Harvey Homan

Harvey Homan Email and Phone Number

Targeting EMT to stop metastatic cancer. @ Keiretsu Forum Mid-Atlantic
Harvey Homan's Location
Pittsburgh, Pennsylvania, United States, United States
About Harvey Homan

Dr. Homan returned to the rigorous demands of leading a start-up therapeutics company and co-founded MetasTx, LLC with Drs. Somanath Shenoy and Brian Cummings because he was so impressed with the published results from their academic research and strongly believes they have identified a potential breakthrough drug that may significantly improve the armamentarium for treating metastatic cancer to greatly extend and improve patients' lives. Since formation in August 2021, MetasTx has made great progress and is poised to begin IND-enabling studies that will lead to the critical First-In-Human clinical studies. Dr. Homan has drawn upon his academic background in pharmacology, as well as hands-on and senior leadership experience in a broad range of patient focused therapeutic categories in start-up and multi-billion dollar healthcare companies to build an extensive global network that he can call upon as needs arise. As Founder and CEO of biotech and medical device companies in USA and UK he has achieved successful marketing authorization, commercialization and exits, and has had extensive experience transitioning technology from academic labs to businesses, including recent projects in neurodegenerative and psychiatric diseases. For Sterling Health and The Boots Company (BHI), he led growth of businesses in consumer-focused pharmaceuticals and has led commercialization of hundreds of successful products. At Sterling, he rapidly progressed through clinical science, marketing and sales to lead R&D, regulatory and clinical affairs for Europe, led global Analgesic, GI, and Skin Care portfolios and instituted innovative product development organizations and processes. Dr. Homan led all scientific, medical, regulatory and development functions for start-up BHI with teams in the UK, France, Germany, Australia, and Thailand. He was responsible for integration of all scientific, medical and regulatory functions for two major acquisitions, and development of partnerships in Europe, U.S., India and Japan that built BHI to £500 million revenue and resulted in a £2 billion sale to Reckitt Benckiser in 2005. As Head of Corporate Development and Innovation for Boots plc, he led institution of best practices internationally, and coached Directors in value creation through innovation. He has served as a Director for Whitehorse Recovery Center, NH, and is a member of the Steering Committee for CUMC TRx Accelerator, as well as a successful angel inveator. Dr. Homan has a PhD in Pharmacology from UGA and a MBA from NYU Stern.

Harvey Homan's Current Company Details
Keiretsu Forum Mid-Atlantic

Keiretsu Forum Mid-Atlantic

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Targeting EMT to stop metastatic cancer.
Harvey Homan Work Experience Details
  • Metastx-Llc
    Chief Executive Officer And Co-Founder
    Metastx-Llc Aug 2021 - Present
    Metastatic cancer (mCa), led to 10 million global deaths (2021), despite a $72B drug market (projected to grow to $138B by 2032). MetasTx initial therapeutic target is metastatic prostate cancer (mPCa). 3.2M US men, were living with PCa in 2020; more than 227K had mPCa, with median expected survival of 4.2 years. There is a significant unmet need for drugs to treat or prevent mPCa without depleting testosterone, destroys quality of life. MetasTx intends to stop epithelial-mesenchymal transition (EMT), a crucial process for cancer metastasis, by blocking PAK1 activation. Decades of research by Dr. Somanath Shenoy (co-Founder, CSO) have focused on molecular and genetic mechanisms of cell functions critical to mCa and revealed high expression of PAK1 in prostate and breast cancers. A small molecule (IPA3) blocks PAK1 in vitro but is not effective in vivo. Collaborating with Dr. Brian Cummings (co-Founder, Advisor), Shenoy demonstrated that a plasma-stable patented formulation of IPA3 inhibited growth of PCa xenografts, metastasis to lung and bones, as well as the destructive actions of PCa cells injected into bone. MetasTx currently is synthesizing compounds from a library designed by David Crich, PhD, Head of Chemistry (GRA and David Chu Eminent Scholar In Drug Design) and screening these compounds in studies led by Dr. Jackson (Jay) Gibbs, PhD, Head of Biology (formerly Sr. Director of Ca Research, Merck & Astra Zeneca), to identify an optimized lead that will be scaled up for IND enabling studies, leading to IND approval and First in Human (Phase 1 / 2) clinicals projected for completion by mid-2028. MetasTx will focus on discovery, development, and early-stage clinicals, partner for later clinicals, commercialize through licenses and exit through acquisition. A highly entrepreneurial team of experienced, advisors support our vision to change the course of this terrible disease to improve the length and Quality of Life for patients with metastatic cancer.
  • Keiretsu Forum Mid-Atlantic
    Member
    Keiretsu Forum Mid-Atlantic Mar 2020 - Present
    Philadelphia, Pennsylvania, Us
  • Keiretsu Forum Mid-Atlantic
    President, North Jersey Chapter
    Keiretsu Forum Mid-Atlantic Oct 2020 - Mar 2023
    Philadelphia, Pennsylvania, Us
    Keiretsu Forum is a global investment community of accredited private equity angel investors, venture capitalists and corporate/institutional investors. Keiretsu Forum was founded in the San Francisco East Bay in California in 2000 by Randy Williams. Keiretsu Forum is a worldwide network of capital, resources and deal flow with 53 chapters on 4 continents with more than 2500 accredited investor members. Keiretsu Forum members invest in high-quality, diverse investment opportunities. Keiretsu Forum North Jersey will join NYC, Philadelphia, Pittsburgh and Metro DC as the 5th chapter in Keiretsu Forum Mid-Atlantic.
  • Hdh Associates International Llc
    Principal
    Hdh Associates International Llc May 2015 - Present
    HDH Associates International LLC supports early stage life sciences companies as they tackle milestones critical to success. The advantage that HDH Associates International LLC offer to your Life Sciences clients is “hands-on” personal success with a number of areas that will be critical to their growth and success and a well developed network of experts in the US, Europe and select Asian countries.
  • Columbia University, Irving Institute For Clinical And Translational Research
    Steering Committee Member - Columbia Trx
    Columbia University, Irving Institute For Clinical And Translational Research Jan 2018 - Present
    The Translational Therapeutics (TRx) Resource is an accelerator program designed to leverage Columbia’s proficiency in drug discovery and provide access to Entrepreneurs and the pharmaceutical industry to advance novel therapeutics from the lab towards the path of commercialization and clinical implementation.
  • Sagemedic Corporation
    Senior Vice President Business Development
    Sagemedic Corporation Nov 2020 - May 2021
  • Sagemedic Corporation
    Senior Advisor To Ceo
    Sagemedic Corporation Jun 2020 - Oct 2020
    SageMedic’s proprietary 3D SAGE Direct Platform is an ex-vivo, high throughput assay that predicts individual responses to various anti-cancer therapies, including chemotherapies, targeted therapies, and possibly immunotherapies. The SAGE Direct Test™ is designed to accurately predict the most effectivecancer treatment within just 1 week.
  • White Horse Addiction Center Inc
    Board Member
    White Horse Addiction Center Inc Apr 2020 - Oct 2020
  • Jumpstart Nj Angel Network
    Member
    Jumpstart Nj Angel Network Sep 2017 - Jun 2020
    Jumpstart is a private member-lead angel group that invests in early-stage technology companies in the Mid-Atlantic region
  • Columbia Biomedical Technology Accelerator
    Member Of The Board Of Advisors
    Columbia Biomedical Technology Accelerator Feb 2018 - Jun 2019
    The Columbia Biomedical Technology Accelerator (formerly the Columbia-Coulter Translational Research Partnership) aims to catalyze the advancement of biomedical technologies by providing funding, education, resources and mentorship to teams of clinicians, engineers and scientists working to develop solutions to clinical unmet needs, with the ultimate goal of bringing innovative research out of the lab to benefit society.Project support is expected to serve as a bridge to commercial investment, with awards granted to perform specific tasks needed to validate a commercial hypothesis (vs. a scientific hypothesis).
  • Institute For Life Science Entrepreneurship (Ilse)
    Executive Director, Corporate Development
    Institute For Life Science Entrepreneurship (Ilse) May 2016 - Dec 2017
    Union, New Jersey, Us
  • Ingenion Medical Ltd
    Ceo / Director
    Ingenion Medical Ltd Sep 2013 - Aug 2015
    Ingenion Medical Limited, a privately-held, UK developer, manufacturer and marketer of innovative, life-enhancing medical technologies in the urology product field raised £1 million through Founders’ and Series A rounds. Under Dr. Homan, Ingenion acquired intellectual property; established partnership with ISO 13485 certified Malaysian manufacturer; obtained European marketing authorization (CE Mark) and initiated commercialization of innovative urinary drainage device in Germany and UK. Dr. Homan supported transition to CEO designate following Board decision that senior management needed to be based in Europe.
  • Urovalve, Inc.
    President & Ceo
    Urovalve, Inc. Feb 2004 - Dec 2012
    Led transformation of Urovalve from family run LLC to C-Corp. Successfully raised more than $4 million from private investors and $2.5 million as PI on grants from NIH and NJCST, and led development of an innovative intraurethral catheter from concept through successful US clinical trials.
  • Redpoint Bio (Linguagen Corp)
    President & Ceo
    Redpoint Bio (Linguagen Corp) 2001 - 2004
    Led transformation of company that applied biotechnology and advanced pharmaceutical techniques to provide superior flavor modifiers and sweeteners for pharmaceuticals, foods, and beverages from a contract/fee-for-service business model to a much higher value product commercialization model and strategically positioned the Company as the leader in developing innovative products for modification of taste perception. Renegotiated strategic partnership with major flavor and fragrance company that recognized Company’s ownership of products resulting from collaborative research efforts; negotiated rights to patent portfolio from Mount Sinai Medical School that provided technology platform. Initiated discussions; and conducted negotiations that led to development agreements with major pharmaceutical companies. Led program that achieved GRAS status for Redpoint Bio’s lead compound, thus avoiding the need for a long and expensive toxicology program, and won a $750 K Phase II SBIR grant. Linguagen achieved a successful private round of financing that laid the foundations for successful reverse merger to form Redpoint Bio.
  • The Boots Company Plc
    Sr. Vp Corporate Development/Innovation
    The Boots Company Plc 1999 - 2000
    Nottingham, Gb
    Reporting to the Deputy CEO with responsibility to accelerate innovation in all 5 business units, and identify significant new business opportunities. Frequent interactions with Chairman and Executive Board members. Identified key leadership and behavioral issues, facilitated coaching of senior executives, including members of the Board. Led introduction of processes to accelerate innovation in business units and to facilitate learning and knowledge-sharing. Won approval for major expansion into phytopharmaceuticals and negotiated exclusive sourcing contracts from Government Pharmaceutical Organization of Thailand.
  • Boots Healthcare International
    Vice President, Product Development & Scientific Affairs
    Boots Healthcare International 1994 - 1999
    Gb
    Responsible for global new product portfolio, internal product development, scientific/medical and technical functions, technology licensing and product acquisitions. Responsible for integration of development portfolio, people and processes following acquisitions of Hermal in Germany and Laboratoires Lutsia in France. Line responsibility in UK, France and Germany. Operating responsibilities in Thailand and Australia. Negotiated acquisition of products and technologies from McNeil, Prographarm, Banner and BASF; supply agreement with Shasun Chemicals and Drugs Ltd., India. Managed development program for flurbiprofen patch with Lead Chemical Company Ltd., Japan. Managed NDA program for tacalcitol for scalp psoriasis with Teijin Ltd., Japan. Leadership position in partnership between BHI and Piramal Ltd, India. Led Rx to OTC switch of ibuprofen and approval of OTC NDA for flurbiprofen based lozenge product in Europe.
  • Sterling Health Europe
    Vice President Research & Development
    Sterling Health Europe 1993 - 1994
    Selected by President of Sterling Health Europe to establish and lead R&D, regulatory and clinical affairs (40 people, $6 million operating budget) for newly formed regional organization. Coordinated management of global portfolio with VP Americas and VP Australasia. Global responsibility for cough/cold and gastrointestinal NPD strategy and portfolio.
  • Sterling Winthrop Inc
    Director Global Research & Development, Sterling Health Division
    Sterling Winthrop Inc 1991 - 1993
    Doha, Qa
    Led NDA program for S-Isomer of ibuprofen.
  • Sterling Winthrop Inc
    Director Of Marketing, Global Strategic Resources, Sterling Health Division
    Sterling Winthrop Inc 1989 - 1991
    Doha, Qa
    Led analysis, development and launch of the initial global branding strategy for gastrointestinal and respiratory illness businesses. Accelerated revenue growth (+30%) and significantly improved profit margins through reduction of inefficiencies.
  • Sterling Winthrop Inc
    Various Positions, Marketing And Scientific Affairs
    Sterling Winthrop Inc 1981 - 1986
    Doha, Qa

Harvey Homan Education Details

  • Nyu Stern School Of Business
    Nyu Stern School Of Business
    General
  • The University Of Georgia - College Of Pharmacy
    The University Of Georgia - College Of Pharmacy
    Neuropharmacology

Frequently Asked Questions about Harvey Homan

What company does Harvey Homan work for?

Harvey Homan works for Keiretsu Forum Mid-Atlantic

What is Harvey Homan's role at the current company?

Harvey Homan's current role is Targeting EMT to stop metastatic cancer..

What schools did Harvey Homan attend?

Harvey Homan attended Nyu Stern School Of Business, The University Of Georgia - College Of Pharmacy.

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