Isaac E. Kaba Email and Phone Number
PhD student at UC Berkeley studying chemistry and chemical biology, with interests in developing new chemical tools to manipulate immune system responses, probe cell signaling, and tackle difficult-to-drug, so-called ‘undruggable’ targets.
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Graduate Student ResearcherUniversity Of California, BerkeleyCalifornia, United States -
Graduate Student InstructorUniversity Of California, Berkeley Aug 2024 - Present• Teach (GSI) CHEM 3A (Organic Chemistry I : Chemical Structure and Reactivity)• Lecturer: MaryAnn Robak -
Researcher — Center For Drug Design And Development (Cd3)The University Of Toledo Jan 2024 - Jul 2024• Photoaffinity labeling for target identification• Cancer and CNS drug discovery• Small-molecule hit-to-lead optimization -
Research Assistant — Center For Drug Design And Development (Cd3)The University Of Toledo Aug 2023 - Dec 2023United States• Honors thesis in medicinal chemistry• Thesis titled “Synthesis and Structure-Activity Relationships (SAR) of Novel Dual Mechanism EZH2/AR Inhibitors for Prostate Cancer” -
Remote Research InvestigatorYale University Feb 2023 - Dec 2023• Selected for Yale University’s Biological and Biomedical Sciences (BBS) Next Generation Excellence Initiative Program• Performed remote multi-Omics analysis in human tumor samples, aimed at deepening understanding of the links between metabolism and cancer and identifying novel drug targets for cancer treatment -
Summer InternNovartis Institutes For Biomedical Research (Nibr) May 2023 - Aug 2023Cambridge, Massachusetts, United States• Selected for the Summer of Science Internship Program at the Novartis Institutes for Biomedical Research (NIBR)• Developed an independent project in the Global Discovery Chemistry (GDC) Department. My project involved utilizing synthetic organic chemistry to improve droplet-based microfluidic platforms to screen DNA-encoded libraries against hard-to-drug therapeutic targets. • Performed organic synthesis and purification using ISCO Normal Phase Chromatography, Liquid Chromatography/Mass Spectrometry (LCMS), and High Performance Liquid Chromatography (HPLC).• Presented my research findings as a poster at the Novartis Poster Session -
Lead Investigator — Cancer And Systems Therapeutics (Cast) LabThe University Of Toledo Aug 2022 - May 2023United States• Awarded the 2023 Academic Year Research Program Fellowship for the proposal titled “Design and Synthesis of Novel Thieno-Pyrimidine Derivatives for Triple-Negative Breast Cancer”• Performed small-molecules organic synthesis, purification (Combiflash), and characterization (NMR); Assisted/shadowed graduate students with tumor cell line culture and Western blot protein analysisMentor: Prof. Amit Tiwari (Department of Pharmacology and Experimental Therapeutics) -
Research Assistant — Von Grafenstein LabThe University Of Toledo Sep 2022 - Jan 2023United States• Honors Project/Physiological Chemistry: “Ferroptosis and Lipids Oxidation”• Performed the synthesis and characterization (NMR) of novel small-molecule probes/matrix and proceeded with the detection of oxidized lipids by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF)• Mentors: Prof. Hermann von Grafenstein & Prof. Ghassan Abushaikha (Department of Medicinal and Biological Chemistry) -
Lead Investigator — Abushaika LabThe University Of Toledo May 2022 - Aug 2022United States• Awarded the 2022 Summer Undergraduate Research Fellowship for the proposal titled “Synthesis of Novel PI3Kα inhibitors for cancer therapy”• Performed synthesis, purification and characterization (NMR) of small molecule drug-like analogs• Mentor: Prof. Ghassan Abushaikha (Department of Medicinal and Biological Chemistry) -
Lead Investigator — CesnovUniversity Of Kinshasa Aug 2019 - Dec 2020Kinshasa, Congo (Drc)• Undergraduate Research/Apprenticeship: “Microscopic Features, Antioxidant and Antimicrobial Potencies of Congolese Cosmetopiea’ Medicinal Plants”• Performed phytochemical analysis, plants powder microscopy and DPPH and ABTS free radicals scavenging assays.
Isaac E. Kaba Education Details
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Chemistry -
Gpa 4.0/4.0 (Summa Cum Laude) -
Distinction (First Class Honors)
Frequently Asked Questions about Isaac E. Kaba
What company does Isaac E. Kaba work for?
Isaac E. Kaba works for University Of California, Berkeley
What is Isaac E. Kaba's role at the current company?
Isaac E. Kaba's current role is Graduate Student Researcher.
What schools did Isaac E. Kaba attend?
Isaac E. Kaba attended University Of California, Berkeley, The University Of Toledo, University Of Kinshasa.
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