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With extensive experience in developing viral vaccine, oncolytic virus, viral vector and antiviral drug from concept to clinical evaluations and commercialization, I am passionate to bring biological products to patients. • I have pioneered reverse genetic systems for influenza, respiratory syncytial virus (RSV), and Newcastle disease virus (NDV) for vaccine characterization and manufacture. I have contributed to progress several candidate drugs to clinical evaluations and commercial production such as NDV oncolytic virus (Phase 1), live attenuated RSV vaccine and influenza pandemic vaccines (Phase 1), anti-RSV mAb (Phase 3), and commercial live attenuated influenza vaccine (FluMist).• My scientific and management leadership enabled the company to be the first to deliver the 2009 influenza pandemic vaccine to the market. • My accomplishments are reflected in pipeline progression, excellent track records in getting grants, patents (>12), scientific publications (>100), and numerous conference presentations.
Cyanvac
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Chief Scientific OfficerCyanvac Sep 2020 - PresentLead the effort in developing COVID-19 vaccine and RSV vaccine based on a novel intranasal vaccine platform.
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Sr. Director • Fellow Of R&DAstrazeneca Apr 2019 - May 2020Cambridge, Cambridgeshire, GbManaged a multi-functional team in Translation Science to support various clinical programs. • Determined susceptibility of circulating RSVs from global RSV surveillance study to the anti-RSV drug for launch of Phase 3 trials.• Progressed NDV oncolytic viruses from preclinical tox study to IND filing and phase 1 trial.• Uncovered drug mechanisms of actions (MOA) and drug target through genomic sequencing of viruses, bacteria (microbiome) and TCR repertoire from clinical studies. -
Director/Sr. Director • Fellow Of Infectious Disease/Vaccine ResearchMedimmune Dec 2001 - Mar 2019Gaithersburg, Maryland, Us• Developed annual commercial FluMist vaccine production process by reverse genetics and contributed to the BLA filing for FluMist commercialization and annual FluMist compaign.• Developed and evaluated multiple influenza pandemic vaccine candidates (H1, H2, H5, H6, H7, H9) in phase 1 clinical trials as a co-Principal Investigator with the NIH. • Conceptualized a novel NDV oncolytic virus platform for cancer therapy by designing and creating the oncolytic virus candidates for Phase 1 trials.• Created an alphavirus replicon system for cancer vaccine under preclinical evaluation. -
Sr. Scientist Of Vaccine ResearchAviron Apr 1997 - Dec 2001• Built the Respiratory Virus group to generate recombinant RSV vaccine (phase 1).• Developed reverse genetic systems for influenza type A and B viruses and applied to annual influenza vaccine (FluMist) production. • Contributed to the BLA filling of live attenuated influenza vaccines (FluMist).
Hong Jin Skills
Hong Jin Education Details
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Northwestern UniversityVirology In Influenza Virus -
University Of GlasgowVirology -
Beijing University Of Medical SchoolVirology -
Chongqing UniversityMedicine
Frequently Asked Questions about Hong Jin
What company does Hong Jin work for?
Hong Jin works for Cyanvac
What is Hong Jin's role at the current company?
Hong Jin's current role is viral vaccine.
What is Hong Jin's email address?
Hong Jin's email address is ji****@****une.com
What is Hong Jin's direct phone number?
Hong Jin's direct phone number is +165060*****
What schools did Hong Jin attend?
Hong Jin attended Northwestern University, University Of Glasgow, Beijing University Of Medical School, Chongqing University.
What skills is Hong Jin known for?
Hong Jin has skills like Virology, Vaccines R&d, Molecular Biology.
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