Hwoi Chan Kwon Email and Phone Number
As a biophysics PhD candidate at UC Davis, I have conducted research on the molecular mechanisms of ion channel function and regulation. My current project focuses on the slow gating of CLC-0—a prototype chloride channel in the CLC family—and its modulation by intracellular protons. Using patch-clamp electrophysiology and fluorescence microscopy, I've discovered and characterized a novel inactivation mechanism of CLC-0.I'm also a teaching assistant for UC Davis biochemistry courses and teach the fundamentals of protein structure, function, and metabolism, in addition to the concepts behind biochemical techniques.
National Institute Of Neurological Disorders And Stroke (Ninds)
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Postdoctoral FellowNational Institute Of Neurological Disorders And Stroke (Ninds)Bethesda, Md, Us -
Postdoc FellowNational Institute Of Neurological Disorders And Stroke (Ninds) Sep 2024 - PresentBethesda, Maryland, United States -
Teaching Assistant - BiochemistryUniversity Of California, Davis Mar 2018 - Mar 2024Instructed over 100 undergraduate students in biochemistry fundamentals, teaching theoretical laboratory techniques such as column chromatography and gel electrophoresisStrategically aligned teaching methods with core biochemistry concepts on structure, function, and metabolism, leading to an increase in performance metrics.Facilitated engaging discussions and developed comprehensive supplementary materials, increasing student engagement. -
Intellectual Property/Tech Transfer Science InternUniversity Of California, Davis Sep 2019 - Dec 2019Assisted in preparing and submitting Reports of Invention (ROI) for UC Davis Innovation Access to facilitate commercialization processesConducted comprehensive technical research to assess potential conflicting inventions; identified possible overlaps in intellectual property that may lead to USPTO patent submission rejection. Drafted non-confidential marketing and licensing materials; communicated the value proposition of inventions to potential partners and investors -
Graduate Student ResearcherUc Davis Center For Neuroscience Sep 2016 - Mar 2024DavisGenerated novel mutations using recombinant DNA technology by designing primer oligo for site-directed mutagenesis, performing polymerase chain reaction, transforming E.Coli using heat-shock and electroporation, amplifying plasmid vector, mini prepping plasmid, and quantifying nucleic acid using UV-Vis spectroscopy.Experienced in culturing, harvesting, and prepping various expression systems ranging from adherent mammalian cell lines, such as HEK293 and CHO to X. laevis oocytes. Performed lipid-based transient transfection for heterologous expression in the mammalian cell line within the guidelines of a biosafety level 2 (BSL-2) environment; performed manipulation and injection of X. oocytes with mRNA load using the nanoliter injection system.Identified and quantified heterologous expression and activity of recombinant protein using wide-field fluorescence, total internal reflection fluorescence (TIRF), and fluorometry.Designed and performed patch-clamp electrophysiology using pCLAMP to generate thousands of high-quality recording traces using voltage and current clamp protocols, leading to the discovery of a novel gating mechanism for a CLC channel.Performed and analyzed two-electrode voltage clamp (TEVC) and single-channel recordings in quantifying macroscopic and microscopic properties of ion channels. Analyzed electrophysiology data using regression and statistical methods on Clampfit, excel, and Originlab (analogous to Graphed).Wrote technical papers and reviews and collaborated on original research, as demonstrated by first and second author publications. -
Teaching AssistantPacific Union College Sep 2014 - Jun 2016 -
Undergraduate Student ResearcherPacific Union College Jun 2014 - Jun 2016
Hwoi Chan Kwon Skills
Hwoi Chan Kwon Education Details
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Biophysics -
Biochemistry
Frequently Asked Questions about Hwoi Chan Kwon
What company does Hwoi Chan Kwon work for?
Hwoi Chan Kwon works for National Institute Of Neurological Disorders And Stroke (Ninds)
What is Hwoi Chan Kwon's role at the current company?
Hwoi Chan Kwon's current role is Postdoctoral Fellow.
What schools did Hwoi Chan Kwon attend?
Hwoi Chan Kwon attended University Of California, Davis, Pacific Union College.
What skills is Hwoi Chan Kwon known for?
Hwoi Chan Kwon has skills like Event Planning, Teaching, Microsoft Word, Research, Higher Education, Community Outreach, Electrophysiology, Fluorescence Microscopy, Cell Culturing.
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