Hugh Graham

Hugh Graham Email and Phone Number

Director, Cell Culture Sciences at MacroGenics, Inc. @ MacroGenics, Inc.
Hugh Graham's Location
Rockville, Maryland, United States, United States
Hugh Graham's Contact Details
About Hugh Graham

Biochemical engineer and leader with extensive experience in upstream and downstream protein production for research, pre-clinical and cGMP production applications. Experienced team manager and project leader, motivated to bring drug candidates and products to the clinic and market and to optimize commercial processes.Specialties: GMP biologics manufacturing and recombinant protein expression. Fermentation and cell culture production with multiple expression systems. Process development and downstream unit operations. Cell line and media development. Process technical transfer, CMO and outsourcing coordination. Regulatory support (inspections, CMC for BLA and IND, HA responses), process validation, project management, documentation and presentation skills.

Hugh Graham's Current Company Details
MacroGenics, Inc.

Macrogenics, Inc.

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Director, Cell Culture Sciences at MacroGenics, Inc.
Hugh Graham Work Experience Details
  • Macrogenics, Inc.
    Director, Cell Culture Sciences
    Macrogenics, Inc. May 2018 - Present
    Rockville, Md, Us
    Developing and leading a group of scientists and engineers, supporting a fast-moving pipeline of antibody-based therapeutics.Group activities include cell line development, cell culture process development, tech transfer, regulatory filing authoring and support, external partner interactions and in-house and external manufacturing support.
  • Bristol-Myers Squibb
    Associate Director, Manufacturing Technology
    Bristol-Myers Squibb Aug 2016 - Oct 2017
    Lawrence Township, Nj, Us
    Leading the Manufacturing Technology group in support of cell culture, purification and drug substance handling operations for commercial biologics manufacturing.
  • Bristol-Myers Squibb
    Associate Director, Ds Ms&T Syracuse - Upstream
    Bristol-Myers Squibb Jun 2013 - Jul 2016
    Lawrence Township, Nj, Us
    I led the upstream Manufacturing Sciences and Technology group in Syracuse. We support commercial and late stage clinical manufacturing at Syracuse and at third party sites. Led process improvement projects, lab studies, authored and reviewed CMC documentation, and supported manufacturing investigations.
  • Bristol-Myers Squibb
    Senior Scientist
    Bristol-Myers Squibb Feb 2012 - Jun 2013
    Lawrence Township, Nj, Us
    Process life cycle management in Manufacturing Sciences and Technology. Supported the drug substance manufacturing process for a commercial biologic and helped move a late-stage clinical molecule towards commercial production.
  • Bayer Healthcare
    Senior Process Development Engineer
    Bayer Healthcare Sep 2008 - Feb 2012
    Leverkusen, North Rhine-Westphalia, De
    Executed process improvement and capital projects, expanded lab facilities, provided regulatory inspection support, and performed daily manufacturing support for commercial upstream production.
  • Raven Biotechnologies, Inc
    Head Of Upstream Manufacturing
    Raven Biotechnologies, Inc Jul 2005 - Jul 2008
    Us
    Upstream manufacturing of monoclonal antibodies at Raven incorporated mammalian cell line development, process and media development and coordination of outsourced work and contract manufacturing. My group of 4 people also has some research responsibilities and I co-lead an IND candidate development project.
  • Exelixis
    Senior Scientist
    Exelixis 1999 - 2005
    Alameda, California, Us
    Worked on multiple projects in the fields of oncology, agbio and metabolism. Ran a team which produced reagent proteins using baculovirus, bacterial and mammalian expression systems as part of a department supplying material for crystallography and HTS uses. Team used glass, stainless and disposable fermentor systems up to 80L in scale. Coordinated outsourcing of larger scale production.
  • Metaxen Llc
    Scientist
    Metaxen Llc Jul 1998 - Jul 1999
    Produced and purified recombinant reagent proteins using E. coli and column chromatography. Executed activity assays. Designed and established a lab in a new building.

Hugh Graham Skills

Gmp Technology Transfer Cell Culture Biotechnology Biopharmaceuticals Fermentation Pharmaceutical Industry Validation Protein Chemistry Fda Drug Discovery Life Sciences Cell Monoclonal Antibodies Biochemistry Drug Development V&v Purification Clinical Development Commercialization High Throughput Screening Oncology Laboratory Capa Cgmp Protein Expression Lifesciences Chromatography Change Control Bioreactor Lims Process Development Pharmaceuticals 21 Cfr Part 11 Gxp

Hugh Graham Education Details

  • Colorado State University
    Colorado State University
    Chemical Engineering
  • University Of Surrey
    University Of Surrey
    Chemical Engineering

Frequently Asked Questions about Hugh Graham

What company does Hugh Graham work for?

Hugh Graham works for Macrogenics, Inc.

What is Hugh Graham's role at the current company?

Hugh Graham's current role is Director, Cell Culture Sciences at MacroGenics, Inc..

What is Hugh Graham's email address?

Hugh Graham's email address is hu****@****ail.com

What is Hugh Graham's direct phone number?

Hugh Graham's direct phone number is +1 212-546*****

What schools did Hugh Graham attend?

Hugh Graham attended Colorado State University, University Of Surrey.

What skills is Hugh Graham known for?

Hugh Graham has skills like Gmp, Technology Transfer, Cell Culture, Biotechnology, Biopharmaceuticals, Fermentation, Pharmaceutical Industry, Validation, Protein Chemistry, Fda, Drug Discovery, Life Sciences.

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