Haoran Li

Haoran Li Email and Phone Number

Chief Editor and Partner @ Cambridge, MA, US
Cambridge, MA, US
Haoran Li's Location
Cambridge, Massachusetts, United States, United States
Haoran Li's Contact Details

Haoran Li personal email

n/a
About Haoran Li

Highly self-motivated, detail-oriented and innovative biochemist with over 15 years’ experience. Strong ability to collaborate and work in a team environment on interdisciplinary projects. Extensive experience in managing multiple projects simultaneously. Excellent written and communication/interpersonal skills. Proven track record of publications in prestigious journals. Permanent Resident of US. Core Competences: • Hands-on experience in protein biochemistry, enzymology, biophysics• Analytical studies for proteins or complexes (Chromatography, Spectroscopy, MS etc.)• New targets identification for oncology and immune-oncology• SAR and MOA studies of selected inhibitors• Assay development, high-throughput screening (HTS), hit identification and lead optimization • Scientific data review for project decision• Application of cutting-edge technology and strategy for early drug discovery

Haoran Li's Current Company Details
North American Nutri-Sciences Health Consulting Corp.

North American Nutri-Sciences Health Consulting Corp.

Chief Editor and Partner
Cambridge, MA, US
Haoran Li Work Experience Details
  • North American Nutri-Sciences Health Consulting Corp.
    Chief Editor And Partner
    North American Nutri-Sciences Health Consulting Corp.
    Cambridge, Ma, Us
  • North American Nutri-Sciences Health Consulting Corp.
    Chief Editor & Partner
    North American Nutri-Sciences Health Consulting Corp. Oct 2016 - Present
  • Kymera Therapeutics
    Principal Scientist
    Kymera Therapeutics Jan 2022 - May 2022
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  • Kymera Therapeutics
    Associate Principal Scientist
    Kymera Therapeutics Jan 2021 - Dec 2021
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  • Kymera Therapeutics
    Senior Scientist
    Kymera Therapeutics Jan 2018 - Dec 2020
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  • Zhejiang University
    Adjunct Specialist
    Zhejiang University Jan 2017 - Dec 2019
    Hangzhou, Zhejiang, China
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  • Takeda Oncology
    Scientist
    Takeda Oncology Mar 2016 - Dec 2017
    Cambridge, Ma
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  • Boston Biomedical
    Scientist
    Boston Biomedical Oct 2014 - Jan 2016
    Cambridge, Ma
  • Mit
    Postdoctoral Fellow
    Mit Aug 2012 - Sep 2014
    Advisor: Prof. JoAnne Stubbe• Collaborated with 10+ scientists from 4 institutes on 2 projects resulting in 4 papers (3 first-authored papers).• Optimized purification strategy and developed activity assay (in vitro and in vivo) for human ribonucleotide reductase (RNR), which is an important target of anticancer therapy.• Established the correlation between the interconversions of different human RNR quaternary structures and the corresponding activity changes, using a combined study of SAXS, cryo-EM and activity assay.• Discovered the key players for human RNR cofactor assembly, in collaboration with NIH.• Uncovered the key role of evolutionary conserved Dre2-Tah18 complex in the cofactor assembly of yeast RNR, shedding light on the mechanism of human RNR cluster assembly.• Revealed the mechanism of manganese (Mn) cytotoxicity on yeast RNR, providing a new strategy for human RNR inhibitor development.
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  • University Of South Carolina
    Postdoctoral Fellow
    University Of South Carolina Jan 2012 - Jul 2012
    Advisor: Prof. Caryn E. Outten• Elucidated the mechanism of Aft2 (iron-responsive factor) regulation by Grx3-Fra2 complex in yeast iron signaling, filling the gaps in the fundamental understanding of maintaining normal iron metabolism.• Investigated Grx3-Fra2 interaction with 1H-15N 2D HSQC NMR.
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  • University Of South Carolina
    Research Assistant
    University Of South Carolina Jun 2007 - Dec 2011
    Advisor: Prof. Caryn E. Outten• Collaborated with 20 scientists from 10 institutes on 4 projects resulting in 6 papers (5 first-authored papers).• Unraveled the unprecedented iron-sulfur (Fe-S) cluster-mediated interaction between glutaredoxins (Grxs) and BolA-like proteins from different organisms, such as yeast Grx3-Fra2 complex.• Determined the essential role of Grx3-Fra2 complex in regulating yeast iron homeostasis. • Investigated Grx3-Fra2 interaction with 1H-15N 2D HSQC NMR.• Elucidated the mechanism of Aft2 (iron-responsive factor) regulation by Grx3-Fra2 complex in yeast iron signaling, filling the gaps in the fundamental understanding of maintaining normal iron metabolism.• Characterized various anaerobically-purified Fe-S proteins using multiple biophysical methods.
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Haoran Li Skills

Molecular Cloning Biochemistry Enzyme Kinetics Enzyme Assays Biophysics Molecular Biology Genetics Cell Biology Protein Expression And Purification Surface Plasmon Resonance Nmr Spectroscopy Uv/vis Circular Dichroism Epr Endor Western Blotting Nmr Uv/vis Spectroscopy Mammalian Cell Culture Immunoprecipitation Protein Expression Cell Culture Protein Chemistry Purification Spectroscopy Nuclear Magnetic Resonance In Vivo Research Saxs Bacterial Cell Culture Htrf Resonance Raman Mossbauer Activity Based Protein Profiling Delfia Time Resolved Fluorescence Assay Alphalisa/alphascreen Thermal Shift Assay In Vitro

Haoran Li Education Details

Frequently Asked Questions about Haoran Li

What company does Haoran Li work for?

Haoran Li works for North American Nutri-Sciences Health Consulting Corp.

What is Haoran Li's role at the current company?

Haoran Li's current role is Chief Editor and Partner.

What is Haoran Li's email address?

Haoran Li's email address is ha****@****eda.com

What schools did Haoran Li attend?

Haoran Li attended Nanjing University, University Of South Carolina-Columbia.

What skills is Haoran Li known for?

Haoran Li has skills like Molecular Cloning, Biochemistry, Enzyme Kinetics, Enzyme Assays, Biophysics, Molecular Biology, Genetics, Cell Biology, Protein Expression And Purification, Surface Plasmon Resonance, Nmr Spectroscopy, Uv/vis.

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