David Holmes Email and Phone Number
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Creative technologist with 20+ years of experience developing technologies and commercializingcomplex Platform Technologies that combine microfluidics, optics, electronics, precision mechanicaland control systems, software, assays, algorithms, and data analysis. Proven leadership skills and Executive level management experience. Experience leading all aspects of product development life-cycle: from ideation through to devt.,verification and validation, transfer to manufacture, successful launch, and product extensions. Experienced at performing complex problem solving and troubleshooting using robust engineeringtechniques, working with cross-functional teams (including Chemists and Assay scientists,Consumable, Software/Hardware engineering, Bio-informatics and Service teams). Experienced in managing third party suppliers, manufacturing partners and engineering consultanciesand contractors. Track-record of creating, growing and leading highly productive R&D, Manufacturing and Serviceteams from the ground up. Strategic leader who partners cross-functionally to implement best-in-class engineering and designstandards, enhancing organizational performance through clear communication and collaboration. Executive team member with proven ability at leading organization-wide initiatives. Significantly elevates standards through collaborative planning and transparent communicationacross all levels.
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Vice President Of Product DevelopmentCell Microsystems Feb 2024 - PresentDurham, Nc, Us- Member of the executive leadership team, responsible for driving and overseeing all aspects of hardware and consumables development, software engineering and manufacturing for Cell Microsystems' range of life science instruments platforms. - Responsible for setting the strategic direction, in conjunction with other functional team leaders, ensuring the successful execution of new product development initiatives. - Drawing upon extensive background in opto-mechanics, software engineering, start-up experience, and expertise in life science instrument development, - Leading cross-functional teams to achieve company's objectives and remain at the forefront of technological innovation. -
Vice President Discover Platform1859 Apr 2023 - Feb 2024San Diego, California, Us- Member of the Senior Leadership Team with overall Operational responsible for 1859's Discovery Platform. -
Vice President Of Engineering1859 Oct 2020 - Apr 2023San Diego, California, Us- Member of the Senior Leadership Team with responsible for Engineering development of 1859's Discovery Platform.- Technical oversight of screening operations.- Leading engineering and technology development for a microfluidic droplet-based drug encoded library screening platform – overall responsibility for system instrumentation HW/SW and cartridge consumable R&D.- Building and managing Engineering group.- Managing partnerships with 3rd party suppliers, manufacturers and engineering consultants. -
Principal EngineerSingular Genomics Aug 2019 - Sep 2020San Diego, California, Us -
Director / Head Of Physics And EngineeringSphere Fluidics Limited Aug 2013 - Aug 2019Great Abington, Cambridge, Gb• Core Team Leader, Technology Lead and Programme Manager for Cyto-Mine® product development. - Led the development of Sphere’s core product, the Cyto-Mine® single cell analysis and isolation system. • Responsible for driving the development, management, verification and validation of user & system requirements.• Managing internal and external engineering resources. - Direct responsibility for the HW and SW development within the company, managing the in-house engineering team (10 engineers and scientists) and external technology and manufacturing partners.• Responsible for multi-million £ programme budget over the last 5 years.• Managed transfer to manufacture of instrument and microfluidic consumable.• Reporting programme progress monthly to senior management (director and board level) at programme review meetings.• I am responsible for engineering activity and technical decision making: - Leading technical meetings and discussions- Assessing, mitigating and retiring technology risks- Leading defect management (cross functional assignment, prioritization, tracking and verification)- Performing root cause analysis and designating corrective actions- Developing and validating of new test methods- Track engineering team progress against KPIs• Established and manage the companies service engineering infrastructure, this includes:- Implementing a web-based service portal / ticketing system accessible by customers- Coordinate installation and servicing at customer sites worldwide• Worked closely with commercial and business development teams, presenting to customers, supporting selling and development of new business opportunities.• Manage distributor training and technical support including training materials.• Experienced working within QMS (e.g. ISO9001).• Experience of taking products through conformance testing (e.g. EMC/ESD, safety assessment, CE marking, CB scheme, UL).• Team building, line management, mentoring of staff. -
London Centre For NanotechnologyUcl Nov 2009 - Aug 2013London, Greater London, GbVisiting Researcher / UCL Enterprise Fellow 05/2012 – 07/2013London School of Hygiene and Tropical Medicine (LSHTM), UK• develop and test microfluidic devices for isolation of P.falcipurum from malaria infected blood• work with Sony DADC to prototype polymer devices• engage with and transfer technology from nanotech to LSTHMSenior Research Associate 11/2009 – 07/2013London Centre for Nanotechnology, University College London, UK• R&D scientist in large (£2M) interdisciplinary consortium to develop multi-marker diagnostics• design, fabricate and test microfluidic devices for isolation, concentration and detection of HIV markers form blood (virus, CD4+ T-cells, viral RNA)• develop mechanical, electrical and optical, methods of virus and cell manipulation (e.g. deterministic lateral displacement, dielectrophoresis, whispering gallery mode sensors) -
Mrc Discipline Hopping FellowUniversity Of Southampton Nov 2008 - Oct 2009Southampton, Hampshire, Gb- Personal fellowship awarded by the Medical Research Council to move my work to the School of Medicine to pursue research in the area of microfluidics and impedance cytometry in a bio-medical setting.- Technology transfer / immersion with bio-medical scientists and clinicians- Patent filed on use of dielectric labels for impedance based cell discrimination -
Senior Postdoctoral Research FellowUniversity Of Southampton Nov 2003 - Oct 2008Southampton, Hampshire, GbProjects:- On-chip Differential Blood Analysis: Proof-of-concept project funded by Philips, UK: assessment of microfluidic impedance cytometer for label-free analysis and identification of leukocyte subtypes (basophils, eosinophils, neutrophils, monocytes and lymphocytes). Benchmarking impedance cytometry against “gold standard” of FACS for differential bloodanalysis. Construct multi-colour confocal fluorescence imaging system for high-throughput single cellmeasurement in microfluidic device. Develop control and analysis software for impedance/optical flowcytometer.- 4G sequencing the genome in a day: development of microfluidic and optical methods for rapid sequencing and immuno assay detection platform.- High-Speed Label-Free Single Cell Impedance Cytometry: design and construct a microfluidic single cell impedance system (10-15 Farad sensitivity). Particular emphasis on cell discrimination (e.g. bacteria, yeast, blood, algae). Design and construct of three-colour fluorescence confocal microscope. Development software for data capture and analysis of optical and impedance signals -
Postdoctoral Research AssistantUniversity Of Glasgow Apr 2002 - Oct 2003Glasgow, Glasgow, GbDeveloped optical and electrical methods for sorting and analysing cells and other microscopic objects using mcrofluidic devices. -
Phd StudentUniversity Of Glasgow Oct 1998 - Mar 2002Glasgow, Glasgow, Gb
David Holmes Skills
David Holmes Education Details
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University Of GlasgowBioelectronics -
University Of GlasgowNeuroscience -
University Of GlasgowElectronics And Electrical Engineering
Frequently Asked Questions about David Holmes
What company does David Holmes work for?
David Holmes works for Cell Microsystems
What is David Holmes's role at the current company?
David Holmes's current role is VP, Product Development at Cell Microsystems Inc..
What is David Holmes's email address?
David Holmes's email address is da****@****l.ac.uk
What schools did David Holmes attend?
David Holmes attended University Of Glasgow, University Of Glasgow, University Of Glasgow.
What skills is David Holmes known for?
David Holmes has skills like Nanotechnology, Microfluidics, Cell Culture, Microfabrication, Cell, Cell Biology, Mems, Optics, Spectroscopy, Matlab, Microscopy, Fluorescence Microscopy.
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