Hannah Macpherson Email & Phone Number

London, Gb

London, England, United Kingdom

I am studying the transcriptomics of Parkinson's disease, supervised by Professor John Hardy and Professor Mina Ryten.

London

London, England, United Kingdom

I use a Pacific Biosciences Sequel IIe and Oxford Nanopore technology (PromethION and MinION) to run a number of projects for clients: from full genomes to targeted amplicons, CRISPR-based targeting, probe-based targeting methods and transcriptomics. I also generate quotations, manage the accounts, coordinate with the relevant companies, manage orders, train staff members, extract DNA and RNA from brain tissue and blood, and provide project planning advice for our clients.

Department of Infectious Diseases, Coronavirus Lighthouse Laboratory. Working in containment levels 2 and 3 across two locations. Performing RNA extraction using robotics and qPCR to assess positivity in both NHS and internal Imperial College samples.

London, United Kingdom

Long Read sequencing of both class I and class II HLA alleles at full length using Pacific Biosciences RSII platforms. Predominantly worked on definitively genotyping HLA-DQB1 and HLA-DRB1 in a cohort of 891 patient and donor pairs.Additionally: regular processing of blood samples, DNA extraction, culturing of B-LCL cell lines, genotyping for CCR5 mutation presence/absence and KIR presence/absence assays for the International KIR Exchange, run by UCLA.Publications:Liu, Y.L., Macpherson, H.L., Pryke, O.L., Marsh, S.G. and Mayor, N.P., 2019. Identification of a new allele, HLA-DRB1* 01: 01: 01: 02 discovered using third-generation sequencing. Hla, 94(5), p.458.Alanazi, H., Alqasem, A., Aloufi, F., Macpherson, H.L. and Hajeer, A.H., 2019. The novel HLA-DQB1* 06: 358 allele, identified by Next-Generation Sequencing in a Saudi individual. Hla.Thomas R. Turner, Daniel R. Hayward, Arthur W. Gymer, Dominic J. Barker, Gayle Leen, Charlotte A. Cambridge, Hannah L. Macpherson, Xenia Georgiou, Michael A. Cooper, Jonathan A. M. Lucas, Daud Nadeem,James Robinson,Neema P. Mayor and Steven G. E. Marsh. 2022. Widespread non-coding polymorphism in HLA class II genes of International HLA and Immunogenetics Workshop cell lines. HLAAbstractsThomas R. Turner , Daniel R. Hayward , Arthur W. Gymer , Dominic J. Barker , Gayle Leen , Charlotte A. Cambridge , Hannah L. Macpherson , Xenia Georgiou , Michael A. Cooper , James Robinson , Neema P. Mayor , Steven G. E. Marsh. 2020. HLA Class II Haplotype Diversity in International HLA and Immunogenetics Workshop Cell Lines. European Federation for Immunogenetics (EFI). Hla, 95(4), 272–422. Oral Presentations.European Federation for Immunogenetics (EFI) 2022 Poster Abstract. Discovering novel polymorphism in full-length HLA-F, -G and -DRA genes with SMRT DNA sequencing. Thomas R Turner, Jonathan AM Lucas, Matilda C Tierney, Hannah L Macpherson, James Robinson, Neema P Mayor, Steven GE Marsh

I completed a project entitled "Investigating Sex-Specific Differences and the Effects of Reduced Insulin-Like signalling on Protein Homeostasis in C.elegans" in the Gems Lab in the IHA. This involved work with polyQ aggregation in multiple tissues, genetic crosses to generate new strains, and thermotolerance assays. I presented my findings in the form of a poster presentation, as well as a written report.Grades: 81 (written report), 74 (presentation)

London, United Kingdom

I was Producer of "Rhapsody 2018" in The Shaw Theatre in the West End. The show comprises 24 iconic contemporary songs with new twists, and includes set-ups ranging from acappella to rock bands, and from choirs to string quartets. This involved coordinating 110 musicians, a Production team of around 20, organising Arrangers and Musical Directors, interviewing and hiring assistants, holding auditions and liaising with UCL Stage Crew Society, UCL Art Society and UCL Union. I also successfully pitched the show in a presentation alongside the Director and the 2017/18 President to the UCL Theatre Users Board.My role encompassed administration, budgeting, set design, marketing, sales, working with graphic designers, working on the creative aspects alongside the Director, organising photographers and videographers, and ensuring the smooth running of the show. We completely sold out both nights, at 430 tickets per night, made a good profit, and received a standing ovation on the final night.

London, United Kingdom

Ucl

I was elected President of a 250-member society, and after my year of leadership, we had expanded to over 300 paid members. I managed a committee of 19, lead our meetings, and we organised a large number of events, including regular Open Mic Nights, Workshops, Gigs, an annual Battle of the Bands competition, a Theatre Show and recorded live sessions in collaboration with UCL Film & TV Society. I acted as the main point of contact between the society and the Students' Union, and also arranged collaborations with other groups on campus. Under my leadership, the society won its first ever awards – “Most Developed Arts Society”, “Best Project”, “Best Bloomsbury” (large-scale show) and “Best Collaboration”, the latter for a Gala with 5 other societies, for which I was Producer for our section. We were also nominated for 'Arts Society of the Year'.

London, United Kingdom

I produced the Live Music segment of the UCL Comedy Gala 2017, in aid of Comic Relief. The section was 20 minutes long and involved a variety of different music, and multiple vocalists. I was on the audition panel, scheduled rehearsals, sourced props and costumes, helped with light plotting and worked with the sound engineer. The Gala went on to win 'Best Collaboration'.

London, United Kingdom

I was Assistant Producer of a Live Music Show in The Shaw Theatre. The production involved coordinating seventy musicians, arrangers, musical directors and a publicity team. The show also showcased ten recorded 'Bloomsbury Sessions', which were produced especially for the show. We made a large profit and almost sold out both nights. We won the 2016/17 UCL Union Awards for 'Best Bloomsbury' (large scale theatre show) and 'Best Project' for 'Rhapsody 2017' and 'The Bloomsbury Sessions' respectively.

Manchester, United Kingdom

I was selected to take part in an eight week lab placement for undergraduates, funded by the Wellcome Trust. I worked in Professor Phil Woodman’s lab, whose research focuses on cell trafficking and LITAF, mutations of which have been linked to Charcot-Marie-Tooth disease. My project was based on interactions between LITAF and various other cellular proteins, and gave me the opportunity to practice my lab techniques, including cell culture. I was able to better understand how labs are run, and what it is like to work in one.

Ucl

I was elected Secretary of a 250-member society after being involved in society events in 2014/15. My responsibilities included sending weekly newsletters to 2,000 recipients, replying to queries via email, organising meetings with the committee, taking minutes, involvement in hosting auditions and taking part in the planning of events hosted by the society. I served on a team of 15 committee members.

Ucl

I was responsible for the production of a series of live recorded sessions in collaboration with UCL Film & TV Society. These were released online as the 'YouTube Sessions', and were also screened to 500 people in our annual theatre show. My role involved liaising with and selecting acts, booking locations, organising equipment and managing and leading a team of five, which included sound engineers and videographers.

Colchester, England, United Kingdom

Colchester, England, United Kingdom

Biological Sciences Msci, Cell Biology, 1St

Activities and Societies: UCL Biology Society, UCL Live Music SocietyFirst year modules: Cells and Development, Fundamentals of Biology.

Gce A Levels, Biology, Chemistry, Mathematics, Geography, Critical Thinking, General Studies, 2X A*, 4X A