Expert in taking bioprocesses from bench to commercial scale. Techno-economic analysis, fermentation process development, scale-up/tech transfer, facility evaluation & process fit, piloting, and production scale process and equipment design.

Engineering the process for the economic production of sustainable meat.

Providing consulting services in fermentation and upstream development to deliver reliable and cost effective processes at scale. Guiding clients in bench-scale preparation for scale-up and to manage pilot campaigns to confirm performance metrics, generate data for large-scale process design and manufacturing, and produce material to garner interest from customers.

Microbial fermentation expert and accredited member of Lee Enterprises Consulting, a team of bio-economy consulting experts. Providing clients expertise in fermentation process development and data analysis, tech transfer, scale-up, upstream operation and process design, and techno-economic analysis.

Fermentation operations, process optimization, and developing processes for scale-up to pilot and manufacturing facilities. Managing pilot and manufacturing campaigns to deliver product in-spec and on time.

Engineering lead to develop and scale-up yeast fermentation processes for production of diacids and carotenoids, manage tech transfer and toll manufacturing to produce in-spec material of such products, develop economic models for production and purification, and serve as lead process engineer for upstream design and construction of fermentation facility.

Managed pilot/demo plant activities at contract facilities, prepared tech transfer packages for tolling operations, summarized demo plant findings in R&D report, collaborated with engineering team to design production facility, and established equivalency of fermentation process across scales. - Successfully transferred processes to scales of 3000L, 13,000L, 20,000L, and over 500,000L fermenters - Identified and characterized fermentation process sensitivities by coordinating research and scale-up activities between bench scale and demo plant - Prepared tech transfer package for successful campaign at tolling facility which produced 5 million pounds of a renewable chemical, 1,4-butanediol - Used data, modeling (Excel, MATLAB®, SuperPro Designer®), and engineering principles in collaboration with engineering design team to design fermentors and process for commercial BDO production facility

Led fermentation team to develop, characterize, and optimize fermentation process for production of renewable chemical, and coordinated fermentation operations and staff to execute over 30 fermentations/week. - Improved fermentation process, media, and screened strains through use of design of experiment approaches (JMP®, Design Expert®) to design and analyze process development studies - Collaborated with engineering team to define data driven technical criteria for design and operation of commercial fermentation process

Demonstrated capabilities of high throughput automated cell culture platform for process development and communicated effectiveness of platform internally and externally. Led controlled cell culture studies in bench and sub-milliliter bioreactors. Served as interim Product Manager and technical representative on Sales, Marketing, and Commercialization team. - Established process in micro-bioreactors to achieve equivalency to bench scale bioreactors for batch and fed-batch cell culture processes (CHO, NS0), proving effectiveness of company’s technology - Developed and demonstrated high throughput experimentation strategies using automated micro-bioreactor system to optimize cell culture processes and cut process development time by ½ or more

Led teams on contract driven evaluation of high throughput automated cell culture technology and to perform process optimization and micro-bioreactor platform evaluation research for pharmaceutical and biotech partners. - Managed evaluation contracts of up to $200,000, directed teams in evaluations that led to first 3 sales of multi-million dollar platform, and directed PD team that successfully completed fed-batch microbial process optimization contract worth $500,000 - Used DOE to characterize and optimize customer’s processes for production of cell based products

Performed early stage research and design of high throughput micro-bioreactor system capable of growth and control of prokaryotic and eukaryotic cells for production of biochemicals and screening of drug candidates. - Designed first generation micro-reactor by modeling flow and diffusion in micro-fluidic systems, use of soft lithography for rapid prototyping, and identified sensing strategy - Identified optimal geometry through mass transfer and momentum transfer modeling to ensure effective gas transfer and mixing, and then confirmed optimal design with experimentation