Hanhee Lee, Ph.D. Email & Phone Number

Toronto, On, Ca

Toronto, Ontario, Canada

•Write Phase I-IV and Bioequivalence Study Protocols and Informed Consent Forms.•Perform Literature search, NDA review and scientific discussion relevant to designing a study protocol for BE and Phase 1-2a (Proof of concept)•Review non-clinical data in preparation for the transition to the First in Human clinical trial.•Interact efficiently with PK Scientists and Biostatisticians to make sure that the study design is in line with the most updated regulatory and scientific requirements.•Interact with Institutional Review Boards with respect to Protocols, Informed Consent Forms and other documents as required.•Assist in the development of Standard Operating Procedures (SOPs) and guidelines linked with the department's activities.•Assist with the preparation for Regulatory agencies and participate if needed in any discussion with the inspectors. •Work closely with scientific, clinical personnel, and the Principal Investigator to ensure that clinical study protocol and other scientific documents are produced to the standard required by Good Clinical Practice (GCP), SOP and other applicable guidelines. •Establish optimal timelines with external departments to meet study timelines.•Perform other work within the Scientific Affairs department as needed.

Toronto, Ontario, Canada

In Dr. John Peever's Lab at the University of Toronto• Investigated how sleep disruptions affect brain activity using complex research tools including fiber photometry, calcium imaging and electrophysiology (EEG/EMG)• Expertise in processing biological signals.• Educated graduate students on research techniques and scientific back• Written scientific research paper (2 pending)

Ontario, Canada

In Dr. John Peever's Lab at the University of Toronto• Investigated the neural network underlying the pathophysiology of narcolepsy using optogenetics, Ca2+ imaging fiber photometry, electrophysiology, chemogenetics and neural circuit mapping in a preclinical model of narcolepsy (i.e., orexin-knockout animals)• Experienced evaluating spread and aggregation of misfolded protein in neurodegenerative diseases (i.e., RBD and Parkinsons disease) in animal model• Developed hypotheses and designed/executed/analyzed experiments in independent and grouped settings• Published scientific documents including journal, abstract, commentary, and textbook• Written scientific proposals for external funding and received a total of 35k$• Written standard operating protocols and animal use protocols for scientific experiments• Actively engaged in the scientific community by presenting 5 oral and 3 poster presentations at national and international conferences and received 3 awards based on scientific meritORAL PRESENTATIONSCanadian Sleep Society (CSS) conference (October 2021, virtual)Cell and Systems Biology Research Seminar, University of Toronto (January 2020, Toronto ON, Canada)Brain and Behavior Seminar, University of Toronto (January 2020, Toronto ON, Canada)World Sleep Congress 2019 (September 2019, Vancouver BC, Canada)Sleep 2019 (June 2019, San Antonio TX, United States)POSTER PRESENTATIONSWorld Sleep Congress (September 2019, Vancouver BC, Canada)Gordon Research Conference and Seminar: Sleep regulation and function (March 2018, Galvaston TX, United States) University of Toronto Cell and Systems Biology Research Day (May 2018, Toronto ON, Canada)

Ontario, Canada

CSB 445H1: Topic in Sleep Research (2020-2021)CSB 346H1: Respiratory Neurobiology (2017-2022)CSB 343H1: Animal Energetics (2020-2023) HMB496Y1: Research Project in Human Biology (2018-2019)CSB 345H1: Sleep biology (2017 -2019)

• Actively collaborated with opinion leaders, including principal investigators and clinical veterinarians, to oversee all aspects of animal ethics and care in research settings• Liaised between principal investigators and clinical veterinarians to reach mutual consent in relation to animal research• Reviewed and advised over 100 animal use protocols and standard operating protocols to promote top-quality research while ensuring compliance with federal, provincial, and institutional requirements

Bachelor Of Science - Bs, Cell/Cellular And Molecular Biology

Dean's List Scholar in the year of 2015

Phd, Neurobiology And Behavior, 4.0

The University of Toronto, Department of Cell and Systems Biology, Dr. John Peever's Lab. Research topics: Sleep biology, sleep disorder.