Isaac Downs Email & Phone Number

Frederick, Md, Us

Specializes in immunology and infectious diseases to streamline research as executive officer and chief of clinical laboratory operations for the Division of Medicine. Serves as a principal investigator managing clinical trial activities and repository functions. Participates in program management as a contracting officer representative and developer of regulatory activities for the Office of Research Technology and Applications. Assist with educational outreach projects and student internship programs.

Atlanta, Georgia

Performed high level qualitative and quantitative data analysis to assist with decision-making processes for regulatory functions. Selected as a collaborator to support consultants in establishing information technology platforms for human subject research and fellowship consolidation. Participated in privacy and confidentiality unit activities and developed training material on regulatory functions involving Paperwork Reduction Act, privacy and confidentiality laws, and information technology.

College Station, Tx

Subject matter expertise in the principle mechanisms regulating immune responses and inflammation. Research scope focused on how antigens are recognized by pattern recognition receptors and subsequent impact on the innate and adaptive immune system. Served as a lab manager in studies regarding tuberculosis, Crohn's disease, multiple sclerosis, and graft versus host disease. Participated in international collaborations in studying evolutionary changes of immune response between species as well as molecular epidemiology research experience relative to 22 different types of human solid tumors.

Shreveport, Louisiana Area

Performed postdoctoral research evaluating how epigenetic changes influence colon and breast cancer. Research approaches included the use of histone deacetylase inhibitors to examine changes in gene expression, post-translational modifications, apoptosis, and cellular survival.

Shreveport, Louisiana Area

Subject matter expertise involved drug-induced liver injury and it’s impact on immunity. Acetaminophen overdose studies determined that invariant natural killer T cells down-regulate antioxidant levels to respectfully promote oxidative/nitrosative stress and liver damage. Additional studies include death receptor signaling pathways, involving Fas/FasL, that regulate reactive stress and innate immune. Directly responsible for laboratory management. Taught medical physiology course for three years, and received the 2011 Outstanding LSU Teachers Award. Assisted with recruitment seminars, selection of graduate student candidates, decisions in graduate student committees, and organization of research conferences.

Tacoma, Wa

Lead in vitro diagnostics processing of over three thousand specimens per night. Job duties include subject data analysis, quality control/calibrations, and reagent preparation/reconstitution. Toxicological analysis of human samples help determine nephrological function of subject, drug toxicity, and the presents of adulterants. Exceptional experience in troubleshooting as a leader and team.

Worldwide

Serve as a medical specialist who encountered emergency scenarios on the battlefield and hospitals. Exceptional medical training and experience was gained at Landstuhl Regional Medical Center by rotating in more than 8 different clinics/wards involving critical care, cardiovascular therapy, orthopedics, pediatrics, hematology, respiratory care, clinical laboratory, and pharmacy. Worked in an emergency room in Weed Army Community Hospital as a ER tech/ward. Has healthcare experience and training in emergency medicine, cardiovascular physiology, intravenous infusion, pharmaceutical administration, vaccination, eye exams, patient administration/care/transport, drug testing, medical and diagnostic devices.

Doctor Of Philosophy (Ph.D.), Molecular And Cellular Physiology, 4.00

Activities and Societies: •2012 Oral Presentation Honors for LSU-Health Graduate Research Day •2011 Outstanding Teachers Award.

Bachelor'S Of Science, Cellular Biology Emphasis

Activities and Societies: Rock climbing, swimming, and weight lifting.Studied Cellular Emphasis Biology

Associate Of Science (A.S.), General Science

Studied General Sciences with a strong emphasis on Chemistry.

Associate Of Arts (A.A.), Allied Health, 3.87

Activities and Societies: •2001 Summa Cum Laudi, Dean’s Honors, Barstow CollegeAs a student, the primary goal was allied health activities.

Certificate, Primary Leadership Development Course

Activities and Societies: •2000 Army Ironman Competition Award •2000 Commandant’s Honor, U.S. Army Noncommisioned Officer AcademyAs.

Certificate, Medical Specialist

Activities and Societies: •Soldier of the MonthOur class primarily focused on hands-on medical training and emergency medicine classes.