Harrison P. Rahn, Ph.D. Email & Phone Number

Palo Alto, Ca, Us

Palo Alto, Ca, Us

Palo Alto, California

As a member of the Wender Lab, I my focused is on the development of novel drug delivery platforms with direct application in emergent therapies. One focus of our subgroup is the development of antibiotics for treatment of antibiotic-resistant bacterial pathogens. Through this research we developed generalizable strategies to synthesize drug-transporter conjugates such as novel macrolide conjugates with expanded spectrums of activity and significantly improved potency. This work is carried out alongside development of gene delivery platforms which facilitate in vivo gene transfection, enhanced ex vivo transfection, and delivery of novel therapeutics. Both of these efforts sought to reach clinical applications while simultaneously furthering scientific endeavors in the broader fields of medicinal chemistry. Cumulatively, syntheses were designed to maximize scalability and translation to industrial settings by minimizing the use of column chromatography in favor of crystallization, precipitation, and dialysis.

Greater New Orleans Area

I designed and conducted experiments on the ACOMP and ARGEN platforms to collect meaningful data for marketing applications and hypothesis driven application notes. Using ACOMP, an autonomous live polymer reaction monitoring system, I performed reaction monitoring, analysis, and optimization of acrylates and polyurethanes in conjunction with fluidics engineering to optimize the product for consumer use. Using the ARGEN, an autonomous multi-sample Dynamic Light Scattering (DLS), platform I studied protein aggregation kinetics to aid in stable formulation development

Tulane University

I conducted research of rodent vectored disease and urban ecology under Dr. Michael J. Blum from May 2014-August 2014. During this time I developed skills related to community involvement, rodent handling, and necropsy of potentially harmful biological samples. From September 2014- June 2017 I researched organic synthesis of light harvesting complexes for biological sensing. The later work contributed to an Honors thesis and Masters thesis detailing light generating molecules and a novel methods of cellular imaging. During this research I designed, synthesized, and detailed a structure-function relationship with a new class of firefly luciferin analogues designed to report supramolecular Host-Guest complexation in vitro.

Doctor Of Philosophy - Phd, Organic Chemistry

Publications: Vancomycin-Dendrimer Conjugates - https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.3c00168 Vancomycin-Biguanide Conjugates.

Master Of Science - Ms, Chemistry, 4.00

In my fourth year at Tulane, I completed the requirements for a Master of Science in Chemistry. This included graduate course work among.

Bachelor'S Degree, Ecology & Evolutionary Biology; Chemistry, 3.73

Activities and Societies: Tulane University Marching Band, Tulane Karate Club (Captian, Treasurer, Vice-President, President), Soundwave.

High School, Weighted 4.67 Unweighted 3.90; Class Rank: 6Th Of 305

Activities and Societies: Glenelg Marching and Concert Band, Varsity Wrestling, AP Scholars