Developing and commercializing continuous-flow lipid nanoparticle manufacturing platforms for enabling mRNA-based vaccines, targeted therapeutics, and precision drug delivery.

Developing the next generation biomarker and diagnostics platform, based on rapid, portable Raman spectroscopy and Deep Learning.

Scalables designs, manufactures and markets a scalable, easy-to-use laboratory instrumentation platform that combines the ability to easily create new setups with the power of AI to revolutionize lab experimentation in the biomedical industry.

Providing critical assistance to startup and medium-scale companies within diagnostics and healthcare markets in commercializing new products -- moving them from concept to feasibility demonstration and to commercial launch.

NIH invested significant amount of money and resources in diagnostic companies, in order to get ahead of the national testing needs for COVID-19. My team's job was to guide fledgling startups from concept to large-scale commercialization, providing along the way assistance with technology de-risking, manufacturing/vendor assistance, regulatory and quality guidance, business planning and go-to-market strategies. The scale of the RADx (Rapid Acceleration of Diagnostics) program was quite extensive -- well suited to matching the enormous challenge of providing testing capacity for testing the entire population of the nation every 10-14 days.

Savran is advancing the cutting-edge in the field of liquid biopsy. The company’s main technology enables rapid enumeration (~1 hour) and extraction of extremely rare cells from whole blood without any complicated pre-processing.The technology is already successfully applied to monitoring of circulating tumor cells (CTC’s) in oncology patients during and after a course of chemotherapy. It is also being applied to the isolation of pre-natal cells in mothers’ blood for early determination of genetic abnormalities.

Developing and commercializing ground-breaking diagnostic platforms for the sensitive and early detection and quantification of neurodegenerative disease biomarkers.

Ancera is currently applying a novel cell-manipulation platform (MagDrive) that I invented to revolutionize the food safety market — both by dramatically shortening bacterial presence assays and by providing previously unavailable, game-changing capabilities to the food production and packaging industry. The technology uses ferrofluids to enable the rapid and label-free manipulation, separation, concentration and capture of bacteria and other target cells within a complex sample in the presence of high background (other similar cells, particulates, etc.). MagDrive is well suited to rapidly finding and identifying rare cells in application spaces other than food safety as well, including detecting bacteria in blood (for sepsis diagnosis), circulating tumor cell detection and enumeration, and stem-cell isolation from blood.Accomplishments as a Co-founder and CTO:* Built all the functional instrument prototypes, demonstrating MagDrive's commercial promise.* Inventor, mechanical designer and lead architect of the high-throughput, multi-assay (micro)fluidic disposable cartridges that are currently being commercialized.* Qualified external vendors for the supply of both OEM and custom components. Trained certain vendors on achieving specific dimensional and performance metrics on their custom parts. Established custom quality control metrics for these vendors to implement to meet our specs.* Guided the technology transfer effort into both external manufacturing vendors, as well as the internal engineering and biology team during the Series A funding phase.* Maintained the IP portfolio of the company -- successfully responding to office actions, handling attorney communications, providing new invention disclosures.* Won multiple SBIR grants and led our internal research efforts as the Principal Investigator.* Inventor of many additional technologies that support ferrofluid-mediated biological assays.

* Conducted internationally recognized, leading research on Nanotechnology and micro-scale phenomena: - pumping and bio-assays in ferrofluids (inventor of MagDrive), - nano-colloidal suspension physics (discoverer of numerous ferrofluidic phenomena), - wide-bandwidth micro-scale energy generation/harvesting (developed non-linear energy harvesting concepts into the widely recognized research field it is today), - bacterial upstream motility (discoverer of positive rheotaxis in bacteria);* Taught undergraduate and graduate level courses in Electrical Engineering;* Advised undergraduate, graduate and postdoctoral students;

Developed a simple, low-cost research setup for the study of bacterial chemotaxis.

Designed, developed, helped fabricate and characterized a micro-scale magnetic generator that was designed to go within a shirt-button sized jet engine. This project was supported by the Department of Defense.

• Characterized the switching dynamics of magnetic tunneling junctions in a research group developing magnetic random access memory (MRAM) cells.• Predicted and demonstrated the conditions for faster-than-GHz operating speeds with the memory cells.• Authored a fully 3D magnetics simulation program from scratch (with MATLAB and compiled code) to elucidate the dynamics of magnetization reversal in MRAM cells. The program proved to be faster and more accurate than the expensive commercial alternative.