Research Assistant
Vaccine Research Group, Department of General Internal Medicine •Assessed host immune responses to infections and vaccines (e.g., measles-mumps-rubella, influenza, SARS-CoV-2) using the following immunologic techniques: enzyme-linked immunosorbent assays (ELISAs), nucleic acid purifications, peripheral blood mononuclear cell (PBMC) isolations, PBMC-viral stimulations, hamster/mouse spleen/lymph node harvesting, surrogate virus neutralization tests, and ELISpot assays.•Developed an ELISA-based avidity assay to examine the strength of interaction of SARS-CoV-2-specific antibodies to nucleocapsid and spike proteins, respectively, in a longitudinal cohort of convalescent subjects. •Modified a SARS-CoV-2 surrogate neutralization test to quantify and investigate the cross-reactivity/functionality of antibodies to the receptor-binding domain of the vaccine strain and variants of concern (Alpha, Beta, Gamma, Delta, Omicron) in previously vaccinated subjects. •Achieved proficiency in computing statistical analyses and creating figures using the R programming language (ggplot2 package).