Isabel Sousa, Ph.D. Email & Phone Number

Berlin, De

Berlin, Germany

Berlin Metropolitan Area

Berlin Area, Germany

- Early-stage startup focused on developing evidence-based microbiome-targeting nutritional supplements for various health conditions.- Responsible for product development and production: formulation development from literature research; sourcing of ingredients and suppliers; in-house testing and manufacturing.- Set up and monitored a small clinical study with beta testers: developed the study protocol in collaboration with the Forslund Lab at the Experimental and Clinical Research… Show more - Early-stage startup focused on developing evidence-based microbiome-targeting nutritional supplements for various health conditions.- Responsible for product development and production: formulation development from literature research; sourcing of ingredients and suppliers; in-house testing and manufacturing.- Set up and monitored a small clinical study with beta testers: developed the study protocol in collaboration with the Forslund Lab at the Experimental and Clinical Research Center of the Max Delbrück Center and Charité Berlin; monitored compliance, data collection and analysis; responsible for customer support.- Compiled and fact-checked scientific information for marketing communication. Show less

Remote

Copyediting of medical and life sciences manuscripts from ESL authors.

Berlin Area, Germany

Freising, Germany

• Experimentally validated computational predictions of non-coding variants underlying shared genetics between Type 2 Diabetes and Alzheimer's disease.• Managed 6 projects simultaneously, involving design and troubleshooting of molecular and cellular based assays, large data interpretation and application of new concepts to move projects forward.• Developed and executed experiments involving establishing cell culture as well as molecular and cell biology assays resulting in the… Show more • Experimentally validated computational predictions of non-coding variants underlying shared genetics between Type 2 Diabetes and Alzheimer's disease.• Managed 6 projects simultaneously, involving design and troubleshooting of molecular and cellular based assays, large data interpretation and application of new concepts to move projects forward.• Developed and executed experiments involving establishing cell culture as well as molecular and cell biology assays resulting in the elucidation of the mechanistic biology of candidate causal variants resulting in 1 high impact publication in the New England Journal of Medicine.• Independently developed and established new primary cell culture models and SOPs to be used by other lab members.• Successfully supervised 2 bachelor students with independent projects. Show less

Greater Boston Area

• Developed a new CRISPR/Cas9 gene editing method that allows scalable and accurate single nucleotide variant editing.• Troubleshot problems related to plasmid design, vector cloning and bacterial transformation resulting in improved method efficiency.

Heidelberg, Germany

• Characterized novel regulator genes controlling mesenchymal stem cell function and adipose tissue remodelling using RNAi loss-of-function experiments.• Designed and executed experiments including cell culture, molecular and cell biology assays resulting in the elucidation of the mechanistic biology of the top candidate genes resulting in 1 publication.• Established new protocols for FACS analysis of cell proliferation and survival to be used by other group researchers.

Coimbra, Portugal

• Evaluated the crosstalk between endoplasmic reticulum and mitochondria in diabetes-related neurodegeneration using primary neuronal cell culture and molecular biology assays.

Doctor Of Philosophy - Phd, Molecular Biology

Master'S Degree, Cellular And Molecular Biology, 19/20

Bachelor'S Degree, Biochemistry, 18/20