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Isabella Tsai is a R&D Lead | Drug Development at Intelligene 智新生技. She possess expertise in molecular biology, research, protein chemistry, biochemistry, protein expression and 15 more skills. She is proficient in English.
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Principal ScientistIntelligene 智新生技 Sep 2024 - PresentTaipei City, Taiwan -
Manager, R&D Biomedical LaboratoryAcer Apr 2021 - Jul 2023⧫ Drug delivery technology platform development for AI-powered personalised cancer immunotherapy⧫ Led a multidisciplinary team: Molecular Biology | Chemistry | Medical Engineering⧫ Management of R&D projects and budget⧫ Investment evaluation to support corporate decision-makingHighlights of Transferable Skills○ Analytical & organisational skills: background research, evidence-based data interpretation and presentation, new target assessment, teamwork, time management○ Supervision & team building: leading a boutique team of PhD professionals with diverse expertise○ IT literate: Microsoft Office Suite, Adobe Suite, EndNote, PyMOL, CCP4 Suite, AlphaFold Colab, a range of bioinformatics online tools -
Senior Scientist In DiscoveryNovalgen Sep 2019 - Aug 2020London, United KingdomImmunotherapy company focused on novel bi-specific antibody development for haematological malignancies and solid tumours⧫ New target assessment: primary & secondary research, scientific data analysis, roundtable discussion ⧫ Assay development: information extraction, POC experiment design and execution, data interpretation ⧫ Antibody engineering: antibody format design, robust cloning techniques, validation⧫ Supported data documenting for stakeholders -
Postdoctoral ScientistThe Francis Crick Institute Aug 2014 - Aug 2019London, United KingdomCrick-GSK Biomedical LinkLabs ⧫ Executed multiple cross-organisational projects for 4 years between academia (Crick Institute) and pharmaceutical (GSK), worked alongside GSK scientists, presented in milestone meetings, internal and external seminars to focused and broader target audience ⧫ Established co-crystals of domain antibody-antigen as a fragment screening platform (first for E3 ligase) ⧫ Innovative approach to study structures and functions of ubiquitin ligases ⧫ Cultivated professional relationships with external biopharma scientists and internal technology platformHighlights of Scientific Expertise○ X-ray crystallography, compound soaking ○ Domain antibody discovery, phage display, high throughput expression system○ Protein-protein & protein-ligand interactions: ITC, SPR, BLI, co-IP○ Protein purification and characterisation: Affinity/IEX/HIC/SEC, ÄKTA equipment & UNICORN, PAGE, Western Blot○ Protein expression: bacterial and mammalian cell systems -
Visiting ScientistGlaxosmithkline Pharma Gmbh Aug 2015 - Mar 2016Stevenage, United KingdomCrick-GSK Biomedical LinkLabs⧫ Domain antibody discovery and dAb-Ag evaluation ⧫ Effective communication with multidisciplinary experts and integrated in pharma working mindset ⧫ Invited to publish personal and professional experience of the inaugural Crick-GSK collaboration -
Postdoctoral Research AssociateUniversity College London Feb 2012 - Jul 2014London, United KingdomNeuropilin 2 | Regulatory Zinc | VEGFA | Cardiovascular Development & Tumoregenesis⧫ Funded by British Heart Foundation (2y2m)⧫ First to discover unique regulatory zinc binding that detriments Neuropilin 2 and the rescue effect of heparin ⧫ First to describe the ligand (VEGFA) binding to Neuropilin 2 at atomic resolution Telomerase inhibition by a quadruplex ligand as an anti-tumour strategy ⧫ Funded by Pancreatic Cancer Research Fund (3m)⧫ Cancer and somatic cell culture⧫ Cytotoxicity assay, Senescence cell staining assay⧫ Supervised Erasmus student (MSc)
Isabella Tsai Skills
Isabella Tsai Education Details
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Biochemistry -
Biochemistry And Molecular Biology -
Biochemical Science And Technology
Frequently Asked Questions about Isabella Tsai
What company does Isabella Tsai work for?
Isabella Tsai works for Intelligene 智新生技
What is Isabella Tsai's role at the current company?
Isabella Tsai's current role is R&D Lead | Drug Development.
What is Isabella Tsai's email address?
Isabella Tsai's email address is gw****@****ail.com
What schools did Isabella Tsai attend?
Isabella Tsai attended University Of Cambridge, National Taiwan University, National Taiwan University.
What are some of Isabella Tsai's interests?
Isabella Tsai has interest in Dancing, Playing Piano.
What skills is Isabella Tsai known for?
Isabella Tsai has skills like Molecular Biology, Research, Protein Chemistry, Biochemistry, Protein Expression, Genetics, Cell Culture, Structural Biology, Western Blotting, Biophysics, Cell Biology, Affinity Chromatography.
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Isabella Tsai
Taipei -
Isabella Tsai
Taiwan1gmail.com -
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