I. Scott Ramsey Email and Phone Number

Premedical, Predental, and Graduate Higher Education/Health Career Professional Advising:September 2020 - presentDirector, VCU Premedical Graduate Sciences Certificate Program (CERT)https://medschool.vcu.edu/education/certificate_programs/premed_cert/Academic Research: Ion Channel Discovery & Function-Structure Investigation:Oct 2008 - presentAssistant ProfessorDepartment of Physiology and BiophysicsVirginia Commonwealth University School of MedicineRichmond, VA● Function and structure of ion channel and transporter proteinsSept 2001 – Oct 2008Harvard Medical School, Children’s Hospital, Boston, MA; Research FellowPrincipal Investigator: David E. Clapham, MD, PhD● Identification and characterization of the Hvcn1 gene encoding the voltage-gated proton channel Hv1● Identification and characterization of the Ca2+-permeable and temperature-sensitive channel TRPV3● Cloning and expression of sperm-specific channels CatSper3 & CatSper4● Rac, PI3-kinase and PI5-kinase-dependent regulation of TRPC5 channels● Development of a method to visualize calcium entry by fluorescence translocation in live cellsSept 1995 - Aug 2001Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN; Graduate StudentThesis Advisor: Louis J. DeFelice, PhD● Neurotransmitter (5-HT, NE, DA) transporter pharmacology and biophysicsDoctoral Thesis: “Modulation of Serotonin Transporter Function and Pharmacology by Subunit Interactions and an Endogenous Regulatory Factor”June 1989 - Dec 1994Syntex Discovery Research, Institute of Pharmacology, Palo Alto, CA; Biologist IISupervisors: Robert Alvarez, PhD and Richard Eglen, PhD● Identification and pharmacological characterization of novel G-protein coupled serotonin receptors (5-HT4, 5-HT7) expressed in mammalian rodent CNSSpecialties: Techniques: mammalian cell patch clamp and oocyte TEVC electrophysiology, molecular cloning, enzyme biochemistry & radioligand binding, time-resolved confocal and TIRF microscopy, antibody deisgn, Western blotting & immunocytochemistry, primary neuronal an mammalian cell culture