As a Professor of Practice and Director of the Center for Biostatistics and Health Data Science at Virginia Tech, I have 30 years of experience collaborating with clinical investigators on studies involving population health and EHR data, claims and resource use data, cancer, patient reported outcomes, aging and transitions, sleep, stress, obesity, and health disparities. Through my work in pharma, I have experience designing studies involving primary data collection to support early phase human subject clinical trials through large population-based post surveillance studies. In academia, I have extensive experience analyzing observational data, both prospective and retrospective, including large publically available datasets requiring complex sample survey methodology. I have been instrumental in the design and analysis of various studies involving oncology and the microbiome, treatment, symptoms and quality of life, survival, preferences, decision-making, and utilities. My work focuses on the application of contemporary and sophisticated methods to address research questions within a team science framework, including longitudinal data analysis (eg, hierarchical nonlinear mixed effects modeling), propensity score modeling, and machine learning methods. I am a fellow of the American Statistical Association. I have been a member of the PCORI review panel since its inception and a statistical reviewer for many high-impact peer-reviewed journals. As an independent collaborating biostatistician, my partnerships include national cooperative groups, along with clinical investigators from the University of Pennsylvania, Stanford, UDel, UMD, UH, Duke, Christiana Health Care System, and Weight Watchers. I have an impressive funding record and over 300 published peer-reviewed journal articles. I am an active member of many professional organizations, including Council of Chapters Representative, Board of Directors for the ASA.