Instruments is an international, peer-reviewed open access journal that provides an advanced forum for studies related to the design and applications of instruments, apparatuses, and experimental techniques in disciplinary and interdisciplinary research.The journal aims at publishing high-quality scientific papers presenting ground-breaking and innovative results, as well as major achievements in the field of instrumentation and in the use of the related data.The main subject areas include:• Innovative, design methods, applications, metrological characterization, and theory of all aspects of advanced instruments• Innovative data acquisition architectures, components, and pre-processing techniques• Instrumentation science: uncertainty theory and application, epistemology, measurement production modeling, and experimental identification and validation• Advanced instrumentation in medicine