Hannah Wiedner, Phd Email & Phone Number

Chapel Hill, Nc, Us

Durham, Nc

Chapel Hill, Nc

• Investigated the role of RNA binding proteins and epigenetic modifications in regulating splicing transitions during skeletal muscle and heart development• Analyzed high-throughput transcriptomic datasets using bioinformatic tools to determine differential gene expression, splicing, and distribution of chromatin marks• Defined the function of splice-isoforms in muscle development using cell culture models, biochemical assays, microscopy, proteomic analysis, and… Show more • Investigated the role of RNA binding proteins and epigenetic modifications in regulating splicing transitions during skeletal muscle and heart development• Analyzed high-throughput transcriptomic datasets using bioinformatic tools to determine differential gene expression, splicing, and distribution of chromatin marks• Defined the function of splice-isoforms in muscle development using cell culture models, biochemical assays, microscopy, proteomic analysis, and RNA-sequencing• Co-founded an outreach program serving over 350 students and raised over $5,000 in grant funding Show less

Chapel Hill, Nc

• Created a new outreach program that organizes scientific shadowing trips for middle and high school students• Brought memorable science experiences to over 350 students via 9 visits spanning 250 miles across North Carolina• Built a network of 150 science ambassadors• Secured $5,000 in funding as part of a partnership with ROSETTA Commons

• Developed an assay for the optimization of transgene expression to enhance therapeutic efficacy of adeno-associated viral vectors• Created standard operating protocol for efficient screening of vector sequences• Presented findings and deliverables at company meeting

• Characterized bromodomain and chromodomain control of drug seeking behaviors• Used BET inhibitors to modulate target gene expression in fear conditioning• Screened nociceptin receptor agonist for treatment of cocaine addiction

• Rehabilitated injured manatee calves and adolescent howler monkeys • Assisted in the socialization and treatment of white-faced Capuchin adults • Educated locals about safe boating procedures and the dangers of the pet trade in Belize

• Developed a pipeline for RNA-Seq data analysis and pathway visualization in Cytoscape

• Taught 15 middle school students computer programming skills following eIMACS, University Computer Science I, and Turtle logo curriculum.

• Examined the interaction of ERK and EpCAM in MCF7 and T47D cells as a mechanism of Tamoxifen resistance

Bachelor Of Science (B.S.), Neuroscience And Biochemistry & Molecular Biology

Doctor Of Philosophy - Phd