researched the effects of immune response induced by early life adversity and found a role for transcription factor ΔFosB in connecting the gut-brain axis-Drove the lab’s participation in this joint lab project-Developed a better understanding of the high co-morbidity of depression and gastrointestinal tract dysfunction using models of early life stress and histological analysis of mast cells

Boston, Massachusetts, United States

-Discovered 3 potential therapeutic targets using genetic and pharmacogenomic analysis while uncovering the genetic overlap of Schizophrenia and Autism.-Learned about and participated in the research and development process in pharmaceutical industry through attendance at company meetings -Adapted to a virtual investigative format in a fast-paced environment

Holland, Mi

-Collaborated with 3 coworkers to classify a possible tumor suppressor protein using cell-based assays-Reported that mutations in the neddylation sites of the protein alters its growth-suppressive properties and angiogenesis-Communicated findings during 4 poster and oral presentations

Holland, Mi

-Analyzed the effects of excessive heat exposure on the kidneys of rats using ethical animal care-Improved time management of competing priorities of class and lab work

Doctor Of Philosophy (Ph.D.), Physiology, General

-Research Supervisor-Trained an undergraduate student in laboratory techniques including Western blotting, brain morphology, and tissue.

Bachelor Of Science (B.S.), Biology, General

Activities and Societies:-Phelp's Scholar Program-Fostered cross-cultural relationships with members within and outside of the program.