• Acquired ChemoCentryx• Designed and synthesized compounds to improve novelty, potency, and properties for programs in oncology and inflammation.• Assumed leadership role for medicinal chemistry project, overseeing team of three chemists. Designed novel molecules, coordinated evaluation of these compounds in collaboration with colleagues in biology and DMPK.

• Supported successful execution of six medicinal chemistry campaigns.• Assisted in project selection process. Researched novel targets and synthesized literature molecules known to modulate desired targets.• Led two medicinal chemistry projects, coordinating synthesis of molecules among chemistry team and evaluation by collaborators in biology and DMPK.• Played a crucial role in scale-up campaigns of three development candidates, including the clinical candidate CCX559.• Served as co-inventor on seven published patent applications, along with additional unpublished application. Organized experimental data and worked closely with legal department to complete applications.

Developed novel method for synthesizing fused bicyclic nitrogen heterocycles via rhodium-catalyzed C-H functionalization.

• Adapted synthesis of clinical candidate to be performed on kilogram scale under GMP conditions for oncology clinical trial.• Designed and synthesized compounds for lead optimization in oncology program.• Evaluated synthetic compounds in vitro and in cell culture; worked with colleagues in biology for advanced evaluation.• Co-authored five publications and one review; co-inventor on two patent applications.

Developed efficient dual functionalization of aromatic carboxylic acids.

Synthesized substrates and catalysts for N-heterocyclic carbene-catalyzed reactions.

Synthesized peptides via solid-phase synthesis for use as molecular probes.