Isaiah Hoffman Email & Phone Number

Los Angeles Metropolitan Area

• Chartered H.O.M.I.E.S Inc as a 501c(3) nonprofit organization to mentor youth of African descent• Initiated documentation filing and notarization for notice of tax-exempt nonprofit incorporation, acquisition of an employer identification number, and submission to trademark H.O.M.I.E.S Inc’s name and image• Submitting documentation for westward expansion to charter H.O.M.I.E.S Inc. chapters in multiple states• Writing grants and pursuing corporate sponsorship in an attempt to hire… Show more • Chartered H.O.M.I.E.S Inc as a 501c(3) nonprofit organization to mentor youth of African descent• Initiated documentation filing and notarization for notice of tax-exempt nonprofit incorporation, acquisition of an employer identification number, and submission to trademark H.O.M.I.E.S Inc’s name and image• Submitting documentation for westward expansion to charter H.O.M.I.E.S Inc. chapters in multiple states• Writing grants and pursuing corporate sponsorship in an attempt to hire and manage full-time staff• Partner with North and West Philadelphia middle & high schools to provide Black youth with tools and guidance to prepare for career paths involving higher education, career trade training, and STEM fields• Prioritize impromptu tutoring sessions for mentees who need immediate academic assistance • Provide personal testimonies through shared experiences to create safe spaces for Black youth• Organize fundraising events to support members with SAT, ACT, and/or college application expenses• Create and analyze online surveys for ideal mentor-mentee pairings• Keep detailed records of information such as signed waivers, mentor/mentee rosters, and purchase receipts Show less

Santa Monica, California, United States

• Conduct ddPCR-based method development activities within Quality Control sites to test for concentrations of the residual host cell and plasmid impurities in project samples • Employ quality by design (QbD), design of experiment (DOE), and statistical approaches to method development to identify robust operating range within phase-appropriate pre-defined acceptance criteria aimed to meet International Council for Harmonisation (ICH) guidelines• Execute, analyze, and use good… Show more • Conduct ddPCR-based method development activities within Quality Control sites to test for concentrations of the residual host cell and plasmid impurities in project samples • Employ quality by design (QbD), design of experiment (DOE), and statistical approaches to method development to identify robust operating range within phase-appropriate pre-defined acceptance criteria aimed to meet International Council for Harmonisation (ICH) guidelines• Execute, analyze, and use good documentation practices to document experiments that support routine development activities, innovation, investigations, and project goals• Work cross-functionally with clinical and commercial QC during knowledge, method and tech transfer, and co-qualification/validation• Author and review accurate technical, development and qualification reports to support regulatory filings Show less

Philadelphia, Pennsylvania, United States

• Extracted human, feline, deer, and mouse intestinal crypts to culture into 3D organoids• Cultured organoids utilizing protocols such as passaging, cryofreezing, cryorecovery, and 2D conversions• Infected 2D monolayers with an agonist such as poly (I:C) in preparation for BSL3 Sars-CoV-2 infection• Performed RNA extractions, cDNA conversions, and polymerase chain reactions for organoid agonist trials• Stained and imaged 2D organoid monolayers using appropriate antibodies and… Show more • Extracted human, feline, deer, and mouse intestinal crypts to culture into 3D organoids• Cultured organoids utilizing protocols such as passaging, cryofreezing, cryorecovery, and 2D conversions• Infected 2D monolayers with an agonist such as poly (I:C) in preparation for BSL3 Sars-CoV-2 infection• Performed RNA extractions, cDNA conversions, and polymerase chain reactions for organoid agonist trials• Stained and imaged 2D organoid monolayers using appropriate antibodies and widefield microscopy • Managed various strains of mice in a colony by breeding, weening, euthanizing, and genotyping Show less

Philadelphia, Pennsylvania, United States

• Provided graduate-level tutoring within Drexel’s College of Biomedical Sciences and College of Medicine• Served as an academic coach teaching studying strategies and methods for success in STEM related courses• Created structure and applicable strategies for academic success based on individual student needs• Broke down scientific material and present it in a manner which is easily digestible to each student• Presented study tools that aid in time management, self-care, and… Show more • Provided graduate-level tutoring within Drexel’s College of Biomedical Sciences and College of Medicine• Served as an academic coach teaching studying strategies and methods for success in STEM related courses• Created structure and applicable strategies for academic success based on individual student needs• Broke down scientific material and present it in a manner which is easily digestible to each student• Presented study tools that aid in time management, self-care, and approaching course content Show less

Philadelphia, Pennsylvania, United States

• Utilized marketing methods to increase awareness of Princeton Review events and free products• Planed, organized, and financed events for MCAT, LSAT, GMAT, GRE, and DAT preparation• Coordinated events with student group leaders on campus to spread awareness of free test prep materials• Proctored free practice test events in Philadelphia and surrounding areas

Philadelphia, Pennsylvania, United States

• Tutor students in the subjects of biology, biochemistry, chemistry, psychology, and sociology• Provide additional support for homework help, test prep, and/or general studying tips• Present STEM material in a manner that is easily digestable to high school and college students

Philadelphia, Pennsylvania, United States

• Lead, design and maintain R-programming & analytical data for research projects• Created various surveys via Qualtrics, and analyze the network data for publication• Managed data collection by creating excel spreadsheets and lab data memos• Served as liaison between Autism Institute and partnering collaborators at Thomas Jefferson University• Produced and edited research publication drafts as well as community reports for suicide prevention

Philadelphia, Pa

•Conduct research under Tara Davis, Ph.D•Prepare DNA pellets using tissue culture splitting and transfection methods• Study the role that the eight major nuclear cyclophilins play in spliceosome assembly and regulation of splicing chemistry but focused on a single cyclophilin and its potential interaction network• Remove introns from pre-MRNA via splicing to release intron sequence from the pre-mRNA… Show more •Conduct research under Tara Davis, Ph.D•Prepare DNA pellets using tissue culture splitting and transfection methods• Study the role that the eight major nuclear cyclophilins play in spliceosome assembly and regulation of splicing chemistry but focused on a single cyclophilin and its potential interaction network• Remove introns from pre-MRNA via splicing to release intron sequence from the pre-mRNA substrate and join together flanking exons• Verified interactions for individual cyclophilins, both by utilizing directed yeast two-hybrid assays and by co-immunoprecipitation (Co-IP) of cyclophilins out of human nuclear extracts• Used ligation-independent cloning (LIC) techniques to clone and screen for soluble expression constructs for cyclophilin-interacting splicing factors, with the eventual goal of structural determination via x-ray crystallography Show less

• Conduct Research under David Kutzik, Ph.D• Creating community based networks of volunteers and/or advocacy organizations within the local aging network• Analyzing the state of health and wellness promotions for frail elderly living within a community Screened for relevant information using the computerized patient record system and patient intake forms• Working to evolve into a project that moving forward has a specific opportunity and need for mixed method participatory action… Show more • Conduct Research under David Kutzik, Ph.D• Creating community based networks of volunteers and/or advocacy organizations within the local aging network• Analyzing the state of health and wellness promotions for frail elderly living within a community Screened for relevant information using the computerized patient record system and patient intake forms• Working to evolve into a project that moving forward has a specific opportunity and need for mixed method participatory action research Show less

• Attendee of Dr. Charles Nelson• Shadowed Dr. Nelson as he evaluated pre- and post-operation outpatients • Witnessed joint replacement surgeries• Spoke with post-surgery inpatients to track their progress following procedures

Greater Philadelphia Area

• Drexel University Cooperative Education Program• Assisting researchers in physical therapy and rehabilitation sciences, creative arts therapies (Art, Music, and Dance/Movement), nutrition sciences, and individual, couple and family therapy• Confirming insurance coverage’s for each patient, to determined the correct co-payment and deductible amount for each patient• Organize and process weekly check and credit card statements • Electronically document proof of payment… Show more • Drexel University Cooperative Education Program• Assisting researchers in physical therapy and rehabilitation sciences, creative arts therapies (Art, Music, and Dance/Movement), nutrition sciences, and individual, couple and family therapy• Confirming insurance coverage’s for each patient, to determined the correct co-payment and deductible amount for each patient• Organize and process weekly check and credit card statements • Electronically document proof of payment, insurance information, and updated patient charts• Health Insurance Portability and Accountability Act (HIPAA) Certified (Valid through April 2018) Show less

Greater Los Angeles Area

• Attendee of Dr. Charles Liu and Dr. Jonathan Russin • Witnessed surgeons perform Neurosurgical operations on patients• Attended Department of Neuroscience’s weekly meetings where physicians and scientists discussed procedure methods for the upcoming week, debated sbout which approach to take for a specific type of trauma post-operation healing strategies, and success rates after patients one year post surgery evaluations• Educated on the use of cranial surgical equipment for… Show more • Attendee of Dr. Charles Liu and Dr. Jonathan Russin • Witnessed surgeons perform Neurosurgical operations on patients• Attended Department of Neuroscience’s weekly meetings where physicians and scientists discussed procedure methods for the upcoming week, debated sbout which approach to take for a specific type of trauma post-operation healing strategies, and success rates after patients one year post surgery evaluations• Educated on the use of cranial surgical equipment for aneurism and tumor removal as well as the importance of early treatment of cranial cancers Show less

Doctor Of Medicine - Md

Interdisciplinary Health Sciences, Medical Post-Baccalaureate, 3.8

Successfully pursued an opportunity to enhance my academic credentials and demonstrate an ability to succeed in science courses.

Continuing Education, Biomedical Sciences, General

Developing knowledge on research techniques and applications of biology in medical practices which may serve useful in a medical school.

Bachelor’S Degree, Sociology

Activities and Societies: National Association For the Advancement of Colored People, Alpha Phi Alpha Fraternity Inc, Minority Association.