Harshit Kumar Soni, Ph.D. Email and Phone Number

Teaching and Research in the fields of Bioinformatics, Developmental Biology, Cell & Molecular Biology, and Biochemistry. Provide internship, and project guidance to UG and PG students.

Teaching and Research in the fields of Bioinformatics, Developmental Biology, Cell & Molecular Biology, and Biochemistry. Provide internship, and project guidance to UG and PG students.

Incharge of Swami Vivekananda Career Guidance Scheme. Provide Career Guidance, Assistance In Career Planning, Competitive Exam Preparation, Personality Development.

Create Search and AI resistant domain specific questions to train and development of LLM.Present Assignment: Project LION (OPEN AI)

Primary cancer tissue processing and culture. Evaluation of primary cancer tissue culture for long term culture, drug efficacy, and therapy decision. Primary tissue and PBNC co-culture, flow-cytometry. Report preparation, project management,

NGS Analysis, RNAseq, ChIPseq analysis, Linux, Python, and R programming.

Provide Application support for BioTek's product line included augmented cell imaging solutions,, PLA, UV-vis, luminescent, and fluorescent readers. Responsible for training seminars, Product presentations, scientific presentations and conference presentation. collaborative initiatives with sales, R&D and customer support regarding protocol and assay development and performance testing. Responsible for the organizing workshop and product demo.

Application support to sales and marketing team. Pre and post sale support. Help scientists to design/optimize experiment related to particular instrument, skill update of scientists. Help them choosing right product (consumables and instruments) for specific technique/application. Work collaborative with marketing and sales team. Making personal and central presentation about products at customer sites. Prepare marketing materials –PowerPoint presentations, product brouchure, introductory… Show more Application support to sales and marketing team. Pre and post sale support. Help scientists to design/optimize experiment related to particular instrument, skill update of scientists. Help them choosing right product (consumables and instruments) for specific technique/application. Work collaborative with marketing and sales team. Making personal and central presentation about products at customer sites. Prepare marketing materials –PowerPoint presentations, product brouchure, introductory mails and scientific notes etc. Following portfolios are being handled;Merck Cell Biology -Amnis, Guava, Muse, Luminex, etc.Perkin Elmer -IVIS invivo imaging systemsQuanterix : SIMOASolentim: VIPS™ (acronym for "Verified In-situ Plate Seeding") single cell seeding system and Cell Metric (https://www.solentim.com/products/)MILabs: Preclinical imaging solutions (PET/SPECT/CT/OI) Show less

Most of the work was done at Piramal Lifesciences Ltd. Mumbai with Dr. Nishigandha Naik who was then Head, Imaging and Cancer Biology Department at Piramal Lifesciences Ltd.Formyl peptide receptor (FPR) are chemoattractant receptors, which belong to the G protein coupled receptor (GPCR) family. These receptors are mainly present on professional phagocytes activated by n-formyl peptides released from bacteria and mitochondria, leading to the trafficking of phagocytes towards sites of… Show more Most of the work was done at Piramal Lifesciences Ltd. Mumbai with Dr. Nishigandha Naik who was then Head, Imaging and Cancer Biology Department at Piramal Lifesciences Ltd.Formyl peptide receptor (FPR) are chemoattractant receptors, which belong to the G protein coupled receptor (GPCR) family. These receptors are mainly present on professional phagocytes activated by n-formyl peptides released from bacteria and mitochondria, leading to the trafficking of phagocytes towards sites of bacterial invasion and tissue damage. Other than phagocytic leukocytes, FPRs have been also detected in mesenchymal stem cells (MSCs), dendritic cells, astrocytes and hepatocytes, etc. Furthermore, stage dependent increase in FPR expression has been seen in glioma. Their biological significance in these cells and tumors is not well understood. Earlier from our lab, it has been reported that functions stimulated by FPRs were found to be defective in PMNL (Polymorphonuclear Leukocytes) of chronic myeloid leukemia (CML) patients. Over the past few years, data from several groups have indicated that these receptors might act in a more complex manner. Hence, the studies were aimed to decipher role of formyl peptide receptor in transformed cells and thereby to understand their function in non-hematopoietic and cancerous cells. Work has been carried out using breast cancer cell lines as a model system for solid tumors and bcr-abl positive cell lines as well as mononuclear leukocytes and polymorphonuclear leukocytes (PMNL) fractions from peripheral blood samples of CML patients as model system for CML. Show less

Worked at Cancer Biology and Imaging division of Pharmacology Department. Involved in Model Development, NCE development and in vitro & in vivo preclinical studies. Projects Undertake: 1) Establishment of Cancer and Imaging lab and facility2) Preclinical studies and drug discovery for various projects.3) Development of novel drug delivery system for Glioblastoma.4) Development and evaluation of gene therapy modalities for Chronic Myeloid Leukemia.

Worked as a Project Assistant on DST sponsored project “Design, Synthesis and Biomedical applications of Oligonucleotides in Nucleic Acid-Molecular Recognition Processes”

Subjects: Molecular Biology, Cell Biology, Tissue culture and Biochemistry to Under Graduate and Post Graduate students.

Study Of Prevalence Of Parasitic Carriers In Healthy Individuals Of Mumbai And Development Of Molecular Biological Techniques For Diagnosis Of Microorganism And Parasites” under the guidance of Dr. B.R.Das, Director R&D.

Worked on M.Sc. dissertation project “To evaluate the Effect of bcr-abl on the expression of actin and formyl peptide receptor (FPR) gene in Polymorphonuclear Leukocyte (PMNL) of Chronic Myeloid Leukemia (CML) patient by RT-PCR”. at Biochemistry and Cell Biology dept. of Advance Center for Treatment, Research and Education in Cancer (ACTREC), Navi Mumbai under the guidance of Dr. Nishigandha Naik.

Attended summer Training on various techniques in Animal Biotechnology