Hazel Housden Email & Phone Number

Oxfordshire, England, United Kingdom

Supporting the Rosalind Franklin Institute and our researchers to generate value and impact from our exciting technologies.

Abingdon, Oxfordshire

Abingdon, Oxfordshire

Abingdon, Oxfordshire

Analysis of sugars and solvents to support development of our industrial fermentation processes for production of bio-butanol and bio-acetone.

York, Uk

My most recent PDRA project was "Biotransforming Phenylpropanoids derived from Biorefining: a Toolkit Approach". In this I used a synthetic biology approach to convert low value by-products from biofuel production (phenylpropanoids from the non-fermentable woody residue) into high value compounds such as flavonoids which have important markets as flavour enhancers and antioxidants. This involved reconstructing plant metabolic pathways in baker’s yeast, using a combination of plant genes and enzyme activities that are native to the yeast. Another key part was characterising enzyme activities at different steps of the pathway in order to select combinations that enable efficient production of target molecules, and using a toolkit approach that allows the different biotransformation modules to be easily switched according to the feedstock and exact compound wanted. I enjoyed doing all parts of this project from molecular biology and fermentation through to enzyme purification and analytical biochemistry.Earlier PDRA projects involved studying proteins within protic ionic liquids (with spin-out Bioniqs), and developing biosensors with Dstl.

Southampton, United Kingdom

Producing and studying the properties of immunoglobulin-binding proteins.

Centre De Recherche Charles Zviak, Clichy, France

A 12 month biochemistry work placement in L'Oréal's body hygiene laboratory, investigating the molecular basis of underarm odour production.

Bsc(Hons)1St, Biochemistry With A Year In Industry

Phd, Biochemistry

The kinetics of ITAM phosphorylation in T cell activation