Hearne, Kenneth Email & Phone Number

California, United States

Los Gatos, California, United States

With extensive experience at Aridis Pharmaceuticals, I've merged lab management with impactful research. As a Lab Manager and Senior Research Associate, I've led operations, trained teams, and contributed to pioneering pre-clinical studies, fostering a safe and collaborative environment.🔬 Lab Oversight:• Orchestrated daily lab operations, optimizing progress and efficiency.• Trained teams on equipment usage, ensuring safety and precision.• Established strong vendor relationships for equipment maintenance.📅 Scheduling and Supplies:• Managed personnel schedules, ensuring smooth coverage.• Oversaw supply inventory and procurement, preventing disruptions.🧪 Technical Excellence:• Designed complex experiment plans, showcasing meticulous detail.• Executed innovative animal models, advancing drug administration methods.💡 Assay Innovation:• Led assay development and optimization, enhancing data accuracy.• Employed advanced techniques like Atomic Spectrometer analysis.📊 Data Management:• Maintained rigorous records, upholding research integrity.• Presented findings effectively, promoting collaboration.

As an Independent Contractor at KenHearne & Associates during June 2015 to July 2015, I provided my expertise as a consultant, specializing in model construction. In this short but focused engagement, I contributed to the following areas:🏗️ Collaborated with KenHearne & Associates to construct and develop sophisticated models.🔧 Utilized advanced techniques to design and implement intricate model structures.📊 Collected and processed relevant data, ensuring accuracy for model calibration and validation.🔍 Conducted rigorous testing and refinement of models, enhancing their predictive capabilities.📈 Assisted the team in presenting model outcomes and insights to clients for informed decision-making.

During my tenure at ISIS Service in San Carlos, CA, from March 2010 to July 2015, I held the position of Senior Research Technician. This role allowed me to actively engage in hands-on experimentation, precise data collection, and the responsible care of animals throughout various research endeavors. My specialized knowledge encompassing pharmacokinetics, toxicology, anesthesia administration, and surgical procedures significantly contributed to the accomplishments of diverse research projects undertaken by the Contract Research Organization (CRO).🐾 Spearheaded animal well-being: I ensured the ethical treatment and comfort of laboratory animals, maintaining their health and safety throughout the research process.💼 Expertly conducted experiments: My proficiency in designing and executing experiments was pivotal in obtaining accurate and reliable data for analysis and publication.🧪 Pharmacokinetic insights: Leveraging my expertise, I played a key role in investigating drug absorption, distribution, metabolism, and excretion patterns.🌡️ Anesthesia administration: My skillful administration of anesthesia enhanced the precision of surgical procedures, contributing to the success of various studies.🔬 Collaborative surgical expertise: I collaborated with interdisciplinary teams to perform surgical procedures, showcasing my adeptness in fostering a cooperative and efficient research environment.

Newark, California, United States

At Ardelyx, Inc. in Newark, CA, from April to June 2010, I held the position of Research Associate II/Pharmacology. Within this role, I actively participated in PD, PK, and efficacy studies involving rodents, encompassing tasks like dosing, blood collection, data entry, and animal care.🐭 Study setup and execution: I played a pivotal role in setting up and executing PD, PK, and efficacy studies, ensuring adherence to established protocols and standards.🩸 Blood collection expertise: Proficiently performed both catheterized blood collection and remote observation (RO) methods, collecting essential samples for analysis.📊 Data accuracy and entry: I meticulously recorded data and ensured its accurate entry, contributing to the integrity of the study results and subsequent analyses.🥼 Animal husbandry: Demonstrated a commitment to the welfare of research animals by providing attentive husbandry, maintaining their health and ensuring their comfort.📋 Methodical labeling and organization: Precisely labeled tubes and samples, maintaining meticulous organization to prevent errors and enable streamlined data interpretation.

At Unity Pharmaceuticals in Menlo Park, CA, spanning from May 2006 to July 2009, I held the role of Senior Research Associate/Laboratory Manager in the Pharmacology/Oncology Research division. My tenure was marked by hands-on involvement in a diverse range of tasks and projects:🧪 Cell-Based Assay Development: Utilized a robotic liquid handler system to create and optimize cell-based assays for high-throughput screening. Conducted cell proliferation experiments, determining cell viability for effective drug evaluation.🧬 Molecular Expertise: Performed RT-PCR for gene amplification, contributing to the comprehensive understanding of RNA. Executed western blots and ELISAs to assess protein expression levels.🧬 Assay Validation: Demonstrated proficiency in troubleshooting and validating assays for high-throughput screening of MAP Kinase Inhibitor libraries, essential for therapeutic advancements.🧫 Cell Line Management: Exhibited expertise in transfection, selection, and maintenance of mammalian cell lines, including the identification and expansion of stable clones.🐁 In Vivo Studies: Acted as a co-investigator, collaborating on in-vivo studies, protocol development, and execution. Developed specialized models such as the intra-nasal inflammation and Xenograft tumor models.📊 Data Analysis and Presentation: Analyzed data, generated comprehensive reports, and presented findings, contributing to the collective understanding of research outcomes.📝 SOP and Documentation: Authored SOPs, maintained detailed lab notebooks, and documented standard operating procedures (SOPs), ensuring methodical and organized research practices.📈 Collaboration and Leadership: Successfully established and managed collaborative efforts with external collaborators, enhancing research efficacy and outcomes.🏆 Accomplishments: Notably identified significant research hits and garnered recognition for fostering productive collaborations with external partners.

At the Stanford Research Institute, where I worked as a biologist from 2003 to 2006, I had the invaluable opportunity to immerse myself in dynamic in vivo studies. My three-year journey was characterized by a commitment to advancing scientific knowledge in this field. Here are some key aspects of my experience:🔬 Conducted in-depth in vivo studies, exploring intricate biological processes.🔍 Designed and executed experiments, employing cutting-edge methodologies to gather precise data.📊 Analyzed complex data sets, deriving meaningful insights and trends to advance scientific understanding.🧪 Collaborated closely with interdisciplinary teams, fostering a synergistic environment for innovative research.📄 Published research findings in reputable scientific journals, contributing to the dissemination of knowledge within the community.

Menlo Park, California, United States

During my tenure at SRI International in Menlo Park, CA, spanning from 2002 to 2006, I assumed the role of Biologist I in the Mammalian Toxicology division. My contributions encompassed a wide range of tasks and accomplishments:🐾 Diverse Study Execution: Successfully conducted toxicology, efficacy, dose escalation, pharmacokinetics (PK), and pharmacodynamics (PD) studies within stipulated timeframes and budgets.💉 Expertise in Animal Procedures: Proficiently performed blood collection and diverse dosing techniques on both small and large animals. Demonstrated adeptness in various dosing procedures, such as I.V., PO, SC, IP, IM, and IN in rodents.🏥 Animal Care and Surgery Assistance: Provided routine animal care and supported both large and small animal surgical procedures, showcasing versatility in contributing to various stages of research.🔬 Histology and Cell Preparation: Prepared histology samples and conducted meticulous cell washing, ensuring the quality of research materials.📜 Compliance and Record Keeping: Carried out all studies in adherence to Good Laboratory Practice regulations, maintaining meticulous records to uphold research integrity.🤝 Collaboration and Support: Collaborated closely with investigators to resolve study-related challenges and facilitate smooth operations. Assisted personnel in study procedures, furthering a cooperative research environment.👩‍🏫 Training and Mentorship: Trained entry-level staff in necropsy procedures and various dosing techniques, contributing to their skill development and enhancing team expertise.🩸 Blood Collection Proficiency: Executed various blood collection methods, including remote observation (RO) blood collection in rodents, venipuncture in rabbits, and cephalic collection in dogs.🏆 Accomplishments: Recognized with a "Spot Award" for completing a critical project ahead of schedule and under budget, showcasing exceptional dedication and performance.

During my tenure at Hyseq Pharmaceuticals in Sunnyvale, CA, spanning from 1997 to 2002, I held the role of Research Associate II in the Hybridization department. My contributions and accomplishments during this period include:🧪 Experiments Setup and Execution: Effectively organized and executed experiments as per schedule, demonstrating strong organizational skills and a commitment to research timelines.🧬 Oligo Labeling and Isotope Management: Conducted oligo labeling using radioactive isotopes, maintaining meticulous records for isotope utilization and waste management.📚 Library Sequencing and High-Throughput Screening: Utilized an Automated High-Throughput (HTP) screening platform on a robotic system to sequence cDNA libraries. Proficiently operated and manipulated the robotic system for high-throughput microarray experiments.🔬 Molecular Techniques: Executed PCR experiments and Gel Electrophoresis using SDS-PAGE, skillfully identifying and resolving sample quality issues to ensure smooth production flow and meet project deadlines.🏆 Accomplishments: Received recognition in performance reviews for my collaborative work ethic and leadership qualities, showcasing dedication to team efforts and effective communication skills.📈 Process Improvement: Played a pivotal role in enhancing the quality of filter production. Contributed to refining the process, resulting in fewer steps and reduced error rates, enhancing overall efficiency.🧹 Laboratory Reorganization: Successfully reorganized the media area, focusing on improving lab safety and creating a user-friendly environment for better workflow and productivity.