Ian Dailey Email & Phone Number

Saint Paul, Mn, Us

Greater Minneapolis-St. Paul Area

St Paul, Minnesota, United States

St Paul, Minnesota, United States

St. Paul, Mn

St. Paul, Mn

Urbana-Champaign, Illinois Area

During my Ph.D. I led a research team that completed the synthesis of the core structure of all mycosamine-containing polyene macrolides, and was part of a team that synthesized several derivatives of the antifungal polyene macrolide amphotericin B. Using these derivatives, we discovered that this family of clinically vital natural products exerts antifungal activity via a mechanism different from that which has been assumed for the past 50 years. These results have important ramifications for the optimization of the therapeutic index of these compounds, the design of new antibiotics which can overcome microbial resistance, and the development of molecular prosthetics as a fundamentally new manifold for the treatment of human disease.

Developed HPLC quickscreen assay for food animal feed supplements in liver tissue. Optimized method to provide greater recovery and precision, produce half as much waste, and require half as much time as the current company method. Completed method development significantly ahead of schedule. Developed novel separation of β-agonists using Waters ACQUITY UPLC technology.

Designed and tested assays for detecting cofactors of carbohydrate metabolism in E. coli. Organized and planned First Annual Rose-Hulman Undergraduate Research Symposium.

Ph.D., Organic Chemistry

Thesis Advisor: Professor Martin Burke 2011 Abbott Scholar, Abbott Laboratories 2011 Roche Excellence in Chemistry Award Winner 2011 Pines.

B.S, Chemistry

Activities and Societies: Alpha Lambda Delta, Blue Key Honor Society, Chemistry Advisory Board, International Society for Pharmaceutical.